Search PubMed⌕ Search

Biomedical subjects

E Steinbach

Publications and source records attributed to E Steinbach.

At least 37 records · Page 2Linked to original sources
PubMed1983

The effects of fibrin tissue adhesive on the middle ear.

This study investigated the effects of fibrin glue ('Tissucol', Immuno Pty. Ltd.) in the middle and inner ear. Small amounts of the adhesive were used in 36 operations performed on 18 rabbits. The light microscopic examination of these ears four, eight and 12 weeks after surgery showed that the adhesive was well tolerated and that it did not have any toxic effect on the middle ear or membranous labyrinth. The fibrin tissue adhesive can therefore safely be used to facilitate reconstructive middle-ear surgery and, with the aid of fascia, also for the closure of labyrinthine fistulae; or to achieve a definite seal of oval window niche after stapes surgery.

Animals↗
PubMed1982

[The value of labyrinthectomy in the treatment of Menière's disease (author's transl)].

Surgical labyrinthectomy in patients with Menière's disease produces unsatisfactory results in 10-70% of the cases. A pathological process in the vestibular nerve comprising an increase in connective tissue formation and the development of bony material within the nerve is possibly the reason for the pathological function of the vestibular system. This process may arise after a mechanical trauma to the labyrinth. Labyrinthectomy should be performed only for the treatment of Menière's disease if other therapeutical regimens or neurectomy under general anaesthesia cannot be tolerated by the patients.

Cochlear Nerve↗
PubMed1982

[A clinical and experimental study on precious metal ventilation tubes (author's transl)].

Incompatibility reactions which lead to a profuse aural discharge and often necessitate the removal of the ventilation tube occur in approximately 10% of patients if ventilation tubes made of synthetic materials are used. We have used golden and other precious metal alloy grommets in patients after extensive bacteriological and animal experiments. The most important advantage is the oligodynamic action which gives the surface of the ventilation tube repellent properties against bacteria. The drainage function is excellent due to the smooth surface structure and no incompatibility reactions were seen.

Drainage↗
PubMed1982

[Pathogenesis of chronic recurrent parotitis (author's transl)].

A combination of several factors is of importance in the pathogenesis of sialectatic parotitis. Stenson's duct is relatively long and its orifice is narrow. The flow of the saliva may be impaired, especially when mastication is abnormal or when the ductal lumen is scarred because of infection or trauma. Dental or oral mucosal disease may increase the number of pathogenic organisms which might then lead to a retrograde ascending infection. This is followed by epithelial desquamation and subsequent ductal obstruction. Allergic, genetic an racial factors in sialectatic parotitis are also discussed. The four characteristic progressive histologic stages of sialectatic parotitis are: a periductal inflammatory reaction, a diffuse lymphocytic sialadenitis with dilated ducts, fully developed sialectatic parotitis and, finally, fibrosis of the parotid gland. Conservative treatment will lead to an improvement of the clinical symptoms as well as the histopathological features in the first two stages, but in the two final stages total parotidectomy, with preservation of the facial nerve, is the treatment of choice.

Adolescent↗
PubMed1982

[A light and electron microscopic study of the squamous epithelium of the external canal and drum in experimentally induced cholesteatoma in guinea pigs].

The skin of the postero-superior part of the meatus and drum of guinea pigs was treated with enbucrylate and examined via light microscope and electron microscope after three weeks. The squamous epithelium was thickened with extensive rete pegs in the subepithelial space. The epithelial cells were loosely arranged and their nuclei pathologically changed. In the oedematous perimatrix small finger-like epithelial proliferations and activated mesenchymal cells could be seen.

Animals↗
PubMed1980

The effects of an adhesive in the middle ear.

This study investigated the effects of enbucrilate (Histoacryl) on the middle ear. Small amounts of the adhesive were used in 81 middle-ear operations performed on 50 rabbits. Light microscopic investigation of these ears 1, 2, and 3 months after surgery showed bone necrosis and a granulation tissue reaction surrounded by foreign-body giant cells. Inner-ear changes were observed in a third of the cases. Therefore, enbucrilate should only be used with extreme care and in minute quantities and never near the labyrinthine capsule.

Animals↗
PubMed1980

Experimental production of cholesteatoma in rabbits by using non-irritants (skin tolerants).

The application of various skin tolerant substances to the postero-superior and antero-inferior aspects of the external auditory canal of the rabbit, with an intact ear drum and middle ear, produced cholesteatomas in the skin of the auditory canal and in the tympanic membrane, particularly in the pars flaccida. At the antero-inferior insertion of the tympanic membrane, however, cholesteatoma growth could not be induced in these animal experiments. In severe diffuse otitis externa, secondary to the operative closure of the external auditory canal, cholesteatomas also develop preferentially in the pars flaccida. The relatively thick, loose intermediate layer of connective tissue allows a rapid expansion of epithelial ridges, thus favouring the formation of cholesteatoma in this region.

Animals↗
PubMed1980

Middle ear tuberculosis.

Fourteen cases of tuberculous otitis media are reported. With the declining incidence of pulmonary tuberculosis, the number of reported cases of tuberculous otitis media has become scanty. Nowadays the so-called classical signs of the lesion such as a profuse discharge, profound hearing loss, facial paralysis and multiple perforations, are hardly ever seen. Surgical intervention when done under cover of anti-tubercular drugs has no deleterious effect on the result of surgery. In order not to miss tuberculous otitis media, whenever the otologist is dealing with chronic middle ear disease, the following points should always be kept in mind: (a) A dull ache in the ear without obvious inflammatory signs. (b) A whitish-grey appearance of the mucosa. (c) Bulging of granulation tissue from the mastoid cells during surgery.

Adolescent↗
PubMed1978

[On the importance of cholesterol granuloma (author's transl)].

Cholesterol granuloma consists of solid metabolic waste products. The essential cause is a closed unaerated space in the middle ear cleft with proliferation of the mucosa, a connective tissue increased production of mucous and their subsequent organisation. During the resorption of this poorly digestable mucous cholesterol crystals are formed which in turn leads to small haemorrhages, increased fibrous tissue formation as well as the accumulation of foreign body giant cells. The analysis of 101 specimens showed different histological forms of cholesterol granuloma due to the different duration of the local pathological process. In the final stages the granulation tissue undergoes dystrophic calcification or necrosis. There is no influence on the adjacent bone. Cholesterol granuloma does not seem to be an important clinical entity. The therapy is the same as for the infectious process that is also present in the same ear.

Adult↗
PubMed1978

[Experimentally produced cholesteatoma (author's transl)].

Application of various mildly irritant substances to the posterosuperior and anteroinferior aspects of the external auditory canal of the rabbit, with intact ear drum and middle ear, produced cholesteatomas in the skin of the auditory canal, and the tympanic membrane particularly in the pars flaccida. At the anteroinferior insertion of the tympanic membrane, however, cholesteatoma growth could not be induced in these animal experiments. In severe diffuse otitis externa, secondary to the operative closure of the external auditory canal, cholesteatomas also preferably develop in the pars flaccida, the relatively thick, loose intermediate layer of connective tissue allows a rapid expansion of epithelial ridges thus favouring the formation of cholesteatoma in this region.

Animals↗
PubMed1977

Histologic fate of tympanic membrane and ossicle homografts.

1. The biologic behavior and usefulness of homologous incus grafts preserved in Cialit compare favorably with that of ossicular autografts. 2. Reconstruction of the transplanted incus correlates with the period of its immersion in preservative: the briefer the period of exposure to fixative, the more rapidly resorption and substitution occur. The longer the preservation time, the slower the rate of incus transplant reconstruction. 3. The preserved heterograft bone chip is unsuitable, since it disintegrates completely irrespective of the duration of its preservation. 4. The configuration of all bone chips is extensively altered after implantation. Autograft and homograft bone chips are both poorly tolerated. Chemical fixation does not alter this reaction. Fragments are shortened, softened, and rounded off. Heterologous bone chips are completely resorbed.

Animals↗
PubMed1975

[Uncommon findings during surgery of the internal auditory canal (author's transl)].

The following cases are demonstrated:postoperative deafness probably caused by abnormal blood supply to the cochlea, clinical findings of an acoustic neuroma without tumor, atrophy of cochlear and vestibular nerves, bone-like tissue growth in the labyrinthine trauma, hearing improvement after removal of an arachnoid cyst from the internal auditory canal.

Adolescent↗