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Biomedical subjects

E Steiger

Publications and source records attributed to E Steiger.

At least 55 records · Page 3Linked to original sources

The role of intravenous hyperalimentation in intestinal disease.

This article has dealt briefly with intravenous nutrition in intestinal disorders. The indications for its use and techniques of nutritional assessment have been stressed. The use of intravenous hyperalimentation in a few of the more common diseases of the small bowel and colon has been discussed. Every patient with disease of the small or large intestine has some degree of dysfunction in the gastrointestinal tract. In many instances, this functional impairment interferes with normal ingestion or absorption of nutrients and predisposes the patient to malnutrition. The presence of malnutrition increases the morbidity and mortality of surgery and can be reversed by using intravenous hyperalimentation. Those patients with extreme short bowel syndrome secondary to intestinal disease or its parenteral nutrition at home. We stress the importance of a team approach to hyperalimentation. The evolution of a team of nutritional experts will improve the care of the patient and the education of the patient and physician and make nutritional support more readily available to those medical and surgical patients in need.

Anthropometry↗

[Sterile packing materials for formaldehyde sterilization].

Apart from the already widely applied sterilization by ethylene oxide, the sterilization by gaseous formaldehyde is another reliable procedure for the sterilization of thermolabile instruments. An essential advantage of the sterilization by gaseous formaldehyde over the so-called wet sterilization is that it can be performed in a recontamination-proof sterile packing. Packing materials produced in the GDR, the germ-tightness and toxicological safety of which were already known, were tested to evaluate their suitability for sterilization by gaseous formaldehyde. An appropriate packing variant was found and tested for microbiological reliability.

Equipment and Supplies↗

Home parenteral nutrition.

Home parenteral nutrition is a life-sustaining mode of therapy for patients with short bowel syndrome that is unresponsive to conventional therapy. It requires learning specialized skills through an intensive training program and carefully following this program in a home setting. This training can be best provided by a group of health care specialists including a physician, nurse, dietitian, psychiatrist, social worker, and pharmacist who are knowledgeable about the issues that face the patient requiring home parenteral nutrition. The resources of career medical centers ar most appropriately utilized to provide the support needed to successfully undertake a home parenteral nutrition program. The nutritional requirements of these truly long-term patients have to be more accurately defined to guarantee that macronutrient and micronutrient requirements are being adequately provided for over the many years of required treatment. Fluid delivery systems and techniques for infection-free long-term venous catheterization have to be perfected. Home parenteral nutrition is a valuable life support system for patients with gut failure. Although expensive, it costs substantially less than in-hospital parenteral nutrition and can return the patient to a near normal life at home.

Home Care Services↗

Cost of a home parenteral nutrition program.

We analyzed the costs to a hospital of providing complete home parenteral nutrition (HPN) services for eight patients. Identified cost components include patient training, equipment, supplies, and follow-up. The average annual cost of maintaining parenteral nutrition at home was 73% lower than it would have been in the hospital. The establishment of private companies to provide patients with HPN supplies and services will reduce the financial burden of HPN programs for hospitals.

Costs and Cost Analysis↗

Home parenteral nutrition in management of patients with severe radiation enteritis.

Five patients who would have been unable to survive because of intestinal complications of radiation therapy were able to lead an otherwise normal life with the use of parenteral nutrition administered at home. One patient died of recurrent carcinoma of the cervix after 14 months. Another patient died as the result of a totally avoidable pharmaceutical error after 2 1/2 years. The remaining three are still disease free without morbidity relating to the parenteral nutrition.

Adult↗

Home parenteral nutrition for the short bowel syndrome. Psychological issues.

Home parenteral nutrition (HPN) for the short bowel syndrome represents a treatment modality that raises issues about prolonged machine dependency for living. Psychological reactions are described for patients with inflammatory bowel disorders and anatomical loss of small bowel. Liaison psychiatry involvement with 50 patients in the HPN program has identified such problems as grief reactions, depression, organic brain syndromes, drug dependency, and body image changes as they influence the initial adjustment to the in-hospital phase of HPN learning for patient and family. The importance of family and mental status examination are emphasized in the evaluation of the patient before and during the institution of an PHN program. Outlined are psychological parameters that need to be considered when assessing what factors might impede or enhance the acquisition and use of HPN information.

Adult↗

Nutritional support of the critically ill child.

New techniques for meeting the special metabolic requirements of the pediatric patient and the specific nutritional needs created by different disease states have become available both in enteral feeding and parenteral nutrition. Assessment of nutritional status and requirements of critically ill children are outlined, and the indications, techniques of administration, and complications of the available nutritional modalities are discussed.

Adolescent↗

Hypouricemia in total parenteral nutrition.

Profound hypouricemia developed in significant number of patients receiving total parenteral nutrition. Nadir serum uric acid (values between 1 and 2.7 mg/100 ml) were noted between the 2nd and 17th day of the course. Return of serum uric acid to pretreatment values was noted within seven days after the termination of total parenteral nutrition. In an effort to explain this phenomenon urine uric acid and uric acid clearance were measured in a subsequent group of patients before and during the course of total parenteral nutrition was not directly identified.

Creatinine↗

Maintenance of home hyperalimentation in patients with high-output jejunostomies.

We studied four patients with high-output end jejunostomies (greater than 3,000 mL/day) who were receiving home hyperalimentation. With knowledge of urine and stoma output, standard total parenteral nutrition fluid was infused and titrated according to individual needs, first during the hospital stay and then on follow-up office visits. Mean daily stoma output for the group was 3,556 mL/day. With oral fluid intake restricted to 1,500 mL/day, average daily stoma output dropped to 2,892 mL. The mean daily volume of nutrient fluid required to achieve stabel biochemistries and weight was 3,550 mL. Daily caloric requirements ranged from 23 kcal/kg to 44 kcal/kg, with a mean of 32.5 kcal/kg. Amino acid requirements averaged 1.6 g/kg. With 65 patient months of continuous overnight catheter infusion, there have been no serious metabolic derangements or deaths. The program of home hyperalimentation can maintain a satisfactory metabolic state in patients with high-output jejunostomies.

Amino Acids↗

Effect of protein depletion and repletion on liver structures, nitrogen content and serum proteins.

The data presented in this paper demonstrate that a liver which has been severely damaged by protein malnutrition can be restored to normal composition, anatomy and functional capability by central venous feeding. An atypical serum protein electrophoretic pattern characterizes protein malnutrition. TPN repletion restores all of the protein fractions back to normal except for the gamma globulin levels. Liver nitrogen is a very sensitive index of both protein malnutrition and TPN repletion. The liver is dramatically effected by protein malnutrition and its return toward normal can be achieved by TPN support as demonstrated in this paper.

Animals↗

The current status of home total parenteral nutrition.

The history and current status of home total parenteral nutrition are reviewed. Patients without a functional intestinal tract are able to lead a relatively normal life, infusing their essential nutrients through a Silastic central venous catheter while they sleep at night. The average catheter life is nine months. Suspected sepsis and obstruction of the catheter were the leading causes for catheter removal.

Artificial Organs↗