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Biomedical subjects

E Snir

Publications and source records attributed to E Snir.

27 records · Page 2Linked to original sources

Current surgical technique to repair Fallot's tetralogy with absent pulmonary valve syndrome.

The experience with surgical repair of Fallot's tetralogy and absent pulmonary valve syndrome is reviewed. Twenty-two patients aged 1 day to 8 years were treated between 1982 and 1989 using one surgical technique. This consisted of resection of the main pulmonary artery and large parts of the anterior wall of the right and left pulmonary artery. The ventricular septal defect was closed with a patch, and an aortic or pulmonary homograft (size, 8 to 24 mm) was interposed between the right ventricle and the pulmonary artery. Two of the 8 infants operated on died; there was one late death. All 14 older children survived the operation. All survivors are well up to 7 years follow-up (mean follow-up, 3.6 years). We recommend early treatment of infants; older children can be treated electively. The technique used in our series gives excellent results.

Child↗

Management of major tracheal hemorrhage after repair of complex congenital heart defects.

Two patients with complex congenital heart defects (a 4-year-old with transposition of the great arteries, ventricular septal defect, and left ventricular outflow tract obstruction and a 3 1/2-year-old with double-outlet right ventricle, subpulmonary stenosis, and complete atrio-ventricular septal defect) suffered multiple major hemorrhages from the tracheobronchial tree (28 and 7 bleeding events, respectively). Successful management included tracheostomy, sedation and paralysis, systemic hypotension, and systemic hypothermia for a period of seven days. Both patients survived.

Anesthesia↗

Effective technique of sternum closure in high-risk patients.

A successful technique of closing the sternum in a selected group of poor-risk patients involves the combination of a mattress suture and a fixative single-wire suture, both of 0 stainless-steel monofilament. Our technique was used on 100 high-risk patients and compared with double control groups, one consisting of 200 normal-risk patients and the second of 100 high-risk patients. We found that the incidence of wound infections was reduced to 1% with our new technique compared with 3% and 1% in the control groups (the high- and normal-risk groups, respectively). There was neither dehiscence nor mediastinitis in the study group, compared with 1% and 0.5% incidences of these complications in the controls. Also, there was no mortality in the combined-closure group compared with mortality of 0.5% and 1% in the control groups. We believe that this closure effectively strengthens the complex of bone and wire, improving the stability of the chest by giving a correct axis to the sternum. It is also cost-effective and easy to perform and does not prolong operation time.

Aged↗

Dissecting aortic aneurysm in pregnant women without Marfan disease.

Dissection of the young women without Marfan disease is related, in most instances, to pregnancy. The structural changes in the arterial wall that occur during pregnancy may predispose women to this complication of pregnancy. In this study, two young women, who had none of the characteristics of Marfan's syndrome, were operated upon for dissection of the ascending aorta. The first patient was in the 35th week of gestation and a cesarean section was performed prior to replacement of the ascending aorta. In the second patient, diagnosis of dissection and severe aortic regurgitation occurred in the postpartum period. Knowledge of this albeit relatively rare complication of pregnancy may assist the clinician in diagnosing and referring patients early for surgical treatment that, in most instances, may save the lives of both mother and fetus.

Acute Disease↗

Rupture of chordae tendineae associated myxoma of the left atrium.

Mitral insufficiency is unusual in patients with left atrial myxoma. A patient with myxoma of the left atrium presented with acute pulmonary edema due to ruptured chordae tendineae. Both lesions were unequivocally demonstrated by echocardiography, permitting emergency surgical correction to be undertaken without recourse to angiographic studies. Despite the rarity of acute mitral regurgitation due to rupture of chordae tendineae in association with left atrial myxoma, with only one such case previously reported, an etiologic relationship between the two disorders can be postulated. The association between the two thus should not be unexpected.

Aged↗

Metabolic effects of intramuscular and oral administration of ritodrine in pregnancy.

The metabolic effects of ritodrine, 80 mg/day, administered intramuscularly in the third trimester of pregnancy to 14 patients for 5 days and per os to 10 patients for 10 days were investigated. Each patient was considered at high risk for premature labor. Intravenous glucose tolerance and insulin, triglyceride, and electrolyte levels were assessed before and at the end of treatment with ritodrine. Intramuscularly or orally administered ritodrine in 10-mg doses 8 times a day did not influence carbohydrate homeostasis. Triglyceride levels fell significantly after intramuscular administration, whereas serum potassium levels increased during treatment. This study suggests that ritodrine administered intramuscularly or orally is metabolically safe in nondiabetic pregnant women.

Administration, Oral↗