Search PubMed⌕ Search

Biomedical subjects

E Skog

Publications and source records attributed to E Skog.

45 records · Page 3Linked to original sources
PubMed1965

Sensitization to p-phenylenediamine.

p-Phenylenediamine (PPD) from 0.2 mg to 1.6 mg in water or in petrolatum was applied as a patch test to 501 patients with different dermatoses, asthma, hay fever, and venereal diseases. Of these patients 10.6% reacted within the first five days indicating previous hypersensitivity and 14.4% between the sixth and the 16th day indicating the initiation of hypersensitivity to PPD by the patch application (flare-up). The reactions within the first five days were not correlated with the amount of PPD in the tests, but a statistically significant correlation was found between flare-ups and amount, so that the larger the amount of PPD the higher the frequency of flare-ups. About one half of both reactions occurred in patients with eczematous dermatitis.

Adolescent↗
PubMed1965

Percutaneous absorption of trivalent and hexavalent chromium. A comparative investigation in the guinea pig by means of 51Cr.

By means of an in vivo isotope technique, the so-called disappearance measurements, a comparison was made during a five-hour period between the percutaneous absorption in the guinea pig of a trivalent (chromic chloride) and a hexavalent (sodium chromate) chromium compound. Nine different concentrations of each substance were studied. We found that in the concentration interval 0.017-0.239 molar the relative absorption of the hexavalent compound was somewhat higher, but the differences were not statistically significant. On the other hand, in the higher concentrations (0.261-0.398 molar) more of the hexavalent compound was absorbed, and the differences were statistically significant. This difference in percutaneous absorption for various concentrations can perhaps account for the divergent results, in respect to the absorption of trivalent and hexavalent chromium compounds, which have recently been published.

Animals↗