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Biomedical subjects

E Sivalingam

Publications and source records attributed to E Sivalingam.

7 recordsLinked to original sources

Alternative method for sulcus fixation of posterior chamber lenses in the absence of capsular support.

The realization that posterior chamber intraocular lenses have many advantages over anterior chamber ones has induced many practitioners to try methods of fixating the lenses in the ciliary sulcus when there is inadequate capsular support. Most of these methods require the use of sutures to anchor the lens to the sclera or the iris. We describe a modification of these techniques which allows the surgeon to place a stiff all-polymethylmethacrylate (PMMA) lens in the sulcus in a way that makes it unnecessary to anchor the lens, although a safety suture may be placed through the scleral lip. We believe this modification makes sulcus fixation simpler to perform and possibly safer for the patient. We have used this technique in six patients with good results.

Aged

The partial-punch: a new combined cataract-glaucoma operation.

This report describes a new combined cataract extraction-glaucoma procedure. The technique is a modification of a standard filtration type of operation. The essential step is the development of a shelved posterior scleral lip, 4 mm of which is excised; full thickness sclera is not removed. This permits tight incisional closure, but with the presence of a "valve" permitting exit of aqueous under a prepared conjunctival flap should intraocular pressure rise significantly in the postoperative period. In 15 cases there were no serious complications, no flat anterior chamber, good pressure control in 14 cases, and filtering blebs in nine.

Cataract

Glaucoma: an overview.

Glaucoma is one of the leading causes of blindness. It is a public health problem. No race is exempted from getting glaucoma. In the United States there are more than 2 million people afflicted with this disease. Every effort should be made to detect those people at risk early, and adequately manage them to prevent blindness. Therefore, it is important than an awareness of this disease should be created among health care professionals and the general public. This will lead to the early detection and proper management of this disease to prevent blindness. Glaucoma is a group of ocular conditions that will lead to blindness if it is not controlled. Although our knowledge about this group of diseases has advanced much in the past few decades--as compared with earlier times--we still are ignorant about the finer points and details regarding the disease. A lot of basic and clinical research is required to further and completely understand it. Much research is being done toward better management of glaucoma. Many multicenter clinical trials are being conducted. Collection of data regarding glaucoma is ongoing and will contribute to a better understanding of glaucoma--and thereby better management of patients who develop glaucoma.

Blindness

Spectrum of trabecular pigmentation in open-angle glaucoma: a clinicopathologic study.

In eight patients with chronic open-angle glaucoma and associated trabecular pigmentation, trabeculectomy and peripheral iridectomy specimens were studied by light and electron microscopy. Clinically, three patients displayed signs of classic pigmentary glaucoma (Group 1). In the other cases chronic open-angle glaucoma was associated with varying degrees of expression of the full pigmentary glaucoma syndrome (Group 2). Histopathologic examination of peripheral iridectomy and trabeculectomy specimens from Group 1 showed: (1) marked focal atrophy and hypopigmentation of iris pigmented epithelium with an apparent delay in melanogenesis. The dilator muscle was thickened except for occasional thinned areas. (2) The trabeculectomy specimens revealed excessive amounts of pigmented epithelial melanosomes and moderate accumulation of electron-dense basement membrane-like material in the juxtacanalicular meshwork. Similar specimens from Group 2 showed: (1) minimal hypopigmentation of the iris pigmented epithelium with normal melanogenesis. The iris stroma and dilator muscle were normal. (2) Trabeculectomy specimens displayed excessive electron-dense basement membrane-like material in the juxtacanalicular meshwork and minimal to moderate accumulation of melanosomes.

Adolescent