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Biomedical subjects

E Simón

Publications and source records attributed to E Simón.

47 records · Page 3Linked to original sources
PubMed1995

Effects of the beta-adrenergic agonist salbutamol and its withdrawal on protein metabolism of lambs.

Rasa Aragonesa lambs were used to evaluate the repartitioning effects of a beta-adrenergic agonist and its withdrawal on nutrient metabolism. One group of animals (T-I) was fed salbutamol at a dose of 2 mg x kg-1 diet x day-1 for 38 days, while in another group (T-II) the beta-adrenergic agonist was discontinued in the diet 5 days before slaughter on the 43rd day. The semitendinosus muscle protein content increased (p < 0.05), while fat and collagen content decreased (p < 0.05) in the T-I group. These differences were not apparent in the group from which salbutamol was withdrawn. Muscle protein degradation was diminished (p < 0.05) in both treated groups. The serum free fatty acid level was markedly enhanced (p < 0.05) in the T-I group. Total essential amino acid serum levels were reduced (p < 0.05) after the withdrawal period. Ketogenic and urea cycle amino acids were reduced (p < 0.05) in the salbutamol-fed T-I group and glycogenic amino acids were diminished (p < 0.05) in the T-II experimental group. The data show that salbutamol is able to increase muscle content at the expense of fat stores in productive animals. However, these repartitioning effects are circumvented by a 5-day period of withdrawal, in which concomitant metabolic changes in lipid and protein turnover and plasma amino acid profiles occur.

Adrenergic beta-Agonists↗
PubMedDate not supplied

[Reconstruction of the floor of the nasal cavity, hemipalate, bucal cheek and lower lip].

We describe the surgical technique used to reconstruct a defect created by resection of a tumor of the palate, malar mucosa, lower lip and adjacent gingival mucosa. We used a microvascular radial forearm flap. A strip across the flap is de-epithelialized and the flap is folded in half at that point. The sides are used for the oral and nasal linings, respectively. The thinness of this flap, its vascularization and the length of its pedicle make this design possible. Four months after the surgery the patient was free of disease and had achieved adequate phonation and swallowing.

Carcinoma, Squamous Cell↗