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Biomedical subjects

E Siegelman

Publications and source records attributed to E Siegelman.

6 recordsLinked to original sources
PubMed2004

Interspinous bursitis in an athlete.

We present a case of L2/3 interspinous bursitis treated with extraspinal injections. No previous investigations have used fluoroscopically guided spinal injections to confirm the clinical relevance of the MRI features of this type of bursae. Autopsy studies have revealed an increased incidence of interspinous lumbar bursal cavities with advancing age. Afflicted patients present with localised, midline lower lumbar pain exacerbated by extension. In young athletes these symptoms can mimic spondylolysis. MRI is useful in detecting soft-tissue injury of the posterior elements. Fluoroscopically guided diagnostic and therapeutic extraspinal injections can be used for confirmation and treatment of pain from such bursae.

Adolescent↗
PubMed2001

Unusual patterns of hepatic steatosis caused by the local effect of insulin revealed on chemical shift MR imaging.

OBJECTIVE: We reveal the chemical shift MR findings of unusual patterns of hepatic steatosis caused by the local effect of insulin. CONCLUSION: Unusual patterns of hepatic steatosis can be seen on MR imaging. Such patterns result from localized high concentrations of insulin. A rim of hepatic steatosis surrounding insulinoma metastases and a subcapsular distribution of hepatic steatosis in patients with diabetes treated with peritoneal dialysis are two such patterns that can be revealed on chemical shift imaging.

Adult↗
PubMedDate not supplied

Rapidly enhancing hepatic hemangiomas at MRI: distinction from malignancies with T2-weighted images.

The purpose of this study is to describe a subset of atypical hepatic hemangiomas that enhance rapidly and diffusely and to determine whether heavily T2-weighted images could distinguish between atypically enhancing liver hemangiomas and hypervascular malignancies. A retrospective search of MR records identified seven patients with liver hemangiomas that demonstrated diffuse early enhancement and 23 patients with biopsy-proven malignant liver lesions that were hypervascular on dynamic gadolinium-enhanced MR images. Quantitative analysis of signal intensity measurements was performed on the T2-weighted images, heavily T2-weighted (TE > 140), and dynamic gadolinium-enhanced images. Blinded reader comparison of the T2-weighted images and gadolinium-enhanced images was performed. Hypervascular hemangiomas enhanced to a greater degree than hypervascular malignant liver lesions on the early phase gadolinium-enhanced images. Perilesional parenchymal enhancement was demonstrated in five cases of rapidly enhancing hemangiomas. Signal intensity and contrast-to-noise ratios on the heavily T2-weighted images of the hemangiomas were significantly greater than that of the hypervascular malignant lesions (P < .05). Hemangiomas were differentiated from the hypervascular malignant liver lesions with high accuracy (97-100%) by three blinded readers based on the T2-weighted images. A subset of hemangiomas have atypical rapid diffuse enhancement on dynamic gadolinium-enhanced images. These atypical hemangiomas can be distinguished from hypervascular malignant liver lesions on T2-weighted MR images.

Adult↗