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Biomedical subjects

E Shanon

Publications and source records attributed to E Shanon.

At least 19 recordsLinked to original sources
PubMed1988

Multifocal extraosseous eosinophilic granuloma of the head and neck.

Multifocal eosinophilic granuloma (Hand-Schüller-Christian disease) confined to soft tissues in the head and neck region is described in a man, 32 years of age. The lesions were detected at varying time intervals within a period of 14 months. They were located in the gingivae, the submaxillary salivary glands, the thyroid gland, and in the dermal lining of the external auditory meatus. Clinical, histologic, ultrastructural, and immunohistochemical findings are presented and discussed. Some of these findings go along with the tenet that the typical proliferating histiocyte in eosinophilic granuloma is a pathologic Langerhans' cell, or a close kindred to it.

Adult↗
PubMed1987

Adenocarcinoma of the epiglottis. Report of a case and review of the literature.

The larynx is rarely the site of an adenocarcinoma. About 60 patients were described in the literature, and the epiglottis was primarily involved in only three. We studied a fourth case in a 77-year-old man. Adenocarcinoma of the larynx is a highly lethal neoplasm that tends to spread to both regional lymph nodes and distant sites. Despite radical surgical measures, the cure rate is low.

Adenocarcinoma↗
PubMed1985

Parotid gland hemorrhage as a complication of coumarin compound ingestion.

Bleeding in the salivary glands represents a very rare complication of oral anticoagulant therapy. Only one such case has been previously described in the submandibular glands. To the best of our knowledge, we document the first case of hemorrhage in the parotid gland following the ingestion of coumarin compounds.

Administration, Oral↗
PubMed1985

Maturation of auditory brainstem potentials in neonates and infants.

Auditory brainstem evoked potentials (ABP) were recorded in 59 healthy neonates and infants whose age ranged from 3 days to 18 months (6 age groups). Latencies of individual waves and the interpeak latencies (IPL) of I-III, III-V and I-V were analysed. A different maturational pattern was observed in the pontomedullary and the pontomesencephalic segments of the brainstem. Latencies of all waves except wave I were longer in male than in female babies. Establishment of normative data related to the technical variables employed by the individual team is a sine qua non prerequisite for adequate neurological evaluation of ABP.

Auditory Pathways↗
PubMed1985

Sudden hearing loss in the elderly.

In elderly subjects suffering from presbycusis a clinical picture of sudden hearing loss, tinnitus and vertigo may be precipitated by a superimposed serous otitis media. Such an abrupt and dramatic sensory deficiency may be erroneously ascribed to an acute cochlear lesion and given grave prognostication. This situation was observed in 12 patients during a period of 2 years. Appropriate diagnostic evaluation revealed the true nature of the disease and simple therapeutic measures promptly restored the auditory function to its previous level.

Aged↗
PubMed1985

Measurement of auditory brain stem potentials in Bell's palsy.

Auditory brain stem potentials (ABP) were recorded in 27 patients with Bell's palsy during the early phase of the disease and 1-3 months later. Pathological findings were observed in 6 patients, the dominant features being prolonged brain stem transmission time and diminished amplitude of the second wave. The extension of the pathological process in the so called idiopathic peripheral facial paralysis appears to vary. The observation of brain stem involvement in some patients with Bell's palsy may have important clinical implications.

Adult↗
PubMed1984

Invasive multiple supraglottic squamous cell papillary carcinoma in an adult. Report of a case.

Invasive papillary squamous cell carcinoma of the supraglottic larynx is described in an adult male. The clinicopathological appearance was that of a multiple growth which displayed various gradients of neoplastic changes: in situ, microinvasion, frank invasion of cartilage and cervical node metastases. No previous history of radiotherapy was elicited. The growth was excised by supraglottic laryngectomy and neck dissection. Typical metastatic papillary formations were observed in lymph nodes.

Carcinoma, Papillary↗
PubMed1983

Sleep apnea following bilateral excision of carotid body tumors.

A patient is described who developed apnea, hypertention, and tachycardia following the excision of bilateral carotid body tumors. Hypertension and tachycardia resulted, most probably, from bilateral ablation of the carotid sinus and/or the nerve of Hering. These phenomena have been described in the literature. The pathogenesis of the apneic attacks may be related to the ablation of the peripheral sensory organs (both carotid bodies), interference with the function of the respiratory automatic control system, and impaired control of ventilation during non-REM sleep. Temporary unilateral paralysis of the hypoglossal nerve with partial airway obstruction possibly represented a mechanical trigger. The apneic attacks subsided but bouts of hypertention and tachycardia persist.

Adult↗
PubMed1981

Auditory function of Friedreich's ataxia. Electrophysiologic study of a family.

Hearing function and auditory brainstem potentials were evaluated in nine members of three generations of a family affected with Friedreich's ataxia. The characteristic findings were high-frequency sensorineural hearing impairment of varying severity and diminished or absent N1, N2, and N3 responses. These electrophysiologic aberrations correlate topographically with previously reported pathological observations.

Action Potentials↗
PubMed1981

Pontomedullary vs pontomesencephalic transmission time. A diagnostic aid in multiple sclerosis.

Caudal vs rostral transmission time has been studied in patients with multiple sclerosis (MS). In the majority of the cases, prolongation in latency was more severe in the caudal segment, which suggests that this part of the brainstem is more commonly affected in MS. The difference between pontomedullary and pontomesencephalic transmission time yields a variable that may prove a valuable adjunct in the electrodiagnosis of MS.

Adolescent↗
PubMed1981

Auditory brain stem responses in thyroid dysfunction.

A characteristic pattern of ABR was observed in hyper-and hypofunction of the thyroid gland. The most conspicuous change took place in the BSCT. Its value correlated well with the level of serum T4. Dynamic changes of ABR pattern were recorded during the development of myxedema and on return to an euthyroid state. This preliminary study suggests that examinations of ABR may serve as a tool in the overall assessment of thyroid status.

Adolescent↗
PubMed1981

Auditory brain stem responses in cerebellopontine angle tumors.

The characteristic features of auditory brain stem responses (ABSR) are described in seven cases of cerebellopontine angle tumors: five acoustic neuromas, one congenital cholesteatoma, and one meningioma. An attempt is made to correlate the N1 response with the degree of auditory nerve involvement, to gain information about the presence of brain stem displacement, and to evaluate the cranial extension of the lesion by recording responses to contralateral stimuli. The empirical nature of deductions based on crossed stimulation is emphasized. In tumors originating from the VIIIth nerve, the ABSR pattern is characterized by a well-defined N1 complex, indistinct or absent additional responses, and prolonged brain stem conduction time (BSCT) on the affected side whenever its assessment is feasible. Recording from the affected side on stimulation of the contralateral side may show normal responses from stations central to the auditory nerve in cases of small-sized tumors. Medium or large tumors may be accompanied by abnormal N2 and/or N3 responses suggesting involvement of these stations.

Adolescent↗
PubMed1981

Assessment of functional integrity of brain stem auditory pathways by stimulus stress.

The effect of increasing the repetition rate of click stimuli on auditory brain stem responses has been studied in young subjects with normal hearing, in old people and in patients with multiple sclerosis. The most conspicuous effects have been observed in the amplitude of the responses, especially waves II and V, and in the value of the brain stem conduction time. Increased stimulation rates may serve as a method for the assessment of the functional status of the lower auditory pathways in diverse pathological conditions.

Acoustic Stimulation↗
PubMed1981

The significance of acoustic admittance procedures in the audiologic evaluation of multiply-handicapped children.

The specific contribution of admittance procedures in the diagnosis of hearing impairment was studied in a group of 53 handicapped children. The value of admittance procedures was assessed in relation to that of otoscopy and pure tone audiometry. Admittance procedures and otoscopy were successfully performed in all but one of the children and indicated conductive pathology in about 40% of the subjects, whereas pure tone audiometry was not feasible or inconclusive in 30.2% of the subjects. In 5.7% of the subjects admittance procedures proved the only diagnostic tool.

Acoustic Impedance Tests↗