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Biomedical subjects

E Sforza

Publications and source records attributed to E Sforza.

At least 91 records · Page 5Linked to original sources
PubMed1989

[Hypothalamic temperature and thermogenesis of brown fat during desynchronized sleep in rats].

The relationship between hypothalamic temperature and deep interscapular temperature measured just below the brown fat lobes has been studied during desynchronized sleep at two ambient temperatures (24 degrees C and 4 degrees C) before and after adaptation (9 days) to cold (4 degrees C). The results show that the increase in hypothalamic temperature during this stage of sleep occurs independently of a transfer of heat from interscapular brown fat.

Adipose Tissue, Brown↗
PubMed1988

Physiological hypnic myoclonus.

Physiological hypnic myoclonus (PHM) was quantified during wakefulness and sleep in 7 normal subjects. PHM was evident during relaxed wakefulness and increased during stage 1 and especially REM sleep. In some muscles, however, (e.g., soleus) it showed no increase during sleep. PHM resembled simple fasciculation potentials, or, when repeated or in clusters, the fragmentary myoclonus in NREM sleep. Both 'hypnic' and 'myoclonus' are terms inappropriate to the description of this physiological spontaneous motor activity.

Adult↗
PubMed1988

REM sleep behavioral disorders.

REM sleep behaviors were recently described as wild, dream-enacting behaviors during REM sleep with loss of usual atonia on submental muscles. We examined 6 patients (5 M, 1F) with characteristic episodes of behavioral manifestations during REM sleep. Polysomnographic data indicate a decrease in first REM latency, an absence of stage 4 NREM, altered phasic motor activity and behavioral episodes during REM sleep even with normal chin muscle atonia. Three patients had Shy-Drager syndrome, 1 olivopontocerebellar atrophy and 2 patients had no neurological disease. The crucial importance of a disinhibited locomotor system during sleep appears to be responsible for this REM parasomnia.

Adult↗
PubMed1985

Effect of a new sulfa-trimethoprim combination (trimethoprim-sulfamethopyrazine) in typhoid fever. A double-blind study on 72 adult patients.

A double-blind study on 72 adult patients affected by typhoid fever was done utilizing a new sulfa-trimethoprim combination (trimethoprim-sulfamethopyrazine) versus the well-known combination trimethoprim-sulfamethoxazole. The dosage used for the new drug was 2 capsules (250 mg trimethoprim + 200 mg sulfamethopyrazine per capsule) the 1st day and 1 capsule for the following 14 days or 2 capsules (trimethoprim 80 mg + sulfamethoxazole 400 mg per capsule) twice daily for 15 days. Both drugs proved to be very effective according to the parameters considered. No complications (intestinal bleeding, perforation, etc.) occurred in any of the patients, and untoward effects were not observed. It is therefore our opinion that treatment of typhoid fever with a sulfa-trimethoprim combination is both effective and safe.

Adolescent↗
PubMed1983

Nocturnal headache: systemic arterial pressure and heart rate during sleep.

In order to evaluate autonomic nervous system changes occurring before nocturnal headache attacks, we studied three subjects (one male, two females) suffering from chronic migraine. All three patients underwent a nocturnal polygraphic recording including continuous monitoring of systemic arterial pressure and heart rate. Two subjects showed increases and irregularities of arterial pressure before awakening with headache. These changes began during N-REM sleep and lasted during REM sleep preceding the awakening with headache. Heart rate did not change before the attacks. These findings do not support the hypothesis that autonomic instability during REM sleep represents the precipitating factor of the attacks.

Adult↗
PubMed1976

A bioptic study of gastrointestinal mucosa in cholera patients during an epidemic in southern Italy.

A histological biopsy study of gastric and jejunal mucosa of eight acute cholera patients during an epidemic in Southern Italy was carried out. The study demonstrated in all patients an intact epithelial lining of gastric and jejunal mucosa, a moderate degenerative process of enterocytes, presence of inflammatory lesions manifested by edema, vascular congestion, mononuclear cell infiltrate of lamina propria, and discharge of goblet-cells mucus. These changes reverted to normal in a few days. The authors emphasize that, contrary to cholera patients of Asiatic areas in whom an underlying chronic spruelike enteropathy is very common, the histological picture observed in Western patients may be considered more specific since Vibrio cholerae acts upon a normal intestinal mucosa.

Biopsy↗
PubMedDate not supplied

[Meningoencephalitis caused by Listeria monocytogenes in adults. Description of 2 cases].

Two patients are presented who had Listeria meningo-encephalitis. They were both adults and reduced in defences against infections. The diagnosis was made by isolation of Listeria monocytogenes from cerebrospinal fluid cultures. One of the patients recovered; other died although therapeutic measures were promptly started. The Authors suggest the need for a careful research about Listeria infections in our country.

Adult↗
PubMedDate not supplied

[Renal complications of Asiatic cholera].

Seventy cases of cholera were admitted to Hospital during 1973 cholera epidemic; 49 showed the symptoms of renal failure, 19 of whom with anuria. Acute renal failure is caused from hypertonic or isotonic dehydration, metabolic acidosis and potassium depletion. Clinically the pattern of a tubulo-interstitial nephritis can be found; a short oliguric or anuric phase followed by a poliuric phase lasting about 10 days. The glomerular function usually cames back to normal in 20 days time. As for the therapy, 16 of the above mentioned 19 anuric patients received a conservative treatment only; 3 patients with preexisting chronic nephropathy required peritoneal dialysis. Only one patient died and one patient with lupic nephropathy was put on chronic haemodialysis treatment. Concluding: 17 patients out of 19 completely recovered their renal function.

Acute Kidney Injury↗