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Biomedical subjects

E Senior

Publications and source records attributed to E Senior.

6 recordsLinked to original sources
PubMed1990

Landfill co-disposal of phenol-bearing wastewaters: organic load considerations.

A multi-stage model, operated with single elution, was used to investigate the effects of organic loadings on the attenuation of a model phenolic wastewater in domestic refuse. Although 100% dissimilation of influent phenol (2-5 mmol dm-3) was recorded at a dilution rate of 0.007 h-1, partial inhibition of both phenol degradation and species competing with methanogens for a common electron donor(s) was apparent at concentrations greater than or equal to 4 mmol dm-3. On extended perfusion with 8 mmol phenol dm-3, the progressive inhibition of phenol dissimilation was not obviated by nutrient supplementation. Simultaneous degradation of the catabolic intermediate, hexanoic acid, and elevated methane release rates suggested that the transformation of phenol to hexanoate was rate limiting.

Biotechnology↗
PubMed1990

Control/promotion of the refuse methanogenic fermentation.

Although practiced for more than 7 millennia, the landfill disposal of refuse has, as yet, with few exceptions, been merely regarded as a low-cost disposal option and its exploitation potential has been largely ignored. Today, however, a number of possibilities are under consideration including the production of energy, chemical feedstock, value-added chemicals, carbon dioxide and protein; the use of refuse as an anaerobic filter for the co-disposal of industrial wastewater and sludge; and the restoration of impoverished soils by fresh or composted refuse addition. Development of these technologies, however, necessitates a comprehensive understanding of the fundamental microbiology and biochemistry of refuse catabolism. Existing fundamental knowledge underpinning these technologies will be considered in a series of review articles. In the first, control/exploitation of the solid-state refuse methanogenic fermentation is examined with specific reference to the effects of first-tier variable manipulations.

Biotechnology↗
PubMed1976

Enzyme evolution in a microbial community growing on the herbicide Dalapon.

A seven-membered microbial community capable of utilising the herbicide Dalapon has been isolated by continuous-flow enrichment culture. The composition of this community has remained remarkably stable over thousands of hours in a Dalapon-limited chemostat. During this period, however, one member of the community, Pseudomonas putida, acquired the ability to grow on Dalapon through the evolution of an extant dehalogenase.

Biological Evolution↗