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E Semetkowska-Jurkiewicz

Publications and source records attributed to E Semetkowska-Jurkiewicz.

16 recordsLinked to original sources
PubMed1994

[P1 blood group, secretion status and susceptibility to asymptomatic bacteriuria in diabetes].

Blood-group antigens found on uroepithelial cells and in the secretions may affect bacterial adherence and thereby the predisposition to urinary tract infection. We determined P1, Lewis-blood-group phenotype and secretor status in patients with diabetes mellitus: 12 with asymptomatic bacteriuria and 7 without its presence. There was no difference between the two groups in the distribution of the P1 phenotype. There was also no statistical difference in the distribution of the Lewis phenotype and secretor status, although there appeared to be general trend of higher number of Le (a+b-) phenotype and non-secretors present in the asymptomatic bacteriuria group. Further studies are necessary to determine the role of blood groups and secretor status in the pathogenesis and susceptibility to urinary tract infection.

Adult↗
PubMed1990

[Hyperglycemic hyperosmolar nonketotic coma].

Ten patients with the syndrome of non-ketotic hyperosmolar coma are described. The mean age of the patients was 62.3 +/- 17.12 years. One patient was 16 years old. In 9 cases the patients had type II diabetes, one had type I diabetes. In 7 cases the coma was the first sign of diabetes. The factor predisposing in most cases was infection. In the treatment-acting insulin and hypotonic solutions were given. In 2 cases clinical signs of the DIS syndrome were observed manifesting themselves with local changes, including mental disturbances. Heparin was given with good effect. Three patients (30%) died in hospital. The cause of death was serious disease associated with this coma: pancreatitis and myocarditis, purulent bronchopneumonia, myocardial infarction.

Adolescent↗
PubMed1980

Systolic and diastolic time intervals in young diabetics.

Systolic and diastolic time intervals were used to examine left ventricular performance in 22 young diabetic men (mean age 25 years) with no apparent clinical heart disease. Pre-ejection period index (PEPI), left ventricular ejection time index (LVETI), electromechanical systole index (QS2I), PEP to LVET ratio, the a wave percentage amplitude of the apexcardiogram (a/H5 ratio), the rapid filling wave (RFW), and the A2O interval were obtained in the conventional manner in 22 diabetics and 22 healthy men. The heart rate, diastolic pressure, PEP/LVET ratio, a/H per cent ratio, and A2O interval were significantly increased and LVET decreased in the diabetic group. QS2I, PEPI, and RFW did not differ from that in the normal group. Twenty-three per cent of patients had an abnormal systolic time interval, 54 percent an abnormal diastolic time interval, and 23 per cent had both abnormal intervals. Though these studies provide no difinite evidence of a cause, the abnormalities found may reflect a subclinical diabetic cardiopathy.

Adult↗
PubMedDate not supplied

[Blood pressure and blood lipids in normotensive patients with diabetes mellitus type I with microalbuminuria].

The study involved 50 normotensive men (means age = 34 years) with diabetes mellitus type I (mean duration of the disease 14 years). Group I included 29 patients with normal albumin excretion with the urine (UAE below 30 mg daily), and group II-21 patients with microalbuminuria (UAE 30-300 mg daily). Both groups were similar in relation to the age and duration of diabetes mellitus. Blood cholesterol was significantly higher in patients of group II than in patients of group I (p = 0.02) similarly to blood triglycerides levels (p = 0.01). Mean arterial pressure was lower in patients of group I than that in patients of group II (94.3 +/- 7.0 vs 99.1 +/- 6.0 mm Hg; p = 0.01). HbA1c was positively correlated with blood cholesterol (p = 0.01) and blood triglycerides levels (p = 0.05).

Adult↗
PubMedDate not supplied

[Evaluation of mental status of patients with diabetes mellitus type 1 in relation to the duration of the illness].

Personality features of 38 men (mean age 31 +/- 7 years) with the diagnosis of the type I diabetes mellitus and 23 healthy subjects of similar age were assessed by MMPI. Diabetics in addition were examined by means the Potential Intelligence Test (TPI). MMPI profiles of three groups of the examines were significantly different and suggested that the circumstances of diabetes mellitus type I and the duration of the disease could be responsible for the changes in the mental state of the patients.

Adult↗
PubMedDate not supplied

[Analysis of the cause of death in diabetic ketoacidosis based on 5 years of personal observation].

The authors observed 53 cases of diabetic ketoacidosis treated with low doses of insulin. Mean age of the patients was 41 +/- 17 years, duration of diabetes mellitus 7.5 +/- 6.4 years. Ketoacidosis was due to: infections in 36%, other diseases in 7%, and cessation of insulin therapy in 25% of cases. Ketoacidosis was a first sign of diabetes mellitus in 19% of cases while causative factor was not detected in 13% of cases. At the admission to hospital mean blood pH was 7.02 +/- 0.15, mean bicarbonate concentration 6.17 +/- 3.45 mM/l, and glycaemia 40.6 +/- 16.8 mM/l. Therapy of ketoacidosis was complicated by hypopotassemia in 1 patient and transient hypoglycaemia in another patient. Five patients (9.6%) died. Infections, myocardial infarction, acute pancreatitis, pulmonary edema, and disseminated intravascular coagulation were the causes of deaths.

Adult↗
PubMedDate not supplied

[Clinical examination of diabetic patients treated with monocomponent insulin manufactured by MP Polfa].

An effect of replacing conventional forms of insulin by the monocomponent insulin manufactured by "Polfa" was studied in the group of 22 diabetics. The patients were followed up for 12 months. An effect of monocomponent insulin on daily requirement of insulin, levels of anti-insulin, monocomponent and pancreatic peptide antibodies, compensation of diabetes mellitus, and lipodystrophy were investigated. New insulin preparation decreased anti-insulin and pancreatic peptide antibodies level and markedly diminished lipodystrophy. However, daily insulin requirement, degree of diabetes mellitus compensation, and anti-proinsulin antibodies level remained unchanged.

Adult↗
PubMedDate not supplied

[Renal hemodynamics in patients with short-lasting diabetes mellitus type I].

Parameters of renal hemodynamics have been determined in 30 male patients with diabetes mellitus, lasting for 1-24 months (mean 0.9 +/- 0.7 year), and in 19 healthy men of the same age. Patients' age ranged from 17 to 33 years (mean 27.5 +/- 5.0). All examined subjects have been normotensive (according to WHO criteria). Glomerula filtration rate with the aid of 51CrEDTA, and ERPF with 125I-hippurate have been determined. Mean GFR values have been significantly higher in diabetics than that in healthy men (142.9 +/- 29 vs 118 +/- 20 ml/min per 1.73 m2). Hyperfiltration (GFR over 140 ml per minute) has been found in 15 patients (50%). ERPF has also been higher in diabetic patients (929.2 +/- 230 vs 821.5 +/- 192 ml/min). This difference has been insignificant. No correlation between arterial blood pressure and GFR, ERPF, filtration fraction (FF), and RVR has been found.

Adult↗
PubMedDate not supplied

[Enalapril in patients with diabetes mellitus type I with microalbuminuria without hypertension].

The studies included 18 normotensive patients with diabetes mellitus type I (mean age 29 years) and constant microalbuminuria (UAE-30 - 300 mg/24 hours). Group A consisted of 10 patients treated with enalapril, and group B--10 patients given placebo. Glomerular filtration rate, ERPF, and UAE were measured before and after 6 months of therapy. UAE decreased significantly in patients of group A (p = 0.02) after 6 months while evident proteinuria was seen in two patients of group B. Arterial blood pressure dropped in patients of group A (131/84 vs 122/78 mm Hg), and increased significantly in patients of group B (126 +/- 8 vs 136 +/- 15 mm Hg; p < 0.05). Blood flow through kidneys improved (p = 0.02) and renal vascular resistance decreased (p = 0.02) in patients of group A. The obtained results suggest that enalapril may prevent diabetic nephropathy in diabetics with constant microalbuminuria.

Adult↗
PubMedDate not supplied

The clinical course of untreated asymptomatic bacteriuria in diabetic patients--14-year follow-up.

The present study aimed at accessing the natural history of untreated asymptomatic bacteriuria in diabetic patients observed for 14 years. Two groups of diabetic patients were examined. Group I comprised 53 patients with significant bacteriuria, without clinical symptoms of urinary tract infection. Group II consisted of 54 patients with sterile urine. All patients were clinically and bacteriologically examined every 3-6 months for 14 years. The results obtained in this study have proved that clinical symptoms of acute pyelonephritis occur with similar frequency in both groups (group I-6, group II-5 cases). No deterioration of kidney function was found. Arterial hypertension did not differ significantly in both groups at the beginning and end of the follow-up. The usefulness of antibacterial treatment of asymptomatic bacteriuria in diabetic patients is not adequately documented.

Adult↗