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Biomedical subjects

E Seifert

Publications and source records attributed to E Seifert.

At least 145 records · Page 8Linked to original sources
PubMed1976

[The accuracy of radiological and endoscopic examinations in the diagnosis of carcinoma of the stomach (author's transl)].

The accuracy of radiology in the diagnosis of gastric carcinomas was checked on 232 cases, including 24 early examples. Accuracy depends most of all on the experience of the radiologist. Amongst 146 patients, using a satisfactory technique, a carcinoma was diagnosed in 131 patients (90%) and suspected in eight (6%). In five (3%) the changes were misinterpreted as being benign and the lesion was missed in two (1%). Of 120 gastric carcinomas submitted to operation a correct diagnosis had been made radiologically in 88% and suspected in 4%; endoscopically, the diagnosis was made in 92% and suspected in 2%. Of the 24 early carcinomas, both methods suggested the presence of a malignant lesion in 80%. The combination of radiology, endoscopy, hitology and cytology increases accuracy to 95%. These results indicated that localised changes in the gastric mucosa and the wall of the stomach can be demonstrated only by using refined radiological techniques; each lesion should be confirmed by endoscopy and histology.

Diagnostic Errors↗
PubMed1976

[Clinical aspects of inflammatory diseases of the large bowel with reference to coloscopy (author's transl)].

Ulcerative colitis and regional colitis Crohn are the most frequent inflammatory diseases of the large bowel in Europe. Clinical differentiation of these disorders are difficult. Diarrhoe with bloody stools are predominant. In cases with Morbus Crohn anorectal fistulas and involvement of the terminal ileum are frequently found. In cases with ulcerative colitis anorectal fistulas are more rare but in this disease a carcinoma of the colon often develops, especially when the course is severe and the involvement of the colon is extended. Clinical symptoms, courses and complications of both diseases are described. In differential diagnoses endoscopic procedures especially coloscopy play an important role. In cases of ulcerative colitis about 90% the rectum is involved. Spontaneous haemorrhage of the colonic mucosa with edema and pseudopolyps are typical endoscopic findings. Most cases with Crohn's disease show flat and irregular ulcers within a normal mucosa. In later stage a "cobble stone" relief is demonstrable. Endoscopy and guided biopsy are not only important for differential diagnosis but also for treatment and prognosis.

Colitis, Ulcerative↗
PubMed1976

[Diagnostic procedures in congenital dilatation of the bile ducts (author's transl)].

A report is given of 29 cases with congenital dilatation of the bile ducts, and the value of different diagnostic procedures is discussed. Histology in combinations with clinical symptoms allows the diagnosis in cases with microhamartoma or with congenital fibrosis of the liver. Sonography is the most important procedure in the diagnosis of cysts of the liver (solitary cysts or polycystic conditions); it may be complemented by peritoneoscopy if diagnosis cannot be established with certainty by echogramm. If segmental dilatation of intrahepatic bile ducts (Caroli's disease) is suspected, intravenous cholangiography ought to be the first diagnostic step. A more reliable diagnostic procedure is endoscopic retrograde cholangiography (ERC) in theses cases; if ERC does not help, percutaneous transjugular cholangiography may be indicated. In establishing the diagnosis of cysts of the choledochus and of intra- plus extrahepatic dilatations of the bile duct systems sonography ought to be used in the first place; the method of choice in these latter conditions however is the ERC.

Bile Ducts, Intrahepatic↗
PubMed1975

[Early gastric carcinoma].

The early gastric cancer can now be diagnosed more frequently by improved methods of roentgenology and endoscopy. At present 16.7 percent of the gastric resections for cancer in our clinic are for early gastric cancers. Indicative clinical symptoms were demonstrable in 25 of our own 27 cases described here. Infiltration of the gastric wall (mucosa- and submucosatype) and lymph-node metastases are important to the prognosis. Intraoperatively, it is essential to localize the tumor unobjectionably and to perform a sufficiently radical resection (generally subtotal gastrectomy and excision of the lymph-nodes). The 5-year-survival-rate totals 70 to nearly 100 percent. Postoperatively controls are necessary for the diagnosis and eventually the treatment of possible recurrence.

Adult↗
PubMed1975

Gastric polypectomy.

In 138 patients of 215 gastric polyps were removed by electroresection through a fiberscope and the polyps recovered in toto by suction or special grasper-forceps. Discepancies of histological findings in the biopsy specimens and in the tissue of the whole polyps were often found. Follow-up examinations of the cases were presented. Based on our experiences a new histological classification of gastric polyps is neccessary.

Adenoma↗