Biomedical subjects

E Segenreich

Publications and source records attributed to E Segenreich.

39 records · Page 3Linked to original sources

PubMedDate not supplied

Andrological parameters in patients with varicocele and fertility disorders treated by high ligation of the left spermatic vein.

The results of surgical treatment of 50 subfertile patients with left varicocele are presented. Improvement of the spermiogram was noted as follows: 70% of patients had improvement of semen count, 48% of semen motility and 69.4% in the morphological pattern of spermatozoa. Pregnancy occurred in 50% of patients' wives. Eighty-four percent of the pregnancies took place during the first 12 months after the operation. A direct correlation was observed between the size of the varicocele and the number of pregnancies. Severely oligozoospermic patients with sperm count less than 10 million per milliliter semen constituted 72% of the men whose wives became pregnant. There was no statistically significant change after the operation in levels in the semen of luteinizing hormone, follicle stimulating hormone, testosterone and prolactin.

Adult↗

PubMedDate not supplied

Hyaluronidase activity in split human semen.

Hyaluronidase is an acrosomal enzyme which participates in the dissolution of the cumulus oophorus matrix, containing hyaluronic acid, and is essential for the fertilization process. In this study hyaluronidase activity was determined in two fractions of split normozoospermic and oligozoospermic human semen. The method consisted of measurements of areas of digestion of hyaluronic acid in agar (Petri dishes) as compared to activity obtained by commercial testicular hyaluronidase. It was found that the first splits of semen, which are generally characterized by higher sperm density and better quality of sperm, exhibit higher enzyme activity (136.0 +/- 11.6-207.0 +/- 15.1 micrograms/mL) as compared to the second splits (117.8 +/- 10-134.0 +/- 12.9 micrograms/mL).

Humans↗

PubMedDate not supplied

The evaluation of routine andrological parameters in human serum.

A study was carried out to evaluate the andrological parameters in 540 human semen specimens divided into groups according to sperm counts. The parameters were: motility percentage and grade, percentage of viability and of morphologically normal sperm and immature cells. The Duncan multiple range test and the Kruskal-Wallis test with multiple comparison of ranks were used in the statistical analyses. Of particular interest, among other our findings, were the significant differences obtained by comparing the group with sperm counts up to 5 x 10(6) per ml semen and that with counts ranging from 5.1 to 10 x 10(6) per ml semen. This was true for all parameters with the exception of semen volume. Comparison of the oligozoospermic groups (up to 20 x 10(6)/ml) with those having higher sperm counts also showed significant differences. There was a trend towards improvement of the examined parameters with the increase in sperm density, but with a remarkable heterogeneity particularly within the oligozoospermic groups. In all groups motility, viability and morphological normality of sperm showed a positive correlation with each other. "Normal values" of the parameters studied could be derived from scatterplot charts over the entire range of sperm counts and from the statistical evaluation of the grouped material.

Humans↗