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Biomedical subjects

E Schumann

Publications and source records attributed to E Schumann.

At least 19 recordsLinked to original sources

Sex-linked AFLP markers indicate a pseudoautosomal region in hemp ( Cannabis sativa L.).

In dioecious plants of hemp ( Cannabis sativa L.), males are regarded as heterogametic XY and females as homogametic XX, although it is difficult to discriminate the X cytologically from the Y. The Y chromosome is somewhat larger than the X. Our aim was to analyse AFLP markers on X and Y, and to use them to gain some insight into the structure of the sex chromosomes. Markers located on the sex chromosomes can be grouped into different classes, depending on the presence or absence of a fragment on the X and/or the Y. They are detected by separately analysing male and female progenies of a single cross. Five markers were found to be located on both chromosomes. A few recombinants were observed for marker pairs of this class in the male progenies. Two completely linked markers located on the Y chromosome in the male parent show a recombination rate of r = 0.25 with sex. Recombination must have occurred between the sex chromosomes in the male parent. The recombination analysis led to the conclusion that there is a pseudoautosomal region (PAR) on the sex chromosomes, allowing recombination between the X and the Y chromosome. The other regions of the sex chromosomes show only a few recombination events, for the Y as well as for the X. These results are discussed in comparison to other dioecious plants.

Cannabis↗

[Comparative studies of the rate of restenosis after implantation of Palmaz-Schatz and AVE-Micro stents].

Late results of interventional procedures utilizing coronary stents are largely determined by the rate of restenosis. So far few data are available addressing the effect of stent design, implantation pressure and morphologic factors on this crucial variable. Therefore we analyzed the coronary angiograms obtained in 259 patients before, immediately after and at 3 to 6 months following stent implantation for obstructive coronary disease. A total of 196 AVE-Micro-Stents and 142 Palmaz-Schatz-Stents were implanted into 307 stenoses. In 126 stenoses there were implanted only Palmaz-Schatz-Stents, in 170 only AVE-Micro-Stents and in 11 stenoses there were implanted Palmaz-Schatz- as well as Micro-Stents. Restenosis was defined as an over 50% stenosis at follow up. No significant difference was detected with regard to global restenosis rate at an average of 4 months following implantation (Palmaz-Schatz 33%, Micro-Stent 27%). If results were analyzed according to implantation pressure however, there was a significantly lower restenosis rate for AVE-Micro-Stents implanted with > 10 atm (17%) as compared to < or = 10 atm (35%, p < 0.02) and as compared to Palmaz-Schatz-Stents (34%, p < 0.02), which were also implanted with high pressure over 10 atm. In addition to implantation pressure, vessel segment and morphology of stenosis proved to be important determinants of late results. In this series of patients the AVE-Micro-Stent compared favourably to the Palmaz-Schatz-Stent not only with respect to a significantly lower restenosis rate, when implanted with pressures > 10 atm, but also with regard to its superior flexibility and handling characteristics.

Aged↗

[Effect of a change in posture on the diurnal variations of fructosamine concentration in diabetic patients].

Daily profiles of blood glucose, HbA1c, total protein and fructosamine were measured in 10 diabetic patients and the factor fructosamine x 7/g total protein was calculated. Measurements were done at 4 a.m. to be sure that the patients were sleeping for some time, during the day and the following evening at 11 p.m., when the patients were lying again, so that the influence of orthostasis, the difference between bed rest and walking could be demonstrated. The blood glucose profile was typical whereas the HbA1c concentration was very stable and constant. Total protein and fructosamine increased significantly by orthostasis; the correction of fructosamine by total protein diminished the differences, but did not completely eliminate the effect of orthostasis. However, fructosamine should be corrected by the total protein concentration in order to increase the diagnostic value of the parameter.

Adolescent↗

[New instrument for blood glucose determination. Results of a clinical trial of the Reflocheck].

Reflocheck, a new microprocessor-regulated apparatus determining blood sugar levels was tested in six laboratories. In the range of 20-450 mg/dl the apparatus gave precise results (co-efficient of variance 0.8%-6.4%), in good agreement with results by the hexokinase method. Reflocheck is an accurate and reliable instrument for the measuring of blood glucose levels.

Blood Chemical Analysis↗

[Application of ROC analysis to evaluating different methods of skeletal scintigraphy. Description of a practicable method].

Various techniques producing similar information can be compared by the use of ROC analysis. A practical and quick method of ROC analysis, which is otherwise very time-consuming, has been described for comparing various types of skeletal scintigraphy. Data is obtained by means of a phantom and evaluated with the help of a scheme which requires only moderate computational facilities.

Bone and Bones↗

[Exposure technics for computed scintigrams].

The technique of making copies on radiographic films or on multiformat cameras from computer scintigrams, computer tomograms, digital radiographs or other similar digital images should be carefully studied in order to make the best use of the characteristics of the film. Contrast transfer was studied using a nuclear medicine camera computer system with registration on radiographic film. Possible difficulties in obtaining copies and a simple software arrangement are described, which would influence contrast transmission.

Absorptiometry, Photon↗

[Value of radiological diagnosis in the complex study of femur head necrosis in children. 1. Plain film and arthography in the framework of complex studies of femur head necrosis].

The results of complex investigations of case history, clinical methods, plain film radiology, laboratory findings, arthrography, histology, scintigraphy, and angiography give information of the picture of necrosis of the femoral head ossification center. Especially from the radiological diagnosis conclusions can be drawn for secondary prevention, diagnosis, prognosis, and therapy.

Adolescent↗

[Value of radiological diagnosis in the complex study of femur head necrosis in children. 2. Scintigraphic and arteriographic studies in the framework of the complex diagnosis of femur head necrosis].

101 scintigraphic investigations and 42 angiograms show that the vascular tamponade is the decisive factor for the beginning of necrosis of the femoral head ossification center. Plain films, scintigraphy and angiography give information of the duration of the disease. Extent and localisation of the circulatory disturbance are important for the prognosis of the disease. From stage classification and prognostic factors the conclusions for therapy can be drawn.

Adolescent↗

[Late arterial complications after radiotherapy].

Late effects of radiotherapy are observed more frequently due to the improved results of the treatment of cancer and the resulting longer survival times. The big arteries, however, are only seldom attacked by late complications. The authors present a single case and stress the importance corresponding therapeutic action.

Adult↗