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Biomedical subjects

E Schick

Publications and source records attributed to E Schick.

At least 37 records · Page 2Linked to original sources

Does urethral instrumentation affect uroflowmetry measurements?

Uroflowmetry was performed before and after urethral catheterisation in 129 patients. Uroflowmetry measurements were significantly modified by urethral instrumentation. In males, both maximum and mean flow rates decreased following urethral catheterisation, while in females only the maximum flow rate decreased, the mean flow rate remaining unchanged. Voided volume increased (and consequently residual urine decreased) in females after catheterisation, but did not change significantly in males. False positive results were encountered in 32% of patients and false negative results in 11% when flowmetry was done immediately after catheterisation. Uroflowmetry after urethral instrumentation is not recommended.

Adolescent↗

Pericardial pseudotumor. Echocardiographic observation of juxtacardiac pulmonary collapse.

Despite its value in the diagnosis of pericardial disease, two-dimensional echocardiography also is known to produce confounding results. Ten patients had juxtacardiac masses simulating pericardial tumor implants on echocardiographic examination ("pericardial pseudotumor") caused by juxtacardiac pulmonary atelectasis or lobar collapse. The atelectatic nature of these masses was based on echocardiographic delineation of pericardial and pleural anatomy, combined with ancillary radiographic and CT studies. Drainage of pleural fluid also led to disappearance of the masses on echocardiographic examination, suggesting that the masses were an ultrasonic manifestation of pulmonary atelectasis resulting from surrounding compressive effusive fluid. Finally, clinical follow-up failed to show development of malignant disease in any patient. The possibility of pericardial pseudotumor should be considered when ultrasound studies show juxtacardiac masses within large collections of pleural fluid, especially in the clinical absence of malignant disease.

Adult↗

Relevance of constipation to enuresis, urinary tract infection and reflux. A review.

Little attention has been afforded the relevance of constipation to urinary symptoms. Problems of definition and measurement have contributed to this problem. A review of the literature suggests that rectal dilatation may influence the function of the urinary tract leading to urinary tract infection and enuresis. Our studies indicate that constipation may, by causing uninhibited bladder contractions, cause urinary tract infection, enuresis and vesicoureteral reflux.

Child↗

Constipation a commonly unrecognized cause of enuresis.

Constipation was confirmed by history, rectal examination, and rectal manometric studies in 22 of 25 children with enuresis. Treatment of constipation resulted in resolution of enuresis. Uninhibited bladder contractions, observed in enuretic constipated children, were also noted in children with constipation alone, suggesting that constipation is a commonly unrecognized etiologic factor in enuresis.

Child↗

Constipation associated with vesicoureteral reflux.

Seventeen children who had vesicoureteral reflux underwent urodynamic and rectal manometric studies. All had uninhibited bladder contractions. All had rectal dilatation confirming the presence of constipation by rectal balloon manometry. The recurrent association of constipation with ureteral reflux suggests the possibility of a nonfortuitous association.

Child↗

Objective assessment of resistance of female urethra to stress. A scale to establish degree of urethral incompetence.

During urethral pressure profile (UPP) studies under gradually increasing stress, the maximum urethral closure pressure decreases. This observation led to a simple urodynamic test which allows the estimation of the maximum stress (intensity of cough) tolerated by the urethra before leakage begins. The determination of this critical pressure forms the basis of the urethral incompetence scale. The urethra of a female patient can be characterized by the amplitude of this maximum stress (in cm H2O) the urethra can handle and still remain continent. The cough intensity scale has been divided into 5 segments, defining 5 degrees of urethral incompetence. The critical pressure, which determines the degree of urethral incompetence is a constant value for a given patient, provided the bladder volume is kept constant and the position of the patient during the examination is unchanged. This method establishes the functional status of the female urethra as far as its sphincteric capabilities are concerned under different stress conditions. It represents the degree of pressure transmission from the abdominal cavity to the proximal urethra during stress. It evaluates objectively the functional results of different surgical or medical therapeutic modalities to cure genuine stress incontinence. It allows a better selection of patients with unstable bladder and genuine stress incontinence who will more likely benefit from a retropubic cystourethropexy.

Female↗

Effects of oxybutynin on vesicoureteral reflux in children.

We reviewed retrospectively 40 children seen from 1980 to 1984 with vesicoureteral reflux in 53 ureters. All patients had a hyperreflexic bladder on urodynamic evaluation with or without vesicoperineal dyssynergia but they were otherwise neurologically normal. All except 1 child received prophylactic antibiotics. Of the children 37 received oxybutynin therapy for bladder hyperreflexia for 3 to 18 months. Reflux disappeared or became grade I in 62.3 per cent of the ureters. Of the children manifesting urinary incontinence at the time of urodynamic study reflux disappeared or became grade I in 78.6 per cent. Reflux resolved or became grade I in 20 per cent of the children with no urinary incontinence. Of those patients with recurrent reflux at the onset of urinary incontinence and bladder instability reflux resolved or became grade I in 80 per cent. Oxybutynin therapy for hyperreflexic bladder resulted in an average increase in bladder capacity of 97 cc (54.2 per cent), which was maintained after cessation of treatment. These data suggest that bladder instability can be an important factor in causing and perpetuating reflux. Therapy aimed at decreasing intravesical pressure will enhance resolution or downgrading of reflux.

Child↗

Constipation, bladder instability, urinary tract infection syndrome.

Forty-seven children with recurrent urinary tract infection were noted to have large fecal reservoirs by rectal examination and rectal manometry. Constipation was accompanied in the majority by enuresis and/or encopresis. Urodynamic studies indicated uninhibited bladder contractions. Aggressive treatment of the constipation resulted in cessation of infection in 44 patients, enuresis in 22 of 32 patients and encopresis in 20 of 21 patients and an improvement in bladder function with cessation of all other forms of treatment.

Child↗

Malakoplakia of testis.

Two cases of malakoplakia of the testis are reported. Ultrastructural studies were performed in both cases and confirmed the histiocytic nature of the large cells seen in this granulomatous process. Characteristic Michaelis-Gutmann bodies are identified in those macrophages and seem to originate from altered lysosomes. From these observations and a review of the literature, the possible physiopathogenesis of the disease is summarized, and comments are made on the treatment of malakoplakia.

Adult↗

Central nervous side effects following ifosfamide monotherapy of advanced renal carcinoma.

Ten patients with advanced renal carcinoma were treated by ifosfamide (50-60 mg/kd/day x 5 days). The treatment was repeated every 4 weeks and continued until progression appeared. Two patients came into partial remission, two had subjective improvement, and six did not respond. Seven patients developed acute psychopathological symptoms during the first ifosfamide-cycle. Five patients had visual and paranoid hallucinations, four patients were completely confused. Follow-up for up to 10 weeks showed a persisting organic brain syndrome in five patients.

Adult↗

Inverted papilloma of urinary tract.

The inverted papilloma of the urinary tract is a rare tumor; few urologists and pathologists are aware of its existence. Even if the histogenesis of the lesion is unknown, the correct diagnosis is essential, since its behavior appears totally benign, contrary to transitional cell carcinoma. We report 3 new cases, one originating in the renal pelvis, and one in an eighteen-year-old woman.

Adolescent↗

[Surgery for priapism (author's transl)].

UNLABELLED: The authors review the literature with regard to surgery for priapism performed in 138 patients: 92 treated by uni- or bilateral sapheno-cavernous anastomosis and 46 by spongio-cavernous shunt. Sapheno-cavernous anastomosis: in 92 cases operated upon, there were 65 useable records. Conservation of potency in 61.5% of cases (40 out of 65) in particular in young patients aged 40 years or less where the rate of conservation of virility was 73.8%. After the age of 40, this rate fell to 39.1% of cases. It was surprising to note that the results were similar whether the operation was performed during the first 48 hours or later. Results were better after unilateral anastomosis (72.5% of cases with conservation of erection), than after bilateral surgery (54.5% conservation of erection). COMPLICATIONS of this type of surgery consisted of pulmonary embolism and necrosis of the penis. Spongio-cavernous anastomosis: 42 published cases but only 32 useable. Overall, 62.5% of cases with conservation of erection. Results were better before the age of 40 (70% success) than in older patients (50% success). Once again, the functional result obtained was independent of the period for which priapism had been present preoperatively. COMPLICATIONS: urethrocutaneous and urethro-cavernous fistulae. Comparison of the two types of operation failed to reveal any difference before the age of 40 years. By contrast, after 40 spongio-cavernous anastomosis gave slightly superior results (50% as against 39% for sapheno-cavernous anastomosis). On the basis of this general review, the authors drew a more favourable impression of caverno-spongious anastomosis.

Adult↗