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Biomedical subjects

E S Rosen

Publications and source records attributed to E S Rosen.

At least 19 recordsLinked to original sources
PubMed2001

What is LASIK?

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Corneal Stroma↗
PubMed2001

Binocular vision?

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Cataract↗
PubMed2000

Refractive lensectomy for hyperopia.

PURPOSE: The purpose of this study was to evaluate refractive lensectomy as a surgical procedure for the treatment of hyperopia. DESIGN: A retrospective noncomparative case series. PARTICIPANTS: Twenty-nine patients were included in the study. Fifty eyes underwent extraction of the crystalline lens and intraocular lens implantation. METHODS: Operations were performed by the same surgeon with the patient under general anesthetic. All lenses were removed by phacoemulsification with insertion of lens implants singly or as piggyback lenses. The Holladay2 formula was used to calculate lens powers. Results are compared with other methods of treating hyperopia. MAIN OUTCOME MEASURES: The main parameters assessed were safety, efficacy, predictability, stability, and complications. RESULTS: Eyes were divided into group A (n = 26), with an average preoperative spherical equivalent (SE) of +2.26 +/- 0.94, and group B (n = 24), with an average preoperative SE of +6.32 +/- 1.32. In group A, after refractive lensectomy, 80.7% had no change in best-corrected visual acuity (BCVA) or gained a line, whereas 11.5% lost one line; 88.5% had an uncorrected visual acuity (UCVA) of 20/40 or better, and 88.5% were within 1 diopter (D) of intended postoperative SE. In group B, 70.9% of eyes had no change or gained a line in BCVA, whereas 29.2% lost a line of BCVA; 62.5% had UCVA of 20/40 or better postoperatively, and 58.3% were within 1 D of the intended SE. In one eye the posterior capsule was breached intraoperatively. One eye had a symptomatic episode of cystoid macula edema that settled spontaneously. To date, seven eyes have required secondary refractive procedures, and three eyes have required yttrium-aluminum-garnet capsulotomy. CONCLUSIONS: In the presbyopic age group refractive lensectomy may be a realistic alternative to photorefractive keratectomy or laser in situ keratomileusis, with certain potential advantages.

Female↗
PubMed2000

LASIK mania.

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Cornea↗
PubMed2000

Never say never.

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Cornea↗
PubMed1994

Back pain in ophthalmologists.

A questionnaire regarding the working practices and incidence of back pain was sent to all 498 consultant ophthalmologists in the United Kingdom. Three hundred and twenty-five (65.3%) questionnaires were analysed by time spent in speciality, and time spent operating each week. One hundred and seventy-four ophthalmologists (54%) had significant attacks of back pain, with the longest-serving consultants having an increased incidence. The number and duration of acute attacks increased with years in speciality but was unrelated to time spent operating. Treatment included analgesics in 97 (56%), physiotherapy in 40 (23%), and 'alternative' medical treatment including osteopathy and chiropraxy in 14 (8%); no treatment was needed in 56 (32%). Investigation and treatment increased with years spent in speciality, 49 (28%) seeking medical advice, usually from a specialist, and 69 (39%) requiring further investigations including plain radiographs, CT scans, myelograms and MRI scans. Nine surgeons needed surgery for back pain.

Back Pain↗
PubMed1993

Intraocular lenses.

Significant advances in intraocular lens designs have not been over the last year. The lack of successful lens implant designs to match the requirements of small-incision cataract surgery is frustrating. Although it is possible to comfortably remove the crystalline lens through a 2.7-mm incision, this incision inevitably has to be enlarged to accommodate even the most malleable lens implant available. Polymethyl methacrylate remains the preferred lens material for most surgeons, but silicone lens implants have gained consideration and have incited controversy. Acrylic polymers are in the early stages of clinical evaluation. Phakic lens implants for high myopia remain controversial while longer-term evidence for the safety of renewed designs is gathered.

Biocompatible Materials↗
PubMed1990

Oral fluorescein angiography: reassessment of its relative safety and evaluation of optimum conditions with use of capsules.

Injection of fluorescein intravenously for fundal angiography is associated with a high incidence of minor adverse effects (21%) but a very low incidence of serious (life threatening) reactions (0.05%). A serious reaction may occur without warning in a patient with no history of atopy. There are no reports of oral fluorescein causing a serious reaction, and minor adverse effects are uncommon. A study was undertaken to determine optimum conditions for oral fluorescein angiography. Capsules proved more convenient than a solution for ingestion of fluorescein. A dose of 25 mg/kg body weight produced good quality angiograms in 75% of the patients. The best pictures were obtained by photographing the fundus after 40 and 60 minutes.

Administration, Oral↗
PubMed1989

The blood-retinal barrier in chloroquine retinopathy.

Chloroquine retinopathy can result in devastating loss of vision. To date, there are no effective and reliable methods of detecting the toxicity at an early stage when retinopathy may be reversible. Chloroquine is deposited in the retinal pigment epithelium, which forms part of the blood-retinal barrier (BRB). By vitreous fluorophotometry we have shown that there is breakdown of the BRB in chloroquine retinopathy. However, in asymptomatic patients who had received varying amounts of hydroxychloroquine (up to 1067 g), the BRB remained intact.

Aged↗