A 14-year-old adolescent girl presented with a 2-year history of an exquisitely tender, vegetating cheilitis. Because of this, she was unable to drink fluids and was repeatedly hospitalized for dehydration and pain management. Lip and skin biopsies, as well as multiple laboratory studies did not support a definitive diagnosis. After 2 years, a diagnosis of factitial cheilitis was finally established.

Adolescent↗

PubMedDate not supplied

Antiorthostatic suspension stimulates profiles of macrophage activation in mice.

The antiorthostatic suspension model simulates certain physiological effects of spaceflight. We have previously reported BDF1 mice suspended by the tail in the antiorthostatic orientation for 4 days express high levels of resistance to virulent Listeria monocytogenesinfection. In the present study, we examined whether the increased resistance to this organism correlates with profiles of macrophage activation, given the role of the macrophage in killing this pathogen in vivo. We infected BDF1 mice with a lethal dose of virulent L. monocytogenes on day 4 of antiorthostatic suspension and 24 h later constructed profiles of macrophage activation. Viable listeria could not be detected in mice suspended in the antiorthostatic orientation 24 h after infection. Flow cytometric analysis revealed the numbers of granulocytes and mononuclear phagocytes in the spleen of infected mice were not significantly altered as a result of antiorthostatic suspension. Splenocytes from antiorthostatically suspended infected mice produced increased titers of IL-1. Serum levels of neopterin, a nucleotide metabolite secreted by activated macrophages, were enhanced in mice infected during antiorthostatic suspension, but not in antiorthostatically suspended naive mice. Splenic macrophages from mice infected on day 4 of suspension produced enhanced levels of lysozyme. In contrast to the results from antiorthostatically suspended infected mice, macrophages from antiorthostatically suspended uninfected mice did not express enhanced bactericidal activities. The collective results indicate that antiorthostatic suspension can stimulate profiles of macrophage activation which correlate with increased resistance to infection by certain classes of pathogenic bacteria.

Aerospace Medicine↗

PubMedDate not supplied

Sperm transmigration as a cause of ectopic pregnancy.

This case represents the phenomenon of contralateral sperm transperitoneal migration: sperm gaining access to the left oviduct after entering the peritoneal cavity via the right oviduct. The ovum from the left ovary after being successfully fertilized could not be transported into the uterine cavity due to the previous segmental resection, ultimately resulting in an ectopic pregnancy.

Adult↗

PubMedDate not supplied

Reactions to intravenous pyelography contrast media.

Reactions to contrast media used for intravenous pyelography are everyday possibilities in a radiology department, and statistics indicate that the incidence of fatalities has increased after a period of decline. The physiology of reactions and how to be prepared for them, as described here, are important parts of the technologist's knowledge.

Anaphylaxis↗

PubMedDate not supplied

51 Cr-polyphosphates: their general behaviour in normal and tumor bearing animals.

Explore the source record for details and available documents.

Acid Phosphatase↗

PubMedDate not supplied

Vaginal birth after cesarean: a 5-year experience in a family practice residency program.

BACKGROUND: The national health objective for the year 2000 is to have an overall Cesarean section rate of 15 percent, a primary Cesarean section rate of 12 percent, and a vaginal birth after Cesarean (VBAC) rate of 35 percent. The current national statistics for the most recent year available, 1991, are 23.5 percent, 17 percent, and 24.2 percent, respectively. This study evaluates a VBAC program at a community-hospital-based family practice residency program. METHODS: This study was a retrospective chart review of 996 family practice service deliveries from 1988 to 1992. RESULTS: Of the 98 patients who had a previous Cesarean section, 87 patients (89 percent) were eligible for a trial of labor. Fifty-six patients (64 percent) accepted a trial of labor and 31 patients (36 percent) refused. The overall Cesarean section rate was 15 percent, the primary Cesarean section rate was 11 percent, the VBAC rate was 44 percent, and the successful VBAC rate was 77 percent. CONCLUSION: We report a successful VBAC program at a community-hospital-based family practice residency program.

Adolescent↗