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Biomedical subjects

E Rupprecht

Publications and source records attributed to E Rupprecht.

At least 73 records · Page 4Linked to original sources

[Pathogenesis of osteopathy caused by anticonvulsives (author's transl)].

After a short survey of the recent suggestions of the pathogenesis of osteopathy caused by therapy with anticonvulsives it is demonstrated in the light of 3 case reports that 1. A vitamin D-sensible rickets, which is only due to abnormal living conditions, can develop in severely cerebral-damaged persons if there is no specific vitamin D administration. 2. An "antiepileptic rickets" is spontaneously reversible if the anticonvulsive therapy is stopped. 3. An enzymatic induction due to anticonvulsives is also detectable in the light of morphologic hepatic changes (biopsy, electron microscopy). Hence it follows that there are demands for a specific control of all patients treated with anticonvulsives. It is recommended to carry out a rickets prevention for a selected patient group.

Anticonvulsants↗

Comparative assessment of clinical, roentgenological and anatomicopathological pulmonary findings in prematures and newborns.

The clinical, roentgenological and pathologicanatomical findings in 101 deceased premature and newborn infants, delivered in the years 1968-1971, have been studied by transferring the data on to punch cards for the purposes of comparison and analysis. A full or partial conformity of the X-Ray findings with the pathologic-anatomic diagnosis was found in 72 cases. It has been concluded that a distinct radiomorphologic substrate is often caused by a combination of various pathologic-anatomical changes.

Auscultation↗

[Epidemiologic and bronchologic aspects of chronic bronchitis in childhood (author's transl)].

After establishing a suitable definition of chronic and relapsing bronchitis in childhood in the G.D.R. in 1969 corresponding epidemiologic studies carried out in school beginners and school children in Dresden revealed a prevalence rate of 1,64% to 3,06% for this disease. The analysis of bronchologic examinations of 274 children performed at the Pediatric Clinic of the Medical Academy Dresden during the last four years showed a deforming bronchitis as the most frequent finding in the bronchogram of 51% of the patients. Malformations of the tracheobronchial tree could be demonstrated in 16% of the children examined. The frequency of bronchiectases was at a very low level (9%) and showed a regression by the half as compared with former results. The results of bacteriological examinations of the bronchial secretion, quantitative analyses of the immune globulins in the serum and the bronchial secretion and the alpha-1-antitrypsin are discussed as causative factors for chronic and relapsing bronchitis in childhood. For assessing the prognosis of deforming bronchitis 220 children had a bronchologic follow-up examination in four bronchologic centers for children in the G.D.R. after a one or several years' dispensary treatment. An improvement or a normalisation of the findings could be demonstrated by means of the bronchogram in 62% of these patients, whereas a deterioration or a transition to bronchiectases was observed in only 22% of the patients.

Adolescent↗