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Biomedical subjects

E Rudzki

Publications and source records attributed to E Rudzki.

At least 145 records · Page 8Linked to original sources
PubMed1976

Sensitivity to some rubber additives.

The frequency of positive patch tests to 13 rubber accelerators in Poland was recorded. Of particular interest was the relatively large group of patients positive to several, mostly chemically unrelated, accelerators. The mechanism of this multiple sensitivity is discussed. Positive tests to N-isopropyl-N-phenyl-p-phenylenediamine were observed in more than half of the patients reacting to several aromatic amines. Anamnesis indicated that in the case of cross-reactions to many aromatic amines, none of the patients positive to N-isopropyl-N-phenyl-p-phenylenediamine had complained of a reaction to rubber products.

Age Factors↗
PubMed1976

Sensitivity to epoxy resins and triethylenetetramine.

The present studies concerned 31 work sites in eight factories at which 422 persons were employed. In the course of seven years there were 126 cases of dermatitis, 99 of whom were patch-tested. Positive reactions to epoxy resin and/or to triethylenetetramine were found in 65.7% of the subjects. The aetiology of the other cases is discussed. Some of the patients who were positive to epoxy resin were tested with Bisphenol A and modified resins with blocked epoxy groups. The latency period of dermatitis and the localization were recorded, as well as the influence of the season and of certain working conditions on the occurrence of sensitization. Of the 80 patients who changed their occupation, there were relapses in 50 within one year. Relapses were more frequent in persons who continued to work with epoxy resins for more than three months after the appearance of dermatitis and in those simultaneously sensitive to allergens in the standard series.

Dermatitis, Contact↗
PubMed1976

Sensitivity to 35 essential oils.

Two hundred consecutive patients and 50 subjects positive to balsams were tested with the 35 essential oils most frequently used in Polish cosmetics. The frequency of sensitivity to the particular oils is noted and the index of sensitization calculated as the amount of oil/kg used annually for the production of Polish cosmetics per one patient positive to this oil. The correlation of positive tests to essential oils with positive tests to four balsams of the standard series is shown.

Balsams↗
PubMed1976

Sensitizing and irritating properties of star anise oil.

Star anise oil in 2 and 1% concentrations produced active sensitization in 5% of test subjects, and positive patch tests in 36 and 34%, respectively, of consecutive patients with dermatitis. A comparison of the results of tests with balsams and other essential oils showed that star anise oil does not give cross-reactions and pseudo cross-sensitivity. Patients positive to this oil are frequently positive to anethole and to other constituents of this oil: alpha-pinene, limonene and safrole. In tests with star anise oil it is noteworthy that a 1% concentration is strongly irritant, and 0.5% reveals sensitivity in only one fifth of the actively sensitized subjects. It is possible that the cause of false negative patch tests might be similar in the case of some other allergens.

Allergens↗
PubMed1976

Patch tests with potassium dichromate removed after 24 and 48 hours.

The rate of release in vitro of four potassium dichromate concentrations (0.5, 0.1, 0.05 and 0.01%) was determined. In the course of 24 h, 90.1-97.5% was released of the total K2Cr2O7 amount in 48 h. Out of 30 patients positive to 0.05% dichromate when the patch test was done routinely, 29 were also positive when the patch was removed after 24 h. The effect of the earlier removal of the patch test was also noted in seven other patients, when results of tests with lower dichromate concentrations were taken into account.

Allergens↗
PubMed1976

Cross-reactions between ethylenediamine, diethylenetriamine and triethylenetetramine.

A consecutive series of 1544 patients and 137 patients in occupational contact with epoxy resins were tested with ethylenediamine and/or triethylenetetramine; some were tested with diethylenetriamine. Guinea pigs sensitized to triethylenetetramine were tested with ethylenediamine and diethylenetriamine. The results showed that cross-reactions may occur between triethylenetetramine and ethylenediamine, although the majority of the patients were sensitized to only one of the compounds.

Allergens↗
PubMed1976

Occupational contact dermatitis in 100 consecutive patients.

One hundred consecutive cases of occupational contact dermatitis diagnosed in Warsaw are discussed. In 79 subjects allergic and in 21 patients irritant occupational dermatitis was found. The most numerous group were workers employed with epoxy resins (20 persons), next came masons (14 subjects), and third medical staff members (12 persons). In 46 patients the standard series was sufficient for diagnosis of allergic occupational contact dermatitis, but in thirty three cases it was indispensable to test them with additional subsances.

Construction Materials↗