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Biomedical subjects

E Rosskamp

Publications and source records attributed to E Rosskamp.

12 recordsLinked to original sources
PubMed1997

[Polychlorinated biphenyls indoors: attempt at an assessment].

The use of products containing PCB in buildings resulted in indoor air contaminations. The search for appropriate measures is hampered by several different uncertainties in the regulatory toxicological process. These refer to problems in exposure assessment including measurement approaches, the toxicological evaluation of health risks including the derivation of a tolerable intake and the use of TCDD toxicity equivalency factors and finally the legal consequences of health risk evaluation. Since no consensus on these aspects has been achieved, the regulatory consequences vary considerably from one German state government to the other. FAO/WHO have not been able to arrive at a satisfactory supranational recommendation of a tolerable intake for PCB.

Air Pollution, Indoor↗
PubMed1990

[Evaluation of humidifier units within the scope of room climate modification].

An analysis method was developed for detecting the biocides usually employed in German humidification units in air-conditioning plant to enable determination of air concentrations of methylisothiazalone often used in such plant (German trade names e.g. Kathon WT, Wacozid 3150, Lavisan Q). Results of measurements revealed great variations in isothiazolone concentrations in ambient indoor aerosols, the peak values being 3.4 micrograms/m3 air. The concentration of these compounds added to the water in the humidificator chambers was also measured in relation to the presence of microorganisms to find out the microbicidal action of the compounds. It was found that the isothiazolone concentrations varied greatly in course of time and that microbiology revealed in some cases a marked contamination of the water in the humidifiers with pathogens. Microbial analyses showed the presence of Legionella pneumophila and free amoeba, sometimes with very high aerobic colony counts. The measured data lead to the conclusion that it is possible that both the unsatisfactory hygienic status of many circulatory spray humidifiers and the exposure to the biocides contained in the humidifier fluids, may be responsible for some of the patterns of signs and symptoms known as "sick building" syndrome.

Air Conditioning↗
PubMedDate not supplied

[Dioxins and polychlorinated biphenyls in indoor areas].

Polychlorinated dibenzodioxins, dibenzofurans and polychlorinated biphenyls (PCB) today belong to the most significant and widespread contaminants. They are found in soil, sewage sludge, indoor and outdoor air, in food especially of animal origin as well as in breast milk. Based on available toxicological data the Federal Health Office and the Federal Office of the Environment suggested a tolerable daily intake (TDI) for PCB of 1-3 micrograms PCB/kg body weight in 1983 and for dioxins and furans of 1-10 pg TCDD toxic equivalents/kg body weight aiming at less than 1 pg equivalent in 1985. This allows for a risk assessment of indoor air pollution (for example in kindergartens, schools etc.). As a precaution the proportional daily intake of persistent environmental contaminants via indoor air should not exceed 10% of the TDI for longer periods. Step-by-step measures should be taken if there is any over stepping.

Air Pollutants↗