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Biomedical subjects

E Romano

Publications and source records attributed to E Romano.

At least 73 records · Page 4Linked to original sources
PubMed1985

Suppressive effect of iron on in vitro lymphocyte function: formation of iron polymers as a possible explanation.

The evidence presented here indicates that ferric citrate inhibits both the phytohemagglutinin-induced lymphocyte proliferation and the formation of E rosettes by T lymphocytes. These inhibitory effects are only observed in the presence of ferric citrate with a metal to ligand molar ratio of (1:1) but not with ferric citrate (1:20) or sodium citrate. Since ferric citrate (1:1) at a physiological pH tends to hydrolyze and polymerize, we suggest that the inhibitory effect is mediated by the formation of iron polymers.

Ferric Compounds↗
PubMed1981

Effect of cysteine on iron absorption in man.

Cysteine significantly increases, about 2-fold, the absorption from nonheme iron present in vegetable foods, hemosiderin, and of a ferric salt, when this amino acid is administered during the ingestion of foods. No enhancing effect was obtained when the amino acid was mixed with the food before the final cooking. A slight but significant enhancement of heme iron absorption was observed when a large dose of cysteine was administered during the ingestion of hemoglobin. This amino acid mimics the enhancing effect from proteins present in animal foods such as beef, lamb, pork, fish, chicken, and liver. It could be possible that proteins and cysteine share the same mechanism by which they induce an increase of iron absorption.

Absorption↗
PubMed1981

[The hemodynamic effects of reproterol in patients with chronic obstructive lung disease (author's transl)].

Our study was undertaken in order to evaluate hemodynamic effects of intravenous administration of Reproterol in patients with chronic obstructive lung disease (COLD). Reproterol is a monomulecolar combination of catecholamine and theophilline. Diastolic pulmonary pressure and wedge pressure decreased 20 minutes after Reproterol while total pulmonary resistances were reduced 10 minutes after drug administration; sistolic pulmonary pressure and cardiac index increased only after 10 minutes; heart rate increased until 15th minute. Reproterol, as a catecholamine-theophylline combination, has an additional site of action over and above the pure catecholamine effect owing to inhibition of phosphodiesterase; so an increase in cAMP content is achieved either by increasing the synthesis or by blocking the breakdown. Our results assess that Reproterol has a beneficial effect on pulmonary hemodynamics in COLD.

Adult↗
PubMed1980

Chlorpromazine and frusemide in treatment of acute left-ventricular failure.

Chlorpromazine, a phenothiazine derivative with central and peripheral vasodilating effect, was given intravenously, with frusemide, to five patients with acute pulmonary oedema who did not respond to conventional treatment. Four of the five recovered fully. Chlopromazine seems to be a suitable vasodilator for use in treating acute pulmonary oedema outside intensive-care units, since its use does not require monitoring by invasive techniques.

Acute Disease↗