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Biomedical subjects

E Reich

Publications and source records attributed to E Reich.

At least 199 records · Page 11Linked to original sources
PubMed1969

Stereochemical analysis of the specificity of pancreatic RNAse with polyformycin as substrate: differentiation of the transphosphorylation and hydrolysis reactions.

A stereochemical analysis of the substrate and inhibitor specificities of bovine pancreatic ribonuclease A is presented. A scheme is proposed in which the binding specificity for this protein-nucleic acid interaction is rationalized in terms of a simple system of H-bonds. The functional groups that govern substrate binding for transphosphorylation and hydrolysis, respectively, are considered and differentiated, and predictions are offered concerning the interaction of presumptive substrates with RNase.

Animals↗