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Biomedical subjects

E Rebohle

Publications and source records attributed to E Rebohle.

At least 37 records · Page 2Linked to original sources
PubMed1978

[Reproducibility of bronchial provocative testing in bronchitis (author's transl)].

Bronchial reactivity was examined every 3 month in a follow-up study of 40 subjects mostly showing chronic nonspecific lung disease and all having bronchial hyperreactivity at the beginning of the study. Only 7 of them (17.5%) had constant hyperreactivity for the time of observation. There has been parallelism between test results and complaints in 72% of patients with chronic bronchitis and in 65.2% of the second group (mostly subjects with bronchitis). Seasons had no strong influence on bronchial reactivity. Bronchial provocative testing has proved as a valuabel method for verification of obstructive complaints. The test results shouldn't be interpreted without regarding clinical data. Using as a screening test a more detailed diagnostic and follow-up are necessary to avoid false and premature consequences. As to expert opinions and decisions on compensation the test results can correctly be interpreted only if reproducibility in the single case has been proved and if they are in agreement with the clinical signs and symptoms of the case.

Acetylcholine↗
PubMed1977

[Evaluation of a bronchopulmonal screening program for the aims of occupational health in workers exposed to cement dust (author's transl)].

180 workers exposed to cement dust were examined in a bronchopulmonal screening including standardized history, clinical examination, spirometry and bronchial reactivity testing. The program proved to be suitable. The time needed for each person was 45 minutes. The workers have been selected in such a manner that the informational value of the methods of lung functional diagnostic could be verified in workers exposed to dust before manifestation of lung diseases. In view of individual diagnosis and rehabilitation bronchial reactivity tests lead to valuable information in workers exposed to cement dust. In the other hand no higher frequency of bronchial hyperreactivity in workers without lung diseases and exposed to dust could be proved. The rates of decrease of FEV1 after inhalation of acetylcholine, however, revealed a positive correlation to the duration of exposure.

Adolescent↗
PubMed1977

[Procedure of the bronchial provocation tests (author's transl)].

A procedure of bronchial inhalation challenge with acetylcholine accepted by the working group "Aerosols in Medicine" of the GDR on its session in autumn 1976 in Leipzig is reported. The decisions on substance, dose, kinds of application and interpretation are discussed and confirmed.

Acetylcholine↗
PubMed1976

[Formaldehyde sensitization in occupational respiratory exposure].

The determination in a total of 180 workmen regularly exposed to varying breathing zone levels of for-maldehyde of an index of sensitization as low as 12.2% may be interpreted to mean that formaldehyde exerts only a rather weak effect on the respiratory tract. It was not possible for allergoses to be clinically established even if consideration was given to technical difficulties encountered in the use of provocative tests conducted for diagnostic purposes. Rather, the conditions of exposure and the results of tests may be regarded as suggestion that the nonspecific symptomatology was produced by irritation. What is also of considerable importance in this connection is that extremely wide difference in individual sensitivity were observed.

Allergens↗
PubMed1976

[Frequency and importance of mold sensitization in bakery workers].

Mycological, allergological and immunological, as well as occupational-hygiene investigations were made in a large baking products plant in an attempt to find an answer to the questions as to whether allergic respiratory diseases produced in bakers by mold fungi may be considered occupational diseases. In addition, a retrograde analysis was made of a number of statements made by experts in occupational medicine for bakers, confectioners, and control persons. In the case of bakers, recognition as an occupational illness of an allergic respiratory disease caused by such mold fungi as Aspergillus and Mucor is fully justified in view of the agreement between the increased rate of sensitization of those exposed to the mentioned mold fungi and the results of extensive mycological tests. The results of occupational-hygiene investigations made using a specialized airborne dust sampler showed that bakers working in this large baking products plant were exposed to considerable amounts of dust. The results obtained also show that it is absolutely necessary for remedial measures to be taken under control by occupational hygienists.

Aspergillosis↗
PubMed1976

[Trypsin-inhibitory - capacity in humans to respirable allergens or irritants (author's transl)].

The trypsin-inhibitory-capacity was measured with a gelatine-film-technique after JAMES et al, in 520 persons suffering from complaints of upper and/or lower airways in connection with exposure to respirable allergens and/or irritants. As a control group 214 blood donors were examined. After determination of normal range, relations to age, sex, smoking habits, ventilatory parameters, bronchial reactivity, sedimentation rate of blood cells, alpha1-globuline and IgE were examined. In workers exposed to enzymes mean values to trypsin-inhibitory-capacity were found to be in normal range. Determination of trypsin-inhibitory-capacity is proposed to be used in examinations of workers who are to be exposed to enzymes.

Adult↗
PubMed1976

[Basic-diagnostic-criterions of respiratory insufficiency--results of a community work of the working group "pathophysiology of breathing" (author's transl)].

11 laboratories of the working group "Pathophysiology of Breathing" cooperated with standardized methods to obtain generally admitted practical criterions for the definition of respiratory insufficiency. Function parameters of 2800 examined persons in different diagnostic groups were tested by manual statistical analysis and computed by data processing system. which were assessed with regard to their usefulness as criterions for respiratory insufficiency. The arterial O2-partial pressure proved to be the most crucial criterion of respiratory insufficiency permitting objective evidence of a manifest respiratory insufficiency by hypoxeamia under standard efforts with a bicycle-ergometer. The screening parameters of ventilation such as vital capacity and forced exspiratory volume are suitable as subjective rapid methods for a quantitative estimation of one type of respiratory insufficiency: the ventilation disturbance. Investigations, which were carried out with a higher apparatus expense like the estimation of residual volume, the functional residual capacity, and the arterial CO2-partial pressure permit the further differentiation of causes of the respiratory insufficiency and the separation between respiratory partial- and global insufficiency. The parameters of gas exchange: O2-consumption, respiratory quotient, and the screening parameter of cardiocirculation heart rate are not or only limited useful as criterions of respiratory insufficiency alone.

Hemodynamics↗
PubMed1975

[The information content of bronchial reactivity tests (acetylcholinetest) for screening purposes].

It is described a methodology of the test of bronchial reactivity (acetyl choline test) in the area of occupational medicine. Experiments of retesting resulted in a good reproducibility without regard to the fact that the problems of aerosol dosage and retention are not exactly to be clarified at present. Concerning the information value of tests of bronchial reactivity their value in early diagnosis is emphasized compared with the spirometry without provocation. As essential factors of influence for the results of the tests proved to be the eventually existing diseases of the respiratory tract and the ventilatory initial values. Habits of smoking and age are of less influence.

Acetylcholine↗
PubMed1975

[Use of efficiency test as a standard method in occupational aptitude evaluation].

The judgment of the functional capacity of the body in the practice of occupational medicine is imperatively necessary for fitness examinations and controls. Issuing from the climbing apparatus method developed by Kaltenbach and Klepzig a simple screening test concerning the functional diagnosis is controlled as to its applicability in the practice of occupational medicine and its evidence with the help of ergometric comparative examinations. 266 healthy workers as well as 92 patients with chronic disease of the respiratory tract or ischaemic heart disease were examined. The results showed: -A good reproducibility of the measurement of the heart rate in the screening test of functional capacity, -a good correlation with submaximal loads on the bicycle ergometer and -a correspondence between the scaled results of the screening test and the loads of the bicycle ergometer from 53 to 71%, on an average 58%. For the whole group of persons examined the correlation coefficient r was 0.52.

Adult↗