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Biomedical subjects

E Rasmussen

Publications and source records attributed to E Rasmussen.

51 records · Page 3Linked to original sources

Tetracycline versus silver nitrate pleurodesis in spontaneous pneumothorax.

Silver nitrate pleurodesis as prevention against recurrence in primary spontaneous pneumothorax was started in our department on an empiric basis. In a controlled trial in 1981 the method was found to be as good as earlier stated, but the method has a high number of side effects and has never been widely accepted. In a prospective, controlled trial comparing silver nitrate pleurodesis with tetracycline pleurodesis, we found no differences in recurrence frequency, but the time of hospitalization was significantly longer in the silver nitrate group (p less than 0.05). Furthermore, we found a decrease of exudation and a decreased use of analgetics in the tetracycline group. As a consequence of the investigation, we have abandoned the silver nitrate method and now recommend tetracycline pleurodesis as the treatment of choice in primary spontaneous pneumothorax in patients with only tiny blebs on the surface of the lung.

Adolescent↗

Hiatus hernia. Report of three cases requiring immediate surgical intervention.

Three cases of hiatus hernias all necessitating emergency surgery are presented. The cases represent all three types, viz. sliding, paraoesophageal and combined hernias. It is stressed that hiatal hernias usually have a well-defined symptomatology, but sometimes do imitate symptoms from neighbouring organs or regions. In the event of acute obstruction immediate surgical intervention is mandatory, as in any other part of the gastrointestinal tract.

Acute Disease↗

Silver nitrate pleurodesis in spontaneous pneumothorax.

Pleurodesis provoked by instillation of silver nitrate as prevention against recurrence in primary spontaneous pneumothorax has been used for many years in the Department of Thoracic Surgery, Gentofte Hospital, University of Copenhagen. The treatment was originally instituted on a theoretical empiric basis. In a prospective, controlled investigation of pleurodesis versus simple drainage the empiric observations have been confirmed. With simple drainage we found ipsilateral recurrence of pneumothorax in 45%, while no recurrences in the pleurodesis group were found during an observation period of 5-19 months. The difference was statistically significant. The therapeutical gain using pleurodesis was 45% +/- 30%. Silver nitrate pleurodesis results in a longer hospitalization, raises the number of pleurocentesis because of increased pleural effusion and results in more pain than simple drainage. It is, however, our experience that the considerable therapeutical gain more than compensates for these negative effects. We recommend pleurodesis as the treatment of choice in primary spontaneous pneumothorax in patients with only tiny blebs on the surface of the lungs.

Adolescent↗

Acute Corynebacterium endocarditis causing aortic valve destruction. Successful treatment with antibiotics and valve replacement.

A case of acute infective endocarditis caused by diphtheroids in a healthy young male is described. The pathogenic role of the diphtheroids was verified by recognition of the same bacterium in 6 consecutive blood cultures and simultaneous rise of specific antibody titers. The infection was effectively controlled by antibiotic treatment, but destruction of the aortic valve led to progressive heart failure irresponsive to medical treatment. The affected valve was successfully replaced by a prosthetic valve, and the patient made a complete recovery. Neither congenital or acquired cardiac defects, nor signs of immunological deficiency could be detected.

Adult↗

Telehealth and communication technologies in health: summary and action plan.

INTRODUCTION: Rapid innovations and improvements in communication technologies have opened many new channels for health education and delivery, as well as disaster management. Theme 2 examined the role and applicability of these technologies to Disaster Medicine and Management and the various issues involved in their use. METHODS: Details of the methods used are provided in the introductory paper. The chairs moderated all presentations and produced a summary that was presented to an assembly of all of the delegates. The chairs then presided over a workshop that resulted in the generation of a set Action Plans that then were reported to the collective group of all delegates. RESULTS: Main points developed during the presentations and discussion included harnessing convergence, seeking interoperability, building partnerships and making it appropriate. This group identified four Principles of Action underlying its plan: (1) investigate possibilities, (2) identify stakeholders, (3) invite participation, and (4) involve discussants in activities. DISCUSSION: Action plans were categorized into three areas that included "thinking globally, acting regionally", forming a telehealth advisory group, and increasing corporate partnerships. CONCLUSIONS: Technology is opening many opportunities that have applications in disaster management. To optimize benefits, goals and standards must be agreed upon and implemented.

Cooperative Behavior↗