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Biomedical subjects

E Proca

Publications and source records attributed to E Proca.

98 records · Page 6Linked to original sources

[Anterior pelvectomy].

A total of 24 patients are presented, suffering with extensive vesical and genital cancers, in whom anterior pelvian exenteration was performed. The global mortality rate was of 16% and the postoperative evolution was very good in the remaining patients. It is considered that this type of intervention, provided that it is correctly performed, in association with an adequate ressuscitation, may have remarkably satisfactory results if we consider the advanced local stage of development of the tumors involved.

Adult↗

[Formolization of the bladder mucosa for hemostatic purposes].

The authors have used formalin solutions for the control of haematuria induced by bladder tumours. The 10 percent solution was efficient but induced severe side effects, such as peritonitis due to vesical necrosis, urethral fistulae, etc. The 1 percent solution is also efficient, and the local aggressivity is practically lacking, provided only 1--3 applications are carried out. The method should be used only in cases of haematuria that cannot be stopped by classical conservative means and in which surgery is not indicated, either temporarily or definitively.

Aged↗

The effects of endocrine therapy on plasma steroids in prostatic carcinoma patients.

Plasma testosterone (T), 5 alpha-dihydrotestosterone (DHT), T/DHT ratio, estrone (E1), estradiol (E2), E2/T ratio and 17-hydroxyprogesterone (17-OH-P) were measured in 70 patients with prostatic carcinoma (PCA) (T34, N01, M01), after endocrine therapy including: steroidal estrogens (polyestradiol phosphate = Estradurin monthly in injections of 80 mg; estradiol - 17 beta: 5 mg/d), nonsteroidal synthetic estrogens (DES: 5 mg/d; chlorotrianisene = TACE: 24 mg/d; DES-diphosphate = Honvan: 360 mg/d), orchidectomy and their combinations. All these forms of treatment lowered T, DHT, T/DHT ratio and 17-OH-P, the maximal suppression being observed after castration. No further decrease of the mentioned parameters was achieved by estrogen treatment of castrated patients, as compared with castration alone. In the noncastrated patients, steroidal estrogens were less effective than nonsteroidal ones, in terms of lowering T, DHT and T/DHT ratio. Significant decreases in estrone (p less than 0.05) and estradiol (p less than 0.01) levels were observed after nonsteroidal estrogen treatment and castration respectively, and extremely high values of circulating estrogens were found after steroidal estrogen administration.

17-alpha-Hydroxyprogesterone↗

[Transvesical prostatic adenomectomy without urethral catheter].

The results are presented, of trans-vesical prosthatic adenomectomy without urethral probe in 40 patients. The drainage of the bladder was achieved by vesical counter-incision, according to the technique suggested by Rose and Novak. A decrease by approximately 70% of the post-operative urinary infections, was obtained.

Humans↗

[Difficulties and errors in the treatment of cancer of the prostate].

On the basis of personal experience and of data in the specialized literature, the author supports the complex treatment of prostatic cancer, by radiation, surgery and hormones. Castration should be performed from the beginning. Neither should the advanced stages of the disease be abandoned because total prostato-vesiculo-cystectomy, followed by radiation therapy of pelvic lymph-nodes and hormone administration may still have encouraging results.

Aged↗