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Biomedical subjects

E Poon

Publications and source records attributed to E Poon.

23 records · Page 2Linked to original sources

Single papillary muscle and ostium primum defect.

Parachute mitral valve (single papillary muscle) is commonly associated with complete atrioventricular (AV) canal. We report a case of ostium primum defect associated with single papillary muscle.

Echocardiography, Doppler↗

Effect of magnesium sulfate on fetal heart rate variability in preeclamptic patients during labor.

Forty-two preeclamptic patients between 36 and 41 weeks gestation were investigated for baseline fetal heart rate (FHR) variability 1 hour after the initiation of magnesium therapy, at midlabor, and at the time of delivery. With a standard regimen of intravenous magnesium sulfate therapy, the mean maternal serum magnesium levels at the three different sampling times were statistically different (f = 6.94, p less than 0.01 by one-way analysis of variance), documenting the cumulative effect of continuous intravenous magnesium administration. The majority of the fetuses (86%) that exhibited a decrease in long-term FHR variability were associated with a maternal serum magnesium level above the lower limit of the therapeutic range (4.8 mg/dl). Of all fetuses whose maternal serum magnesium levels were 4.8 mg/dl or greater at delivery, only 40% exhibited a decrease in FHR variability. A higher mean maternal magnesium level, a higher mean cord blood magnesium level, and a higher total dose of magnesium sulfate were observed in the group of fetuses showing a decrease in FHR variability than in the group showing no change in FHR variability. The good fetal outcome seen in both study populations suggests that the effect of magnesium sulfate on FHR variability is a transient, reversible phenomenon that should not be considered as a sign of fetal distress.

Adult↗

Role of Chlamydia trachomatis in postpartum endometritis.

To investigate the role of Chlamydia trachomatis in puerperal endometritis, 72 patients with endometritis following vaginal or cesarean section delivery were studied. Blood, urine and endometrial cultures for aerobic and anaerobic bacteria and for C trachomatis were performed for all patients. C trachomatis was isolated in 25% of patients with endometritis. Patients with post-vaginal-delivery endometritis and a positive C trachomatis culture had a later onset of infection as well as a favorable clinical response to treatment despite persistence of C trachomatis in their endometrial cultures at the end of therapy. Cephalosporins failed to eradicate C trachomatis from endometrial cultures after five days of intravenous therapy.

Adult↗