Biomedical subjects
E Philip
Publications and source records attributed to E Philip.
Oral rehydration therapy in childhood diarrhoea: a comparative study.
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[15 000 full radiographs. Periapical, diseases resorptions, and impacted teeth in a study by the dental school in Stockholm].
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Pancreatitis in childhood.
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Postdiphtheretic paralysis (a study of 136 cases).
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Why infant mortality is low in Kerala.
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Early stimulation: C.D.C. Trivandrum model.
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Early intervention program (EIP)--the Indian experiences.
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Early intervention program for high risk babies--use of infant motor screen.
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[Salsolinol, an endogenous molecule. Possible implications in alcoholism, Parkinson's disease and pain].
Salsolinol can be formed either by condensation of dopamine with acetaldehyde, or by condensation of dopamine with pyruvic acid followed by decarboxylation. Salsolinol has a complex pharmacologic profile. Its opium-like activity may be related to alcohol dependency and to the effectiveness of naloxone during acute alcohol intoxication. Because they had noticed that alcoholism and Parkinson's disease rarely coexist, the authors undertook a study to confirm this fact and attempt to explain it by implicating salsolinol. Urinary excretion of salsolinol was found to increase following ingestion of alcohol, as well as in Parkinson patients under L-dopa treatment. The authors also found that urinary salsolinol was very low in untreated patients with Parkinson's disease. Salsolinol was detected in a number of foods and beverages. Separate assays of enantiomeres showed that the S enantiomere predominates in some foods whereas the R enantiomere is more abundant in humans. Lastly, the antinociceptive effects of salsolinol and its enantiomeres were studied in mice and antidepressant effects were evidenced using predictive tests.