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Biomedical subjects

E Petzold

Publications and source records attributed to E Petzold.

At least 19 recordsLinked to original sources
PubMed1989

[Anxiety, the heart patient and the organization of psychosomatic medicine].

Using a simplified biopsychosocial model, it is possible to outline several aspects of the partly real, partly unreal anxieties of the patient with heart disease, also in connection with defense strategies. Questions regarding the formal introduction of psychosomatic medicine are raised exemplary findings in the area of heart transplants, resuscitation and denial aspects are mentioned. The medical-care system and the patient complement each other in perception and strategic handling of anxiety, partly in stabilized, partly in destabilized ways. The development of a future organisation of psychosomatic medicine must differentiate between consultant services, liaison services, working groups and independent departments. As in the analytical-therapeutical situation, the understanding of the function of defense strategies is the prerequisite to overcome the symptom, which - experienced or not experienced, expressed or not expressed - means anxiety both for patient as well as for those who work in institutions.

Anxiety↗
PubMed1989

[Differentiation of the long-term effects of inpatient psychosomatic therapy of patients with anorexia nervosa].

In a catamnestic study of 103 anorexia nervosa patients treated at the university medical clinic in Heidelberg between 1970 and 1980, 51 patients were personally evaluated after 3, 6 years using a multi-dimensional system of criteria that covered 30 different symptom areas. There was a clear improvement with regard to constipation, vomiting, and the abuse of laxatives, various laboratory parameters, psychic symptoms, and vocational situation. Secondary amenorrhea, psychic suffering, and overly strong emotional ties to the family, however, were still found among two-thirds of the patients. Long-term success of treatment was found to correlate closely with an early age both for the onset of the disorder and for the beginning of treatment. Reduction of physical symptoms by the time of the post-examination was closely related to the extent of the family therapy carries out. In general, males appeared to benefit from treatment more than did female patients. Cluster analysis revealed that of four groups of patients studied, only one group could be called healthy; anorexia nervosa symptoms persisted to varying degrees in the other groups. Psychological testing using the PEF brought to light the following relationships: The greater the degree of illness at the time of the catamnestic study, the stronger the patient's tie to his/her own family, the greater the concern with physical appearance, the more achievement oriented, and the greater the aversion to playful activity.

Adaptation, Psychological↗
PubMed1985

[Clinical psychosomatics: blood pressure regulation. Problem status from the systems theory viewpoint].

The systemic aspect which integrates the family as a whole to the diagnostic and therapeutical process becomes more and more important in Clinical Psychosomatics. The development of a sound relationship between the hypertensive patient and his physician and the degree to which the patient is able to accept the drug treatment seem to be influenced not only by the personality structure of the individual patients but also by the interaction pattern of the whole family. The possible influence exerted by the special interaction patterns of the family on the chronification and/or replication of essential hypertension is shown by 1) the obvious negative non-verbal communication behaviour 2) the low intensity of verbal communication and 3) the high need of control, the setting of rigid bounds and a great inflexibility to solve the existing problems.

Adaptation, Psychological↗
PubMed1983

[Psychosomatic differentiation in patients following myocardial infarct].

An experimental study, based upon clinical impressions and theoretical considerations toward a differentiation of patients having suffered cardiac infarction, was employed to investigate the question of differentiation with regard to specific psychosomatic therapy. In conformity with other investigations it was observed that the patients with cardiac infarction could be classified into three groups. The theoretical considerations combined with the results from the experiments were the basis for the recommendation of specific therapeutic measures for each of the three groups: athletic group therapy for the more impulsive patients, single and group therapy for patients with regressive tendencies, combined group therapy in autogenetic training for sociable patients.

Adult↗
PubMed1980

The effect of brain fraction with fibroblast growth factor activity on regeneraton and differentiation of articular cartilage.

From bovine brains a fraction with fibroblast growth factor activity was prepared according to the method given by Gospodarowicz et al. (1978) and tested regarding to its biological effectiveness on articular cartilage regeneration in rabbits the cartilage in one knee-joint of those had been injured in a defined manner. The intraarticular administration of the brain fraction supported the healing process of the intrachondral lesions by conspicuously increasing the chondrocyte proliferation starting from preexisting cartilage tissue. In the case of subchondral lesions the neodifferentiation of chondrocytes out of the simple connective tissue that primarily filled the defect was promoted significantly.

Animals↗
PubMed1980

A bovine brain fraction with fibroblast growth factor activity inducing articular cartilage regeneration in vivo.

A bovine brain fraction with fibroblast growth factor (FGF) activity was prepared according to the method described by Gospodarowicz et al. and its influence on the healing process of experimentally produced intrachondral lesions in the knee-joint of rabbits was studied. Intraarticular administration of this preparation resulted in a substantial stimulation of the proliferation of "cluster cells", a special kind of chondrocytes which accumulate and form clusters.

Animals↗
PubMedDate not supplied

[Changes in the cartilage of the rat knee joint caused by running stress--a contribution to arthrosis research].

After running strain of Wistar-rats it is provable a small nonsignificant increase of the mean chondrocyte number per tissue area in the weight bearing cartilage of the medial femur condylus. Little foci of fibrillation and superficial localisated areas with loss of metachromasia are also visible in the cartilage. This tissue alterations appearing typical for a early phase of osteoarthrosis.

Animals↗
PubMedDate not supplied

[Side effects of nonsteroidal and steroidal anti-inflammatory drugs on cartilage metabolism--facts from research and practice].

On the base of experiments with laboratory animals and in the clinical practice existing results confirmed that steroidal and any non-steroidal antiphlogistic drugs have antianabolic and catabolic side effects on the connective tissue--and special articular cartilage metabolism. Biochemical and pharmacological investigations have shown that any of these drugs excert inhibitory effects on synthesis special of proteoglycans of ground substance in the cartilage. The use of such drugs in therapy of osteoarthrosis should be short-timed and limited to the treatment of patients with a so called activation of osteoarthrosis. For the long-term pharmacotherapy of osteoarthrosis should be used such antiphlogistic drugs without inhibitory side effects on the cartilage metabolism. The risk in occurrence of progressive articular cartilage damage in the therapy, special long-term therapy, with antiphlogistic drugs and the existence of pathological metabolic changes as a favourable factor for aseptic osteochondronecroses respectively as praearthrotic deformity is probably greater as in normal metabolic situations. The application of steroidal antiphlogistic drugs lead initial to good therapy results with reference to objective and subjective disease signs. These drug-therapy should be succombed an account of the severe negative side effects on cartilage metabolism (risk of osteochondronecrosis) a strict diagnosis and limited for the therapy of patients with rheumatoid arthritis (acute phase).

Adenosine Triphosphate↗