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Biomedical subjects

E Peters

Publications and source records attributed to E Peters.

At least 91 records · Page 5Linked to original sources
PubMed1986

A method of distinguishing between amalgam and graphite in tissue.

The clinical and histologic appearance of amalgam and graphite tattoos are similar; both appear as dark particles, although amalgam, after degradation, displays a characteristic binding to blood vessels, nerves, basement membrane, and fibers. Graphite particles also consistently exhibit a light yellow peripheral birefringence under strong polarized light. Amalgam particles may exhibit a similar birefringence, but often it is weak or absent. When histologic sections containing particles exhibiting birefringence are treated with 10% ammonium sulfide solution, graphite is unaltered, whereas the birefringence of amalgam particles, if present, is changed to orange, or the particles undergo dissolution.

Animals↗
PubMed1986

Oral angiolymphoid hyperplasia with eosinophilia.

Angiolymphoid hyperplasia with eosinophilia (ALHE) is an unusual and controversial lesion that occurs primarily in the head and neck area; oral involvement is rare. A case involving the labial mucosa, in which immunoglobulin deposits were found in association with a damaged centrally located artery, is described. The clinical and pathologic concepts presented in the literature are discussed. Suggestions that these lesions should be reclassified as epithelioid or histiocytoid hemangiomas may not apply to all of the cases that are acceptable as ALHE by current criteria. Different entities, which include vascular neoplasms, Kimura's disease, and possibly other reactive conditions, may be encompassed in the Western literature as ALHE. Involvement of a small artery and occasionally a vein, often with evidence of vascular damage, was reported in 24% of the cases of ALHE that were reviewed. Single nonrecurrent lesions were seldom found in association with blood eosinophilia, although in the absence of eosinophilia, single and multiple or current lesions occurred in 60% and 40% of the cases, respectively.

Adult↗
PubMed1986

[Computerized tomographic study of medieval coffins].

Two medieval coffins containing neonates were examined by CT. The advantages of using computed tomography, compared with conventional x-ray techniques, for analysing various objects within a receptacle are demonstrated.

Burial↗
PubMed1986

Botryomycosis of the oral regions.

Botryomycosis is an unusual bacterial infection capable of producing chronic granulomatous inflammation and characterised by the production of distinctive grains formed by the interaction of the infective bacteria with the host tissues. The occurrence of this infection in a healthy individual generally results in locally destructive lesions which can clinically mimic a sarcoma. A case is reported involving the oral regions of a healthy adult male which illustrated these features and a discussion is presented of the diagnostic features of this condition.

Adult↗
PubMed1986

Granular cell reaction to surgical glove powder.

The histopathologic features characteristic of the inflammatory response associated with starch powder used as a lubricant for surgical gloves were investigated by implanting starch granules into 3 separate sites on the right side of 8 male Wistar rats. On the opposite side, a sham-operated site and sites implanted with talc were used as controls. Two rats were killed at 1, 2, 3 & 4-week intervals and tissue from the implanted sites was assessed for distinctive features. It was found that a consistent feature of the starch-implanted sites was the presence of large histiocytes containing prominent PAS-positive, diastase-resistant inclusions. These cells were not found in the control sites and, thus, were considered characteristic of starch contamination in tissue, even in the absence of identifiable starch granules. A possible clinical case of reaction to starch, identified retrospectively, using these results is discussed.

Animals↗
PubMed1985

Starch artifacts in oral cytologic specimens.

Starch powder from surgical gloves is a common artifact that may superficially resemble atypical epithelial cells or spores in oral cytologic specimens. This article describes the distinguishing features of starch granules visible under a light microscope and discusses their clinical relevance.

Cheek↗
PubMed1983

Dexamethasone, prostaglandin A, and retinoic acid modulation of murine and human melanoma cells grown in soft agar.

The cloning efficiencies of a murine melanoma cell line (S91 CCL 53.1) and a human melanoma cell strain (C8146c) were inhibited by dexamethasone (DEX), prostaglandin A1 (PGA1), and beta-all-trans-retinoic acid (RA) in a dose-dependent manner. Murine melanoma tumor colony-forming units (MTCFU) were inhibited more than 99% by DEX (1 X 10(-7) M) and RA (1 X 10(-7) M) with a concentration needed to produce a 50% reduction in colony formation for both hormones of 5 X 10(-9) M. Combinations of DEX and RA effected a synergistic inhibition on colony formation, which was reflected by a 11/2 log reduction in the hormone concentration needed to produce a greater than 99% inhibition of colony formation. When PGA1 was added to DEX and RA, a greater than additive reduction in colony formation was observed. Human MTCFU from cell strain C8146c were inhibited more than 85% at an RA concentration of 1 X 10(-7) M, but they were reduced only to 40% of control at a DEX concentration of 1 X 10(-6) M. DEX-RA produced an additive inhibition of colony formation. Addition of submaximal amounts of PGA1 to DEX-RA combinations or to either hormone alone resulted in synergistic reduction of human MTCFU. These results demonstrated that the proliferative potential of human and murine melanomas can be simultaneously regulated by DEX, PGA1, and RA.

Agar↗
PubMed1981

Ia-bearing macrophages in athymic mice: antigen presentation and regulation.

Ia-bearing macrophages from spleens and peritoneal cavities of athymic (nu/nu) and euthymic (nu/+) were compared. Macrophages from both strains of mice had equal antigen-presenting ability. The basal numbers of unstimulated Ia-bearing peritoneal macrophages were equal, but only euthymic mice recruited large numbers of Ia-bearing macrophages after Listeria infection. The i.p. injections of a "macrophage Ia-recruiting factor" induced exudates rich in Ia-bearing macrophages in both athymic and euthymic mice. These data suggest 2 levels of control of Ia-bearing macrophages: a basal T cell-independent level and a stimulated level dependent on mature T cells.

Animals↗