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Biomedical subjects

E Perlick

Publications and source records attributed to E Perlick.

At least 19 recordsLinked to original sources

[The value of computed tomography in monitoring the preoperative chemotherapy of osteosarcoma].

Computed tomography was performed in 45 patients with osteosarcomas before and after preoperative chemotherapy. Changes of bone alterations, intramedullary tumour spread and the size of soft tissue masses are computer tomographic criteria for tumour response after chemotherapy. The computed tomography decision of responder or non-responder was correct in 37/45 patients. In comparison with conventional x-rays CT was superior. CT is a reliable method for preoperative extension diagnosis and for the decision-marking for limb-saving operations.

Adolescent↗

[The value of computed tomography for the pretherapeutic staging of esophageal cancer].

CT examination was performed in 50 patients with histologically proved carcinoma of the esophagus. In 21 patients the CT findings were compared with the surgical or autopsy specimens. CT is revealed as a valuable diagnostic method for the estimation of infiltrating tumors. Limitations were seen in the precise judgement of the infiltration into the different layers of the adjacent organs and in the recognition of regional lymph node metastases. Nevertheless CT is recommended as a valuable staging procedure in carcinoma of the esophagus.

Carcinoma, Squamous Cell↗

[Malignant fibrous histiocytoma of soft tissue. Possibilities and limitations of computed tomography].

Computed tomography was performed in 27 patients with confirmed malignant fibrous histiocytoma of the soft tissue. Compared with the CT results obtained in other tumours of the soft tissues. CT accuracy in malignant fibrous histiocytoma was only 74%. Non-typical attenuation values, diffuse tumour growth and non-typical contrast enhancement are discussed as reasons for the diagnostic understaging or overstaging of these soft tissue tumours. A higher accuracy was found on ultrasound examination with regard to tumour extension. Bone destruction was better visualised by CT. A base-line CT is recommended postoperatively for the earlier detection of recurrent tumours in further investigations.

Adult↗

[Confirmation power of computer tomography for suspected mediastinal tumors].

CT investigations of the mediastinum were compared in their diagnostic power with conventional X-ray pictures. With striking mediastinal broadening, CT always allowed to identify the origin of the tumour, its exact location and relationship with neighbouring organs and vessels. Determining its expansion proved valuable for the further therapeutic procedure. Density measurements gave indications as to the type of tumour. Fine-needle puncture permitted to narrow differential diagnostic findings. Finally, CT was used especially with systemic diseases for the search of lymph nodes in case of known tumours such as bronchial and mammary cancer. Also, pathological vascular processes, such as aneurysms, could be well visualized. This allowed to restrict the more stressing investigations, e.g. mediastinoscopy and angiography.

Adolescent↗