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Biomedical subjects

E Peli

Publications and source records attributed to E Peli.

11 recordsLinked to original sources

Limitations of image enhancement for the visually impaired.

Image enhancement as an aid for the visually impaired may improve visibility of TV programs and provide portable visual aid. This paper describes the current techniques for image enhancement and their underlying models. The limitations of the various techniques and of potential methods of implementation are high-lighted. Initial work in this area was based on a linear model. The finite dynamic range available in the video display and contamination of the enhanced image by high spatial frequency noise limited the model's usefulness. I propose a method to address some limitations of the original model that considers the nonlinear response of the visual system and requires enhancement of subthreshold spatial information only. This modification may increase the dynamic range available by decreasing the range previously used by the linear models to enhance visible details. However, for the modified technique to be most effective, the enhancement has to be continuously tuned, based on the patient's visual loss and the spatial frequency content of the displayed images. The implications of these limitations for the potential implementation in TV are discussed. Implementation of an image-enhancing visual aid in a head-mounted, binocular, full-field, virtual vision device may cause substantial difficulties. Patient adaptation may be difficult due to head movement and interaction of the vestibular system response with the head-mounted display. An alternate, bioptic design is proposed in which the display is positioned above or below the line of sight to be examined intermittently, possibly in a freeze-frame mode. Such implementation is also likely to be less expensive, enabling more users access to the device.

Audiovisual Aids

Differences in tests of aniseikonia.

The New Aniseikonia Test (NAT), a hand-held direct-comparison test using red/green anaglyphs, has several potential advantages as a screener. We compared the validity of the NAT to that of the Space Eikonometer in three experiments: (1) aniseikonia was induced by calibrated size lenses in a double-blind study of 15 normal subjects; (2) habitual aniseikonia was measured with both instruments in four patients; and (3) eight of the normal subjects were retested with a computer-video simulation of the NAT. The NAT underestimated induced aniseikonia by a factor of 3 in the normal subjects and underestimated habitual aniseikonia in four patients. The Space Eikonometer correctly measured the magnitude of induced aniseikonia in the normal subjects. The simulation test did not show underestimation in the eight normal subjects. We could not attribute the NAT's underestimation of aniseikonia to the red/green anaglyph method, printing error, psychophysical method, or the direct-comparison test format. We speculate that the NAT induces a different sensory fusion response to aniseikonia than do the other tests, and that this altered sensory fusion response diminishes measured aniseikonia. We conclude that the NAT is not a valid measure of aniseikonia.

Adult

Image analysis of changes in drusen area.

Computerized image processing was used to analyze color fundus photographs of 11 patients (22 eyes) with macular drusen who were followed for more than 2 years (mean follow-up, 4.7 years). Significant changes over time (more than +/- 20% of baseline area) were measured in the surface area of macular drusen in 18 of 22 (82%) eyes. An increase in the drusen area was associated significantly with eyes with mostly hard drusen and an initially smaller drusen area; but a decrease was associated with eyes with mostly soft drusen and an initially larger drusen area (P less than 0.01). The mean absolute rate of change in the drusen area was more than twice as great in eyes with mostly soft drusen compared with those with mostly hard drusen (P less than 0.05). All eye pairs studied showed a concomitant increase or decrease in the drusen area.

Aged

Multiresolution, error-convergence halftone algorithm.

A new halftone algorithm is described. The algorithm is designed for implementation on a parallel architecture in order to provide fast, progressive coding of moderate-resolution images. The design is based on a multiresolution, hierarchical, pyramidal structure. At each pyramid level, the binarized image is compared with the original, gray-tone image over a successively larger window of pixels for calculation of a weighted averaged error. Within each level, selected binarized pixels are tested for possible changes in the binary assignment. The binary assignment is changed if the change results in a lower average error over the entire window. Varying the selection of test pixels can cause the same process to provide clustered-dot patterns and dithering. A comparison of performance with the best implementation of the error-propagation algorithm is presented visually. Quality is compared also in terms of isotropy of the texture and the appropriate blue-noise characteristics in areas of uniform gray tone. The benefits of this algorithm are realized with moderate-resolution display of the order of 512 dots X 512 dots. The processing can be carried out on smaller blocks since the results can be combined without any visible seams or edge effects.

Algorithms

Effect of luminance on suprathreshold contrast perception.

Perceived contrast was measured under natural viewing conditions with the use of contrast-matching and magnitude-estimation paradigms and found to be independent of luminance over a range of luminances from 37.5 down to 8 cd/m2. However, this contrast constancy broke down when the dimmer target was below 8 cd/m2. The perceived contrast of the dimmer target then fell below that expected from contrast constancy. The extended range of contrast constancy previously reported [J. Physiol. 252, 627 (1975); Vision Res. 16, 1419 (1976)] has been thought to imply neural mechanisms with unlimited constancy, but these researchers permitted differential adaptation to the brighter and dimmer targets, which were seen haploscopically (by different eyes). As our natural-viewing procedure ensured that both bright and dim targets were presented to retinal areas in a roughly constant state of adaptation, our failure to find extended contrast constancy implies an important limitation on the neural processing of contrast.

Adaptation, Ocular

Image invariance with changes in size: the role of peripheral contrast thresholds.

The appearance of objects generally does not change with changes in the size of their retinal image that occur as the distance from the observer increases or decreases. Contrast constancy ensures this invariance for suprathreshold image features, but fully robust size invariance also requires invariance at threshold, so that near-threshold image features do not appear or disappear with distance changes. Since the angular size and the eccentricity of image features covary with distance changes, the threshold requirement for invariance could be satisfied approximately if contrast thresholds were to vary as the product of the spatial frequency and the eccentricity from the fovea. This model fits contrast thresholds for orientation identification over spatial frequencies of 1-16 cycles/deg and for retinal eccentricities of as much as 23 deg. Contrast detection thresholds from six different studies conform to this model over an even wider range of spatial frequencies and retinal eccentricities. The fitting variable, the fundamental eccentricity constant, was similar for all three studies that measured detection along the horizontal meridian and was higher for the orientation identification contrast thresholds along the same meridian. The eccentricity constant from studies that measured detection along the vertical meridian was higher than the constant calculated for the horizontal meridian and lower than the eccentricity constant for chromatic isoluminance gratings. Our model and these results provide new tools for analyzing the visibility of displays and for designing equal-visibility or variable-visibility displays.

Contrast Sensitivity

Image enhancement for the visually impaired. Simulations and experimental results.

Digital image enhancement has been proposed as an aid for the visually impaired. The capability of two enhancement techniques to improve recognition of images by patients with central scotoma or cataracts was evaluated using image-processing simulations and direct patient testing. Enhancements and simulations were based on measurements of contrast sensitivity loss for patients with macular disease. Contrast sensitivity loss was measured using Gabor-type localized stimuli and paradigms that are appropriate for analyzing form perception. The simulations using the contrast sensitivity data suggested that patients with moderate visual loss (20/70-20/200) may have difficulty recognizing faces and may benefit from enhancement by both of the techniques used. Ability to recognize celebrities from enhanced images improved for 39 of the 46 patients tested. The improvement was significant (P less than 0.05) for 16 of the 38 patients with central visual loss and for 3 of 8 patients with anterior segment media opacities tested. The simulations suggest that the benefits of image enhancement may be similar or even greater for recognition of other types of images.

Adult

Contrast in complex images.

The physical contrast of simple images such as sinusoidal gratings or a single patch of light on a uniform background is well defined and agrees with the perceived contrast, but this is not so for complex images. Most definitions assign a single contrast value to the whole image, but perceived contrast may vary greatly across the image. Human contrast sensitivity is a function of spatial frequency; therefore the spatial frequency content of an image should be considered in the definition of contrast. In this paper a definition of local band-limited contrast in images is proposed that assigns a contrast value to every point in the image as a function of the spatial frequency band. For each frequency band, the contrast is defined as the ratio of the bandpass-filtered image at the frequency to the low-pass image filtered to an octave below the same frequency (local luminance mean). This definition raises important implications regarding the perception of contrast in complex images and is helpful in understanding the effects of image-processing algorithms on the perceived contrast. A pyramidal image-contrast structure based on this definition is useful in simulating nonlinear, threshold characteristics of spatial vision in both normal observers and the visually impaired.

Contrast Sensitivity

Study of eccentric fixation with secondary visual feedback.

Secondary visual feedback (2VFB) is a visual signal derived from continuous measurement of eye position and provides an extra artificial indication of the point of gaze. 2VFB may be eccentrically displaced and subjects are able to visually superimpose 2VFB onto a visual target signal and thus achieve and maintain eccentric fixation. Initial transient patterns of movement depend upon training but even naive subjects can achieve eccentric fixation within the first 40 s of such a task. Individual strategies and idiosyncratic patterns are exaggerations of normal control and fixational eye movements. The variance of maintained fixation increases with eccentricity and appears to be related to visual acuity as well as to precision of ocular motor control.

Biofeedback, Psychology

Latency of peripheral saccades.

Displaying the point of gaze to the observer in addition to a point target provides a secondary visual feedback (2VFB). Eccentric fixation is achieved using a biased 2VFB to yield an experimentally imposed "eccentric fovea." The target is suddenly moved to a new position and the task is to regain it, in the "eccentric fovea". It is found that the pattern of eye-movement response consistently starts with saccadric foveal exploration of the target, but its latency has twice the duration of a regular voluntary saccade. Practice, however, makes for the shortened latency tending asymptotically to the regular saccadic duration.

Eye Movements

Pursuit eye movements in late-onset esotropia.

Horizontal, smooth pursuit eye movements were recorded from adults and children with infantile and late-onset esotropia using a remote, video-based, eye-movement recording system. Each subject monocularly tracked a 0.5-degree target moving back and forth on a video monitor at a constant velocity of 10 degrees, over a range of 12 degrees. Each subject's nasal and temporal gain (eye velocity/target velocity) was measured. Confirming the results of previous studies, we found that infantile esotropes had asymmetrical pursuit eye movements (nasal gain greater than temporal gain) while late-onset esotropes had symmetrical gains. However, unlike previous investigators, we found that half of the late-onset esotropes had impaired pursuit gain. The magnitude of the pursuit abnormality and the amount of refractive error were correlated--patients with the highest refractive error had the lowest pursuit gain.

Adult