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Biomedical subjects

E Pearse

Publications and source records attributed to E Pearse.

8 recordsLinked to original sources
PubMed1986

Fine needle aspiration cytology and exfoliative biliary cytology in the diagnosis of hilar cholangiocarcinoma.

Nineteen patients with suspected malignant obstruction at the confluence of the bile ducts had exfoliative biliary cytology and fine needle aspiration cytology performed. Of these patients 14 cases were histologically proven to be cholangiocarcinoma, and 3 others followed a clinical course which was clearly malignant. Fine needle aspiration cytology gave a true positive result in 14 patients (87.5%), whereas exfoliative cytology was positive in 11 (73%). There were no false positive results and no complications from either procedure. Both the cytological procedures are rapid and safe and are useful for preoperative planning of surgical and intraoperative diagnosis.

Adenoma, Bile Duct↗
PubMed1984

Malignant melanoma of the sympathetic chain: with a consideration of pigmented nerve sheath tumours.

A case of malignant melanoma of the posterior mediastinum, arising from the sympathetic chain is reported. The structural features and the presence of long-spaced collagen on electron microscopic examination suggest schwannian derivation of the tumour. Similar tumours are reviewed and the histogenesis of pigmented nerve sheath tumours in general is discussed. The term 'malignant melanotic schwannoma' is probably the most appropriate for the tumour entity described here.

Adult↗
PubMed1983

Combined bipedal lymphangiography, CT scanning and transabdominal lymph node aspiration cytology for node staging in carcinoma of the prostate.

Forty-two patients with carcinoma of the prostate have been studied by bipedal lymphangiography, abdominal CT scanning and percutaneous transabdominal lymph node aspiration cytology to try to increase the accuracy of lymph node staging. The use of two independent radiologists to report the lymphangiograms did not improve the accuracy of reporting. CT scanning was of value only in patients in whom the lymph nodes were not opacified on lymphangiography. Aspiration cytology was positive in 8 of the 40 patients who were studied. There was no morbidity. Six of these 8 patients had MO disease, three had TO tumours and were not on treatment. A poor correlation was found between the presence of lymph node metastases and the Gleason score. Percutaneous transabdominal lymph node aspiration cytology is a safe procedure. When positive, it avoids the need for a staging lymphadenectomy and so helps to identify those patients for whom local treatment is not applicable.

Biopsy, Needle↗