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Biomedical subjects

E Papiernik

Publications and source records attributed to E Papiernik.

At least 127 records · Page 7Linked to original sources

[A study of fetal pulmonary maturity using amniotic fluid obtained from the vagina after premature rupture of membranes].

Amniotic fluid was obtained from the vagina not more than 24 hours before delivery in 100 patients who had premature rupture of the membranes. Thirty per cent of these cases had contamination with blood or with meconium. Phosphatidylglycerol (PG) estimate the degree of lung maturity using an immunological method (AMNIOSTAT-FLM test). In the 22 cases where the gestational age was 35 weeks or less there were two cases of hyaline membrane disease. In 68% of the 22 cases, the PG was negative, intermediate in 14% and positive in 18%. One of the cases of hyaline membrane disease was accompanied by fluid that was not infected and that was negative for PG; the other case had infection with S. faecalis and the PG was intermediate. On the other hand in the 78 cases when the pregnancies had lasted longer than 35 weeks there were no children who had hyaline membrane disease. The PG reaction was positive in only 57% of these cases. Search for bacteria showed infection in 10 cases (three with alpha-haemolytic streptococci, four with group B beta-haemolytic streptococci and three with E. coli). Determination of PG on the supernatant of reference strain cultures showed positive results for S. faecalis and E. coli. In conclusion, the poor specificity of the test (48%) and the possibility that when there was bacterial contamination false positive results were obtained shows that looking for fetal maturity by testing amniotic fluid from the vagina is unreliable and is contra-indicated.

Amniotic Fluid↗

[Antenatal diagnosis and ethical problems].

The fast development of techniques detecting diseases or malformations of the fetus during the 2nd third of pregnancy has led to a real evolution in our knowledge. We can recognize minor or major abnormalities, as well as many hereditary or acquired diseases. This revolution raises considerable ethical problems because, at the same time, our ability to receive and operate the children with malformations as early as birth is ever improving. And yet the mothers often ask for induced abortion. What are we supposed to do? What are the acceptable limits?

Abortion, Therapeutic↗

[Utero-ovarian mucoid carcinoma, of presumed wolffian duct origin (pure mesonephrotic carcinoma). Apropos of a case and review of the literature].

This is a case report of a rare tumour of the ovary originally developing from the embryonal vestiges of the Wolffian duct and becoming a pure mesonephrotic carcinoma. Although initially considered to be benign, the course of the tumour is one of a potential low grade long term malignancy. Histological changes are of a pure mesonephrotic carcinoma or of a female adnexal tumour probably of wolffian origin (FATWO). It showed few specific traits. Each site of the development is constantly linked to the anatomy of the Wolffian duct. Metastases and recurrencies can develop late (after 5 to 10 years) following radical surgery. A survey of the literature confirmed the salient features of these tumours, which can differ from those of Müllerian origin.

Adenocarcinoma, Mucinous↗

[Sports and pregnancy. A review of the literature].

A review of the literature concerning sport during pregnancy is presented. The mother's heart rate, arterial blood pressure, systolic ejection fraction and cardiac output undergo the same changes during exercise in the pregnant and non-pregnant patient. The increase in the fetal heart rate during maternal physical exercise does not adversely affect the fetal outcome. The uterine blood flow is diminished during exercise. The respiratory rate increases equally in pregnant and non-pregnant women. The maternal response to effort is also modified by weight gain during pregnancy, by changes in the musculo-skeletal system, and by maternal temperature control during exercise. Weight gain, uterine contractility, duration of pregnancy, labour and neo-natal conditions are not altered by sport during pregnancy. Contra-indications to sport during pregnancy include threatened premature labour, and conditions associated with an increased risk of prematurity. A previous history of fetal growth retardation, acute fetal distress, or the presence of diabetes or arterial hypertension is a contra-indication to sport during pregnancy. The advice which should be given to a pregnant woman wishing to continue her sporting activities during pregnancy is outlined.

Female↗

[Peritonitis and cerclage of the cervix uteri].

Authors report a case of peritonitis following uterine cervical cerclage in a patient with twins. This observation leads to two problems: complications of cerclage and its real indications. Two recent controlled studies conclude that in a singleton pregnancy, there is no advantage in cervical cerclage in prolonging the gestation period and in decreasing the perinatal mortality. However, the last MRC/RCOG study, still in progress, shows that in a preliminary study, there is a small advantage in cervical cerclage in high-risk-pregnancy with two previous mid trimester spontaneous abortions and/or with premature labor. In multiple pregnancies especially in twin pregnancy, the problem remains unsolved.

Adult↗

[The Zavanelli maneuver: use during breech retention of the head in the birth canal. Apropos of a case].

A case is presented where Zavanelli's manoeuvre was carried out when the chin of the fetus was caught up above the symphysis pubis. This new concept for managing partially born infants that cannot be delivered vaginally, by Cesarean section improves greatly the prospect for survival of the fetus with minimal extra risk for the mother. It is easier to carry out the manoeuvre when the patient is under epidural analgesia.

Adult↗

Evaluation of the benefit of setting up a decentralised obstetric-surgical structure in order to reduce maternal mortality and transfers in the Ivory Coast.

Our purpose is to study the way to reduce maternal mortality when introducing a structured obstetric and surgical center to a community previously without such a center. The study was done in Ivory Coast, where such a structure was set up in 1982 in a rural hospital at Divo. It has been observed that with such a structure there are no more transfers of women from Divo to the teaching hospital at Cocody, and a reduction in maternal mortality at Divo. This observation regarding the value of bringing obstetric services to communities currently without them could be a way among those available to reduce maternal mortality in a developing country such as the Ivory Coast.

Cote d'Ivoire↗

Chorionic villus sampling (CVS). Randomized study of efficacy of two transcervical biopsy methods: aspiration canulas and small forceps.

A randomized study of two transcervical biopsy methods was performed. One method involved the use of an aspiration catheter and the other a tissue biopsy forceps. 120 chorionic villus samplings were performed in 30 patients. The percentage of success in taking biopsies and the resulting number of karyotypes were identical in both groups. The amount of removed trophoblastic tissue was greater when the forceps was employed. When the aspiration catheter was used, a sufficient amount of trophoblastic tissue was obtained for karyotyping purposes. It was easier to insert the aspiration catheter than the forceps. The echogenicity of the catheter and forceps were identical. The aspiration catheter has two advantages. Firstly, it is malleable and fits to the anatomy of the cervical canal and the site from which the biopsy is to be taken. Secondly, it is disposable.

Adolescent↗

Intra-uterine device failure: relation with drug use.

A case-control study was undertaken in order to test the relationship between commonly used anti-inflammatory agents and the efficacy of intra-uterine devices (IUDs). Women who had become pregnant while wearing an IUD were compared with non-pregnant IUD users. 717 cases and 717 controls were recruited from the same medical practices. The case-women (IUD failure) used anti-inflammatory drugs, particularly aspirin, more frequently than the controls (p less than 0.001). In contrast, oral progestins, taken in the second part of the cycle (16th to 25th day) were more frequently used by the control-women group (p less than 0.001). Although cases and controls differed in age and gravidity (younger and higher, respectively) standardization for these items did not change the findings for drug use.

Age Factors↗

Chorionic villus sampling after first trimester diagnosis of fetal cystic hygroma colli.

Diagnostic findings of four cases of cystic hygroma discovered at 11 weeks of gestation are reported. The discovery of cystic hygroma by echotomography was followed by sample taking of chorionic villi which revealed one case of monosomy X and three cases of trisomy 18. Caryotype determination in the presence of cystic hydroma is essential for diagnostic confirmation and subsequent genetic counselling.

Adult↗

Decentralization of maternity care.

One of the main reasons for the high maternal mortality rates in developing countries is the need to transfer patients long distances to city hospitals when they develop complications. Local obstetric facilities would relieve this situation.

Cote d'Ivoire↗