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Biomedical subjects

E Papiernik

Publications and source records attributed to E Papiernik.

At least 235 records · Page 13Linked to original sources

Hypothesis of an ovular regulation of pregnancy weight-gain.

A retrospective study of 127 twin pregnancies has been carried out, considering the relation between maternal weight-gain and zygosity of the ovum. At 28 weeks of gestation, the maternal weight-gain distribution goes on according to a bimodal curve, the analysis of which shows that each pike corresponds to one twin-pregnancy variety. Whatever the considered term might be (28-32-36 weeks), the maternal weight-gain is higher in DZ than in MZ pregnancies, and it should be pointed out that toxemic pregnancies, in each group, have nothing to do with this difference. This maternal weight-gain difference may reflect the known quality difference between MZ and DZ ova. The data lead to set up the more general hypothesis of an ovular regulation factor of the maternal weight-gain, in addition to classic data such as the own fetal weight, its annexes, and maternal diet.

Body Weight↗

Suspected postpartum endometritis: a controlled clinical trial of single-agent antibiotic therapy with Amox-CA (Augmentin) vs. ampicillin-metronidazole +/- aminoglycoside.

Endometritis is the commonest postpartum complication and is one of the leading causes of maternal morbidity, if not mortality. The object of the present clinical trial was to assess the efficiency of single-agent therapy with Amox-CA (Augmentin) (formulation which includes a beta-lactamase inhibitor), against standard treatment which necessarily combines two or three antibiotics depending on the clinical severity of the case. 101 patients were evaluated in this comparative prospective randomized study. The mild forms were defined by a temperature between 37.9 and 38.4 degrees C and the severe forms by a temperature of more than 38.5 degrees C (which alone required treatment with three antibiotics). The time until the return of apyrexia and the clinical cure rate, as well as duration of treatment, were identical in both groups. Tolerance was good: no side effect requiring discontinuation of treatment occurred. In the population value, the use of a single-agent therapy with amoxycillin/clavulanic acid is not significantly different from a double or triple-agent regimen, and the convenience is increase.

Adult↗

Gender differences in neonatal subcutaneous fat store in late gestation in relation to maternal weight gain.

OBJECTIVE: To study gender differences in fat store in human newborns and their relation to duration of gestation and maternal weight gain. METHODS: The ratios subscapular skinfold thickness/body weight (SST/BW) and tricipital skinfold thickness/body weight (TST/BW) were calculated in a sample of 13609 premature and term neonates from the maternity hospital of Clamart, Hauts-de-Seine, France. RESULTS: Whereas BW, SST and TST increased with gestational age, SST/BW and TST/BW ratios decreased regularly, in males as in females. This result reflects a progressive reduction of subcutaneous fat store per body weight unit as the duration of gestation increases. Males had smaller values of SST/BW and TST/BW ratios than females whatever the gestational age. Increasing maternal weight gain during the third gestational trimester did not improve the subcutaneous fatness per body weight unit of the newborn. Earlier amount of maternal weight gain had an effect on the TST/BW index exclusively in females. CONCLUSIONS: In newborns, a gender difference was observed in the ratio of subcutaneous fat per unit of body weight; this ratio is lower in males than in females. This result argues for a gender difference in mobilization of fat store to ensure normal growth in the last weeks of pregnancy: males lose more fat but gain more weight than females in this period. Late maternal weight gain does not affect the proportion of subcutaneous fatness by body weight unit in both genders.

Adult↗

Ethnic difference in duration of pregnancy.

It is suggested that the observed difference in duration of pregnancy between Blacks and Whites is partly physiological since it is not entirely explained by social inequities alone. This study compares women with well-defined gestational periods seeking attention at the Antoine Béclère Maternity Clinic. Group A consists of French women of European ancestry, Group B, those born in the French Antilles of mixed ancestry, and Group C black African women with insignificant European admixture. When compared to Group A, within each socio-economic class, group B and C have shorter gestational periods. These differences persist after adjustment for socio-economic variables, so that other explanations should be considered, specifically genetic determinants.

Africa↗

Lipid composition of plasma obtained from various parts of the vascular system of the rabbit.

Lipid concentrations were compared in the arterial blood, peripheral venous blood (pinna), and blood from the portal vein, hepatic vein, inferior caval vine and both renal veins (right and left). Greatest differences were found between the arterial blood and venous blood from a peripheral vein and hepatic vein. For assessment of the degree of lipid assimilation by the peripheral tissues simultaneous determination of triglycerides and non-esterified fatty acid concentrations in arterial blood and peripheral venous blood was found to be most useful. Liver ability of lipid synthesis can be measured on the basis of difference in the concentrations of cholesterol, non-esterified fatty acids and phospholipids in the arterial and venous blood leaving the liver. Blood passage through the kidneys had no influence on changes in the lipid concentration.

Animals↗

[Contraception and subsequent fertility. General review on the reversibility of oral contraception].

We have carried out a general review of the problem of reversing the contraceptive mehtods using oestrogen-pregestogen contraceptives. We have very carefully reviewed the onset of long cycles showing clearly that they occur more easily in women who have started with irregular cycles, as do post-pill amenorrhoea cases. Spontaneous abortions seem to occur just as often after the pill as in the general population and the alarm that was raised by D. Carr seems to us to be very exaggerated. The infants are normal, have a lower perinatal mortality when we take into account the patients who use this method and there are no more congenital abnormalities than in other patients.

Abnormalities, Drug-Induced↗