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Biomedical subjects

E P Mukhin

Publications and source records attributed to E P Mukhin.

At least 19 recordsLinked to original sources
PubMed1992

[The importance of thoracostomy in treating pleural empyema with bronchial fistulae in patients with pulmonary tuberculosis].

In contrast to the nonspecific pleural empyemas, which are managed effectively by closed methods of débridement, management of patients with tuberculous pleural empyema and bronchial fistulas requires early application of thoracostoma, which allows cavity débridement, long-term antituberculous chemotherapy and preparation to radical surgery. This was confirmed by the comparative analysis of the results of radical operations after closed and open methods of management of empyema cavity in 139 patients. The site of thoracostoma application is determined by the location and size of an abscess and the forthcoming radical operation. Long-action bandages with chlorhexidine bigluconate and ultraviolet radiation are prescribed for the débridement of open pleural empyemas.

Bandages↗
PubMed1992

[Effectiveness of hyperbaric oxygenation in the treatment of postresection bronchial fistulas].

The article discusses the results of treatment of 84 patients with postresection tuberculous pyothorax and bronchial fistulas with hyperbaric oxygenation session (HBO) included in the complex of therapeutic measures. As a result, the bronchial fistulas closed in 30 (35.7%) patients, the diameter of the fistulas reduced markedly in 20 (24.3%) patients, the bronchial fistulas failed to close in 40% of cases. As the result of HBO therapy the count of red cells and lymphocytes increased, leukocytosis and eosinophilia reduced, the ESR diminished. The content of ALT transaminase, sugar, total protein and bilirubin decreased. The migration index for all immune antigens in the reaction of leukocyte migration inhibition and in the nitro blue tetrazolium test increased. HBO promoted the efficacy of radical operations by 29.4% as compared to that in the control group of the similar patients.

Bronchial Fistula↗
PubMed1989

[The use of hyperbaric oxygenation in the combined treatment of postresection tuberculous pleural empyema with bronchial fistulae].

The results of treating 67 patients with postresection tuberculous empyema of the pleura and bronchial fistulas are presented. The complex treatment included courses of hyperbaric oxygenation. The treatment procedure is described. Closure of the bronchial fistula and decrease in the fistula diameter were observed in 23 (33.8 per cent) and 16 (24.5 per cent) patients, respectively. No closure of the bronchial fistula in 41.7 per cent of the patients was recorded. Increased erythropoiesis, decreased leukocytosis and higher leukocyte counts, retarded ESR, lower contents of transaminases, increased inhibition of leukocyte migration, lower levels of immunoglobulin E and fewer numbers of immune complexes circulating in blood were revealed.

Adolescent↗