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Biomedical subjects

E P Melekhov

Publications and source records attributed to E P Melekhov.

12 recordsLinked to original sources

[Comparative characteristics of bactericidal activity of various traditional and currently available antiseptics used in surgery].

Comparative study of the microbicidal activity of some traditional (hydrogen peroxide, boric acid, nitrofurazone) and currently available (Baliz-2, dioxidine, chlorhexidine bigluconate, pervomur) antiseptics against the most commonly encountered causative agents of purulent surgical infection showed 0.8%, 1.2%, and 2.4% pervomur solutions to possess the highest bactericidal and sporicidal activity. This circumstance allowed weak (0.8 and 1.2%) solutions of pervomur to be used in the clinic in 68 patients for the management of purulent postoperative complications and localized purulent infection, which improved the results of treatment significantly.

Anti-Infective Agents, Local↗

[Use of pervomur in surgery].

The authors show the results of 15-year use of Pervomur solutions for sterilization of surgical material and treatment of the hands of surgeons in medical institutions of the country. Due to the high bactericidal properties of the agent its disinfectant effect is produced within a short time, which is of particular importance in mass admission of casualties in field conditions, in remote and mountainous wilderness, during natural disasters , and in performing surgical interventions on ships under conditions of prolonged autonomous cruises. The absence of an unfavourable effect of solutions of the agent on live tissue allows it to be considered a very promising antiseptic not only for sterilization but also for topical treatment of purulent wounds and cavities, particularly in contamination by polyinfection.

Anti-Infective Agents, Local↗

[Large-intestinal lesions in destructive pancreatitis].

An acute destructive pancreatitis may be followed by a lesion of the colon with its developing necrosis, narrowing etc. Seven cases with such complications are described. Problems of surgical tactics in patients with a destructive pancreatitis complicated by lesions of the colon are discussed.

Acute Disease↗

[Time periods of suture incompetence in anastomoses of the intra-abdominal organs].

The terms of incompetence of sutures of the sutured wound of the caval organs (anastomosis) were subjected to a careful retrospective analysis. In all the patients the diagnosis of failure of the sutures was confirmed in relaparotomy or in autopsy. It was established that the first signs of incompetence of sutures of intestinal anastomoses or a wound of the caval organs made their appearance within the first two days almost in two thirds of cases (118 patients) while within 3 postoperative days they developed in almost 90% of cases. The data obtained may be used for early diagnosis of incompetence of sutures of anastomoses of caval organs of the abdominal cavity.

Digestive System Surgical Procedures↗

[Computed tomography in the differential diagnosis of biliary, duodenal and pancreatic diseases].

The paper is concerned with analysis of CT-investigation of 150 patients with diseases of the bilio-pancreatoduodenal area, whose diagnosis was verified histologically or by clinical observation over time, using other methods (USI, RCPG, etc.). The authors have arrived at a conclusion that for increasing the informative value of CT one should use various methods of a contrast study of the duodenum and biliary tract, electron reconstruction of CT images in different projections. They have pointed out the most significant differential-diagnostic CT signs, proposed a table to facilitate the identification of causes and a level of obturation of the bile ducts, the table playing an important role in a choice of adequate therapy.

Bile Duct Diseases↗

[Computerized tomography in the differential diagnosis of biliopancreatoduodenal diseases].

The paper is concerned with analysis of CT-investigation of 150 patients with diseases of the biliopancreatoduodenal area, whose diagnosis was verified histologically or by clinical observation over time, using other methods, (USI, RCPG, etc.). The authors have arrived at a conclusion that for increasing the informative value of CT one should use various methods of a contrast study of the duodenum and biliary tract, electron reconstruction of CT images in different projections. They have pointed out the most significant differential-diagnostic CT signs, proposed a table to facilitate the identification of causes and a level of obturation of the bile ducts, the table playing an important role in a choice of adequate therapy.

Bile Duct Diseases↗