Biomedical subjects
Publications and source records attributed to E P Maksimov.
The paper describes the test specimen of an apparatus for performing hemodialysis and ultrafiltration using biologically active dialysates. The designed test specimen may serve as a technical base for further investigations and optimization of hemodialysis using a biologically active dialysate.
The paper deals with the optimization of a hemodialyzing procedure. An algorithm is proposed to set and control the profile of ultrafiltration in each specific moment of the hemodialyzing procedure, i.e. to control the basic parameters of the procedure as a hemodialysis time function.
Radical improvements in the physiological features and self-sufficiency of hemodialysis equipment, an essential reduction of the volume of dialyzate contacting with patient's body and elimination of dependence of the equipment operation on the availability of a water-supply network can be ensured by applying a regime of circulation of a relatively small volume (3-5 l) of dialyzate through the regenerating device. The regeneration unit must eliminate the organic products of dialysis from the dialyzate and stabilize the ionic composition of the purified dialyzate according to the preset parameters. Modern methods and technical means for regenerating the used dialyzate are discussed; a regeneration unit, which ensures an electrochemical oxidation (in the used dialyzate) of nitrogen-containing organic metabolites with a subsequent sorption-type additional purification of electrochemically-processed dialyzate, is offered. The regeneration unit is made up of an electrolyser, a sorption-type additional-purification device and a gas utilizer; it eliminates organic metabolites, phosphorus, calcium and potassium from the used dialyzate and stabilizes the pH solution.
The results of a study of parameters of an experimental dialyzate regeneration unit (a key functional unit of a hemodialysis apparatus with the regeneration of dialyzing solution) are discussed in the article.