Biomedical subjects
Publications and source records attributed to E P Ippen.
A mode-evolution-based polarization splitter suitable for high-index-contrast systems and directly integratable with a recently reported on-polarization rotator is described and its performance verified through both finite-difference time-domain and eigenmode expansion simulations. For a device length of 200 microm, greater than 22 dB of extinction is obtained across a 1.45-1.75-microm bandwidth.
Three-dimensional photonic waveguide devices are fabricated in glass by use of femtosecond pulses from an extended-cavity laser oscillator. Three-dimensional devices, including a symmetric three-waveguide directional coupler and a three-dimensional microring resonator, are fabricated and tested. Waveguides can be fabricated at depths of approximately 1 mm inside a glass substrate, thus demonstrating the capability of achieving dramatic increases in device density. These results demonstrate the potential to fabricate new classes of devices that are not possible in two dimensions.
Suppression of Q-switching instabilities with an actively controlled intracavity loss modulator is demonstrated in an Er-doped waveguide laser that is mode locked with a slow saturable absorber at repetition rates of as much as 100 MHz. By automatic gain control in the feedback loop, stable mode locking is achieved over the entire parameter range of the laser. This approach renders laser stabilization independent of the characteristics of the gain medium and intracavity power. The pulse-shaping dynamics is not affected by the presence of the intracavity loss modulator.
We demonstrate femtosecond performance of an ultrabroadband high-index-contrast saturable Bragg reflector consisting of a silicon/silicon dioxide/germanium structure that is fully compatible with CMOS processing. This device offers a reflectivity bandwidth of over 700 nm and subpicosecond recovery time of the saturable loss. It is used to achieve mode locking of an Er-Yb:glass laser centered at 1540 nm, generating 220-fs pulses, with what is to our knowledge the broadest output spectrum to date.
Real-time, ultrahigh-resolution optical coherence tomography (OCT) is demonstrated in the 1.4-1.7-microm wavelength region with a stretched-pulse, passively mode-locked, Er-doped fiber laser and highly nonlinear fiber. The fiber laser generates 100-mW, linearly chirped pulses at a 51-MHz repetition rate. The pulses are compressed and then coupled into a normally dispersive highly nonlinear fiber to generate a low-noise supercontinuum with a 180-nm FWHM bandwidth and 38 mW of output power. This light source is stable, compact, and broadband, permitting high-speed, real-time, high-resolution OCT imaging. In vivo high-speed OCT imaging of human skin with approximately 5.5-microm resolution and 99-dB sensitivity is demonstrated.
We demonstrate optical clockwork without the need for carrier-envelope phase control by use of sum-frequency generation between a continuous-wave optical parametric oscillator at 3.39 microm and a femtosecond mode-locked Ti:sapphire laser with two strong spectral peaks at 834 and 670 nm, a spectral difference matched by the 3.39-microm radiation.
Broadband saturable Bragg reflectors (SBRs) are designed and fabricated by monolithic integration of semiconductor saturable absorbers with broadband Bragg mirrors. The wet oxidation of AlAs creates low-index AlxOy layers for broadband, high-index-contrast AlGaAs/AlxOy or InGaAlP/AlxOy mirrors. SBR mirror designs indicate greater than 99% reflectivity over bandwidths of 294, 466, and 563 nm for center wavelengths of 800, 1300, and 1550 nm, respectively. Highly strained and unstrained absorbers are stably integrated with the oxidized mirrors. Large-scale lateral oxidation techniques permit the fabrication of SBRs with diameters of 500 microm. Large-area, broadband SBRs are used to self-start and mode lock a variety of laser systems at wavelengths from 800 to 1550 nm.
We describe a self-referenced optical frequency comb generator based on an octave-spanning, prismless Ti:sapphire laser. Dispersion compensation is provided by novel double-chirped mirror pairs and BaF2 wedges. Current versions operate at 80 and 150 MHz. The compact prismless design allows system scaling to a gigahertz repetition rate. Its carrier-envelope beat note is intrinsically stable with a signal-to-noise ratio of 30 dB in a 100-kHz bandwidth. The octave is reached at 25 dB below the average power level. The in-loop accumulated phase error is 1.4 rad (20 mHz to 1 MHz). The technique has the advantages of simplicity and stability compared with previous designs.
A balanced cross correlator, the optical equivalent of a balanced microwave phase detector, is demonstrated. Its use in synchronizing an octave-spanning Ti:sapphire laser and a 30-fs Cr:forsterite laser yields 300-attosecond timing jitter measured from 10 mHz to 2.3 MHz. The spectral overlap between the two lasers is strong enough to permit direct detection of the difference in carrier-envelope offset frequency between the two lasers.
Nonlinear optical effects due to the phase between carrier and envelope are observed with 5 fs pulses from a Kerr-lens mode-locked Ti:sapphire laser. These sub-two-cycle pulses with octave spanning spectra are the shortest pulses ever generated directly from a laser oscillator. Detection of the carrier-envelope phase slip is made possible by simply focusing the short pulses directly from the oscillator into a BBO crystal. As a further example of nonlinear optics with such short pulses, the interference between second- and third-harmonic components is also demonstrated.
The use of high intensity ultrashort pulsed laser radiation to produce optical breakdown is an important approach for the surgical treatment of intraocular structures. We have investigated the transient properties of Nd:YAG laser induced breakdown in a saline model using time-resolved spectroscopic techniques. Spatially resolved pump and probe techniques are applied to study the dynamic behavior of the plasma formation, acoustic wave generation, and cavitation processes which accompany the optical breakdown. Measurements of plasma shielding and luminescence indicate that the laser induced plasma forms on a subnanosecond time scale and has a lifetime of several nanoseconds. An acoustic transient is generated at the breakdown site and propagates spherically outward with an initial hypersonic velocity, then loses energy and propagates at sound velocity. Transient heating following the plasma formation produces a liquid-gas phase change and gives rise to cavitation or gas bubble formation. This gas bubble expands rapidly for several microseconds, then slows to reach its maximum size and finally collapses.
Subpicosecond pulses have been used to study the ultrafast dynamics of the photochemistry of bacteriorhodopsin. An optically induced absorption that appears in about 1.0 picosecond at physiological temperatures has been resolved in time. The data can be interpreted in terms of the photochemical formation of bathobacteriorhodopsin and provide support for an excitation mechanisms involving molecular rearrangement in the protein induced by electron redistribution in the chromophore.
Subpicosecond optical pulses have been used to study the photolysis of hemoglobin conplexes. Photodissociation of carboxyhemoglobin is found to occur in less than 0.5 picosecond. In hemoglobin and oxyhemoglobin a nondissociative excited state recovery in 2.5 picoseconds is observed.