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Biomedical subjects

E P Gotovtseva

Publications and source records attributed to E P Gotovtseva.

10 recordsLinked to original sources
PubMed1990

[Blood levels of opioid peptides and alpha interferon under the action of dipyridamole].

The levels of met-enkephalin (ME), beta-endorphin (BE), and alpha-interferon (a-IFN) have been determined in the human blood 1 day after dipyridamole administration. Dipyridamole led to an increase in serum a-IFN concentration up to 3 times, and to simultaneous rise of the lymphocytes ability to produce a-IFN. The content of BE did not depend on dipyridamole treatment, but ME level achieved 110 +/- 4.8 pg/ml (compare to 79.5 +/- 7.6 pg/ml in control). Positive interrelation has been found out between individual ME concentrations and lymphocyte abilities to a-IFN production with the coefficient of correlation equal to 0.69. The effect of dipyridamole on ME level is suggested to develop via a-IFN interaction with the opioid systems.

Adult↗
PubMedDate not supplied

[Use of recombinant alpha 2-interferon in athletes].

It has first been established that interferon preparations, especially reaferon, exert a protective antiviral effect in nonepidemic situations under conditions of physical and emotional stress leading to activation of opportunistic flora. Alongside with antiviral effect, reaferon showed a significant immunomodulating effect on the host reflected in blast transformation of T-lymphocytes and production of gamma-interferon. The immunoregulating action of reaferon was prolonged. These data suggest that exogenous use of reaferon may be one of the methods enhancing the resistance to emotional and physical stress.

Adolescent↗
PubMedDate not supplied

[Effects of MIGI-K on general resistance of the body].

The data on the effect of MIGI-K preparation, acidic hydrolyzate from mussel meat, on organism resistance are presented. The effect is based on the ability of MIGI-K to influence the level of endogenous compounds responsible for radioresistance, such as biogenic amines and lipid hydroperoxides, as well as certain parameters determining immune status of organism.

Adjuvants, Immunologic↗