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Biomedical subjects

E P Clerkin

Publications and source records attributed to E P Clerkin.

9 recordsLinked to original sources

Multiple distinct intracranial tumors: association of pinealoma and craniopharyngioma. Case report.

We report the case of a patient with multiple primary brain neoplasms. A pinealoma was treated with radiotherapy and surgical resection in 1983. In 1987, a craniopharyngioma was resected surgically. Various possible determinants of multiple brain tumors have been described in the literature and are discussed. The possibility of an unknown underlying pathologic mechanism predisposing to multiple malignancies must be considered, but we are unable to conclude that this particular occurrence is more than a random chance finding.

Adult↗

Hyperparathyroidism.

A review of hyperparathyroidism and current controversies in diagnosis and management is presented. Accurate diagnosis by the endocrinologist and an experienced surgeon remain the standards for good surgical results. Hyperparathyroidism is a heterogeneous disease, and therapy must be individualized to each patient. Conservative surgical removal of parathyroid tissue is preferred in most patients.

Adenoma↗

Hypercalcemia and malignant disease.

Virtually any malignancy may lead to hypercalcemia, but carcinoma of the breast, myeloma, and carcinoma of the lung are especially frequent offenders. A more difficult diagnostic problem is posed by the "silent" tumor which secretes a substance causing hypercalcemia. Foremost in this category are bronchogenic carcimona and hypernephroma.

Adenocarcinoma↗