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Biomedical subjects

E P Chenchikova

Publications and source records attributed to E P Chenchikova.

At least 19 recordsLinked to original sources

[The immunological indices in chronic glomerulonephritis with a varying clinical course].

Examination of children with chronic glomerulonephritis by means of using immunological indicators of the first level enabled a direct correlation (r = 60) to be established between the relative count of venous blood lymphocytes (the mean values of several studies) and the disease gravity. A regression equation is depicted, making it possible to identify a group at risk for a possible grave course of disease among patients with chronic glomerulonephritis. The relative count of T lymphocytes is the least dynamic and informative indicator for disease forecasting.

Child↗

[Study of the enzymatic activity of the blood leukocytes in experimental nephrotoxic nephritis in rats].

The enzymatic activity of blood leukocytes was studied in rats with Masugi nephritis by means of the quantitative cytochemical method. Nephrotoxin injection during first hours and days did not produce specific changes in the enzymatic activity. Maximum changes were observed on the 8-th day when the elevation of the activity of dehydrogenase lymphocytes and neutrophils acid phosphatase was observed at the same time with most pronounced histological changes in the kidneys, the decrease of the complement titer and the presence of nephrotoxin and autoglobulin in the renal glomeruli. Later the histological changes became less pronounced, and the enzymatic activity decreased. In rats with proteinuria the activity of the neutrophil leukocytes acid phosphatase was higher than in animals without proteinuria.

Acid Phosphatase↗