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Biomedical subjects

E Omenaas

Publications and source records attributed to E Omenaas.

48 records · Page 3Linked to original sources

Total and specific serum IgE levels in adults: relationship to sex, age and environmental factors.

We studied total and specific serum IgE levels cross-sectionally, potential predictors of obstructive lung disease, in a stratified random sample of 18-73-year-old adults (n = 1512). The attendance rate was 84%. The total IgE level and prevalences of specific IgE antibodies against house dust mite and cat were higher for men than for women. Specific IgE levels decreased by increasing age, while total IgE decreased in women only. Smokers had a higher IgE level than non-smokers, while non-smokers had more often specific IgE antibodies against timothy and birch than smokers. Subjects with occupational dust or gas exposure had a higher total IgE level than unexposed. The general population prevalences were for specific IgE antibodies against timothy 4.5%, house dust mite 3.2%, birch 2.6%, cat dander 1.6% mould 0.2% and against any of these 7.6%. In a multivariate analysis age, occupational dust or gas exposure as well as the interaction terms between sex and age and between smoking and pack-years were independent predictors for total IgE levels. Male sex, young age, never having smoked and the season of the year were independent predictors for having one or more of the five specific IgE antibodies. Subjects with total serum IgE in the highest quintile (> or = 66 kU/l) had an adjusted odds ratio of 37 (95% confidence interval: 11-120) for having one or more of the specific IgE antibodies examined, compared with those in the lowest quintile (< 5 kU/l). Demographic and environmental factors were thus predictors of total and specific IgE levels in this adult community.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

Single breath transfer factor for carbon monoxide in an asymptomatic population of never smokers.

BACKGROUND: Data on reference values of transfer factor variables in general populations of asymptomatic never smokers are limited. The aim of this study was to examine the relation between test variables and age, height, haemoglobin concentration and carboxyhaemoglobin concentration. METHODS: Measurements of single breath transfer factor for carbon monoxide (TLCO) were obtained for a randomly selected sample of never smokers in north western Europe who were 18-73 years old and had no respiratory symptoms or disorders. Two recordings of TLCO with a ratio of inspiratory vital capacity to forced vital capacity of greater than 0.09 were obtained by standardised techniques for 304 subjects. RESULTS: The measurement errors expressed as a percentage of the common mean value of TLCO, volume adjusted TLCO (KCO), and alveolar volume (VA) were 4.5%, 4.2%, and 2.4% respectively. Multiple linear regressions showed sex specific effects of height and age on TLCO, and, in addition, of haemoglobin and carboxyhaemoglobin concentrations on KCO. VA was associated with height but not with age. The 5th and 95th centiles for TLCO and KCO in men and women were between 78% and 82% and between 120% and 127%, respectively, of predicted values when age and height were taken into account. CONCLUSION: Reference equations and normal values for transfer test variables in a large healthy population of never smokers are described in relation to age, height, and haemoglobin concentrations. To our knowledge, this is the first report of an association between carboxyhaemoglobin concentrations and KCO in a population of never smoking men and women.

Adolescent↗

[Cerebral air embolism after percutaneous lung puncture].

Cerebral air embolism is a rare but serious complication to percutaneous transthoracic fine needle aspiration of the lung. A case is described after puncture of a tumour in the right lung with a 0.6 mm needle. The patient developed paralysis of the upper and lower extremities on his left side, probably due to an air embolism in the right middle cerebral artery. He was fully restituted after early hyperbaric treatment with oxygen.

Aged↗

[A basic course in pulmonary diseases as part of specialist training in internal medicine].

According to the new plan for specialist training in internal medicine in Norway eight different basic courses are planned. The first course in pulmonary medicine was arranged in 1988 and was attended by doctors from all parts of Norway. A theoretical and practical programme was set up for five days, covering central parts of pulmonary medicine. The participants asked for more case presentations and plenum discussions. A systematic educational system in each department of medicine which trains candidates for internal medicine, may further increase the benefit obtained from these basic courses.

Curriculum↗

[Cessation of smoking. Advice on how to stop smoking presented in a newspaper].

A journalist and a physician presented a smoking cessation campaign in four weekend editions of a Norwegian newspaper. A questionnaire was administered to 1,437 persons by telephone, 34% of the readers of the newspaper had actually read one or several of the articles and had gained information and know-how on how to stop smoking. However, only 2% of the readers who smoked daily tried to change their smoking habits.

Health Education↗

[Smoking prevention. Courses on smoking prevention conducted at a regional hospital].

We present the results of four smoking cessation courses conducted during the period 1986 to 1988 and including 105 persons. 68 women and 37 men participated in weekly lessons, three prior to and two after a predetermined quit-smoking day. Physicians presented information and smoking cessation techniques, the latter based on cognitive behavioural modification. At one year follow-up 27% of the participants had stopped smoking and 49% had reduced smoking consumption. More intensive follow-up and pharmacological treatment might reduce the relapse rate further.

Hospitals, District↗

Cerebral air embolism after transthoracic aspiration with a 0.6 mm (23 gauge) needle.

A 54 yr old man experienced weakness in his legs, ataxia and subsequent urinary retention after a percutaneous fine-needle aspiration of a tumor in the right lower lobe. Clinical neurological examination and electroencephalography revealed signs of a brain stem lesion, probably due to an air embolism to the basilar artery. The symptoms and signs gradually disappeared prior to, as well as after, hyperbaric oxygen treatment. We believe this to be the first case of air embolism after transthoracic puncture with a 23 gauge needle to be reported in medical literature.

Biopsy, Needle↗