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Biomedical subjects

E Olszewski

Publications and source records attributed to E Olszewski.

At least 91 records · Page 5Linked to original sources
PubMed1985

Cellular elements of the immune system in the larynx cancer, SEM study.

Observations that certain primary tumors (solid ones) are infiltrated by cells which participate in immune responses tend us to examine this problem in spontaneously growing larynx carcinoma (ca. planoepitheliale). Our observations in SEM revealed within but also in surrounding of cancer infiltrations the presence of cellular elements belonging to the immune system like: lymphocytes, monocytes and macrophages. The most numerous of them, lymphocytes, are brought to the surrounding and tumor's territory by very rich vascular network (angiogenesis phenomenon). Bidirectional transmigration of the lymphocytes, observed mainly within the postcapillary venules, takes place through the cytoplasm of endothelial cells. It is most probably that they are lymphocytes of T-type which are involved in a cell mediated mechanisms of the immune response against a tumor. The lymphocytes are responsible also for the presence of monocytes and especially macrophages within a tumor's territory. These facts suggest that the human organism, in certain degree, is able to fight against malignant tissue by similar mechanisms which are involved in the rejection of the graft.

Carcinoma↗
PubMed1981

Morphology of arteries, veins, and capillaries in cancer of the larynx: scanning electron-microscopical study on microcorrosion casts.

Morphology of blood vessels in cancer of the larynx, which as other solid tumors has great neoangiogenic abilities, was studied on microcorrosion casts in SEM. Most evident changes of the endothelial patterns were seen on the casts of capillaries, venules, and veins. Capillaries, especially the newly formed, are the most numerous constituent of the vascular bed in all zones of cancer of the larynx. These vessels exhibit great morphological differentiation varying from the single, blind-ended pipes via relatively long hairpin loops spirally twisted in the long axis, to strongly spiralled and convoluted loops, resembling pseudoglomeruli. The newly formed capillaries deriving predominantly from the host's capillaries, venules, and veins have a embryonal character. It seems reasonable to presume that the neoangiogenesis process triggered by active influence of the tumor angiogenesis factor, is in principle, a repetition of the mechanism of the embryonal angiogenesis.

Arteries↗
PubMed1980

Scanning electron microscopic studies on blood vessels in cancer of the larynx.

The injection replication method was used in a study of the vascular system in cancer of the larynx. Following maceration, clean microcorrosion casts of the blood vessels of larynx cancer were examined in a scanning electron microscope (SEM). The effective filling of the whole vasculature, including its finest capillaries, makes it possible to obtain really three-dimensional pictures of the tumor blood vessels in the SEM. These SEM pictures allow a more detailed and profound analysis of the behavior and arrangement of blood vessels in three basic, angioarchitectonically differentiated zones of the tumor.

Blood Vessels↗
PubMed1979

Bronchial asthma and pathological processes in the nasopharynx. I. Clinical analysis during remission and attack.

In 54 patients with bronchial asthma and a control group of 15 subjects laryngological, bacteriological and cytological examinations of the nasopharynx were performed. This region was found to be inflamed in 38% of the patients with asthma; in a group of asthmatic patients hypersensitive to aspirin, the percentage rose to 87%. In the asthmatic patients, as compared with the control group, there was a diminished neutrophilic exudate, a marked epithelial desquamation reaction and an abundant lymphocyticosinophilic exudate in a considerable percentage of cases.

Adult↗
PubMed1978

Sequential advancing flexion retention attachment: a locking device for the wrist-driven flexor hinge splint.

The Sequential Advancing Flexion Retention Attachment (SAFRA) was developed for cervical spinal cord-injured patients with a muscle grade of poor to fair in the wrist extensors. It is used on a standard wrist-driven flexor hinge hand splint with adjustable tenodesis bar. Through the development of the SAFRA, maintained prehension can be obtained without externally powered devices such as CO2 or electrically powered orthoses. The patient's increased functional abilities are discussed and advantages summarized.

Adult↗
PubMed1977

[Epidemiological study of chronic bronchitis in a population of workers in a fertilizer factory].

The authors investigated the influence of working conditions--with particular reference to dust and fluorite pollution--on the epidemiology of chronic bronchitis in 197 subjects working in a fertilizer producing plant in Krakow (Poland). The investigation included history, respiratory function tests (VC, TVC), height and weight measurement, rhinolaryngologic examination, nasal mucosa cytology and physical examination. The environmental survey included measurements of the dust respirable fraction and fluorite concentration in the air. The prevalence of chronic bronchitis was found to increase with the length of working activity and to be much higher in smokers than in non-smokers. Furthermore, in subjects working at the sites with the worst environmental situations it proved to be twice as high as in the remainders. Likewise higher proved to be the prevalence of laryngitis and sinusitis. The prevalence of chronic bronchitis was found to be much higher in workmen with more marked spirometric changes. In subjects affected with chronic bronchitis alterations of the nasal mucosa epithelium were also found.

Adult↗
PubMed1976

Blood vascular system in cancer of the larynx.

Injection methods were used for the study of the blood vascular system in 50 specimens from total or subtotal laryngectomy in patients with extensive cancer of the larynx, and in 24 normal postmortem larynges. All specimens were injected via the superior laryngeal arteries. A silicone rubber technique was found to be the most suitable for the aims of this study. A chaotic distribution of abnormal vessels that differ in shape, a rich neovascular network within the tumor, and capillary hypertrophy in its vicinity are the main features of the blood vascular system in laryngeal cancer. The results obtained indicate great tumor-angiogenic ability that can be indirectly explained by action of an angiogenesis factor diffusing from cancer cells. This may open new possibilities for the treatment of carcinoma of the larynx based on anti-angiogenesis.

Aged↗
PubMed1976

Vascularization of ossified cartilage and the spread of cancer in the larynx.

Twenty specimens for laryngectomy in extensive cancer of the larynx were examined after injecting the blood vessels with silicone rubber. The behavior of the vessels during the process of destruction of the laryngeal cartilages by the neoplasm were evaluated, as was the part played by the vascular system in spreading cancer in the larynx and its passage beyond the anatomical borders of this organ. Cartilages are damaged by cancer mainly in ossified and vascularized sites. The nonossified and avascular cartilages, on the contrary, are maintained in an almost unchanged condition amid the extensive tumorous masses surrounding them.

Aged↗