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Biomedical subjects

E O Levitskiĭ

Publications and source records attributed to E O Levitskiĭ.

11 recordsLinked to original sources
PubMed1983

[Cytological diagnosis of nodular hyperplasia and cancer of the prostate].

The results of histological and cytologic examination of the material obtained from 289 transrectal punction biopsies of the prostate carried out in 278 patients were compared. Smears were prepared from bioptates and stained haematoxylineosin after the method of Papenheim, Papanicolaou modified by A. V. Rudenko and L. K. Koonitsa. They were also treated with acridin orange (1:10,000). The histological examination established cancer in 66, nodose hyperplasia--97, chronic prostatitis--38, tuberculosis--4, fibrosis of prostatic stroma--9 and unaltered tissue in 48 cases. Cancer was suspected in 8 cases, while prostatic tissue was not identified in preparations in 8 cases. The cytological study detected cancer in 73 and chronic prostatitis in 42 cases. Cancer was suspected in 8 cases. No tumor or epithelial elements were identified in 148 and 7 cases, respectively. The cytological diagnosis was valid in 81% and cancer was erroneously diagnosed in 18 cases. Malignancy was not detected in 11 cancer patients. The cytological analysis failed to identify any difference between nodose hyperplasia and unaltered tissue of the prostate. It proved to be able to verify clear- and dark-celled adenocarcinoma as well as small cell and polymorphocellular carcinoma. However, it also failed to identify cribriform carcinoma and anaplastic adenocarcinoma.

Aged↗
PubMed1976

[Cytology and enzymocytochemistry of nodose hyperplasia and cancer of the prostate].

In cytological investigations the following forms of cancer of the prostate may be verified: differentiated (clear-cellular and dark-cellular adenocarcinoma); poorly differentiated; and nondifferentiated (microcellular and polymorphic-cellular cancer). In the unchanged epithelium of the prostate there was noted a high activity of acid phosphotase, nonspecific esterase, nonspecific 5'-exonuclease, acid RNA-ase, acid DNA-ase, leucine aminopeptidase, and the absence of activity of alkaline phosphotase, neutral DNA-ase, alkaline RNA-ase. In the cancerous epithelium the activity of leucine aminopeptidase was either drastically decreased or absent altogether; the activity of acid DNA-ase and acid RNA-ase was non-uniform with the tendency to decrease in poorly differentiated tumours. The activity of other investigated enzymes in the cancerous epithelium showed no significant changes. At early stages of development of squamous cell metaplasia in the epithelium there was identified alkaline RNA-ase dissapearing in manifested metaplastic changes.

Acid Phosphatase↗
PubMed1967

[Insuloma].

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Adenoma, Islet Cell↗