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Biomedical subjects

E Nava

Publications and source records attributed to E Nava.

40 records · Page 3Linked to original sources
PubMedDate not supplied

[Hepatic veno-occlusive disease associated with ingestion of Senecio tephrosioides].

A case of hepatic veno-occlusive disease (HVOD) in a 38 year-old woman is reported. She had occasionally consumed "Huamanrripa" (Senecio tephrosioides) as a cough remedy for many years. She was hospitalized because she had presented abdominal pain, jaundice and anasarca during 10 weeks. The histological studies of hepatic biopsy showed pronounced congestion to centrilobulillar predominance, focus of necrosis and a reversed lobulation pattern in some areas. In the next 13 months she was hospitalized four times due to complications of portal hypertension. This is the first reported case of HVOD associated with S tephrosioides ingestion. It is very probable that this plant used in peruvian traditional medicine contains pyrrolizidine alkaloids, hepatic and nephrotoxic substances that are present in other species of Senecio genus. Due to present popularity of alternative medicine, an increment in HVOD incidence is expected.

Adult↗
PubMedDate not supplied

[Radiology of nonpalpable breast lesions].

The authors reviewed 619 consecutive cases of breast nonpalpable lesions detected with mammography in which wire-directed open biopsy or stereotaxic biopsy was performed from 1984 to 1993. The ratio of benign to malignant biopsy findings was 4:1 for the whole series. The positive predictive value (PPV) of different radiologic pattern was determined. Biopsy is advised in the presence of patterns such as strongly suspect microcalcifications (granular or branching morphologic features), stellate masses, parenchimal distortion, opacities with undefined borders and asymmetric density, which yielded higher PPVs (26%, 93%, 92%, 35%, 42% and 19% respectively). However, follow-up with mammography is advised in probably benign lesions (opacity with regular borders and clusters of round or oval particles of calcifications), which yielded lower PPVs (1.5% and 3%). By decreasing the number of biopsies of probably benign lesions and thereby substantially reducing costs, this approach may help to widespread use of mammographic screening.

Adult↗