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E N Stenager

Publications and source records attributed to E N Stenager.

13 recordsLinked to original sources

Suicide and patients with neurologic diseases. Methodologic problems.

OBJECTIVE: The suicide risk in patients with many neurologic diseases has been reported to be greater than that in the general population. Studies on the subject are, however, often encumbered with methodologic problems. We appraised these problems and, based on an evaluation, reappraised knowledge of the suicide risk in patients with specific neurologic diseases. DATA SOURCE: Using the computerized database MEDLINE, we identified all published reports with the key words suicide, attempted suicide, and neurologic diseases. STUDY SELECTION: We assessed and reviewed studies concerning the most common neurologic diseases for methodologic problems in the study design. DATA EXTRACTION: The following methodologic problems emerged during our review: (1) choice of study type, ie, autopsy study or follow-up study; (2) choice of study population; (3) choice of control groups; (4) epidemiologic/statistical methods used; and (5) validity of statistics reported. DATA SYNTHESIS: We analyzed the methodologic problems in studies of patients with multiple sclerosis, epilepsy, Huntington's chorea, spinal cord lesions, cranial trauma, brain tumors, Parkinson's disease, vascular disorders, and migraine. In most of the studies, the methods used gave rise to uncertainty about the conclusion presented. CONCLUSION: An increased suicide risk was found in patients suffering from multiple sclerosis and spinal cord lesions as well as in selected groups of patients with epilepsy. In other neurologic diseases, the suicide risk may be increased, but the results are uncertain due to the methodologic problems in the study design.

Brain Injuries

Suicide and multiple sclerosis: an epidemiological investigation.

In a nationwide investigation the risk of death by suicide for patients with multiple sclerosis (MS) was assessed using records kept at the Danish Multiple Sclerosis Registry (DMSR) and the Danish National Register of Cause of Death. The investigation covers all MS patients registered with DSMR with an onset of the disease within the period 1953-85, or for whom MS was diagnosed in the same period. Fifty three of the 5525 cases in the onset cohort group committed suicide. Using the figures from the population death statistics by adjustment to number of subjects, duration of observation, sex, age, and calendar year at the start of observation, the expected number of suicides was calculated to be nearly 29. The cumulative lifetime risk of suicide from onset of MS, using an actuarial method of calculation, was 1.95%. The standard mortality ratio (SMR) of suicide in MS was 1.83. It was highest for males and for patients with onset of MS before the age of 30 years and those diagnosed before the age of 40. The SMR was highest within the first five years after diagnosis.

Adaptation, Psychological

MS mortality.

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Humans

[Attempted suicide and depression].

The frequency of depressive illness was investigated in 195 patients who had been referred consecutively after attempted suicide during the period 15. February 1989-15, October 1989. A total of 130 of these patients were admitted to hospital while the remainder were treated in the psychiatric emergency room or admission department. Registration of depressive symptoms on admission revealed that 85% had depressed mood and other depressive symptoms. According to the criteria established by Feighner et al. 51% suffered from definite depressive disease on admission. According to Zung's Depression Scale, 60% were depressed. On the basis of observations during hospitalization, 25% suffered from depressive disease according to the criteria established by Feighner et al. 19% of these patients suffered from endogenic depression according to the Newcastle I scale which corresponds to 5% of all the hospitalized patients with attempted suicide. Approximately 10% were treated with antidepressives. Only 8% were discharged with the diagnoses of endogenic or reactive psychoses (ICD-8). It is concluded that depressive symptoms occur in the majority of patients with attempted suicide but that slight non-endogenic depressive states are most commonly concerned and that many of these improve rapidly during hospitalization without medicinal treatment. Restraint should be observed in prescription of antidepressive medicine to patients with attempted suicide until the diagnosis of depressive disease is verified.

Adolescent

[Cancer and suicide. Review of the literature].

On the basis of the available literature about cancer and suicide, it is concluded that patients with cancer show a moderately increased risk of committing suicide. This risk is greatest during the first year after diagnosis of the disease. The forms of cancer which most frequently involves suicide are cancer in the gastro-intestinal canal in men and cancer of the breast and genitalia in women. Points of view as to how the risk of suicide in these patients may be reduced are presented and discussed.

Adult

[Prevention and after-care of suicidal behavior--a literature review].

In this review of the literature on studies concerning the prevention of suicide and the effect of after-care of patients who have attempted to take their lives it is concluded that no treatment which works has yet been discovered. Of five clinically controlled studies only one suggested that it affected the repetition frequency of attempts at suicide. When other effects were assessed there was an improvement in the patients' social functions and a reduction in their abuse of alcohol. The studies have shown that not only psychiatrists but also other physicians and categories of personnel can undertake attendance on, and after-care of patients who have attempted suicide provided that they receive the necessary training and supervision.

Aftercare

[Disseminated sclerosis: sexual and obstetrical aspects].

The onset of Multiple Sclerosis (MS) usually occurs at an early age and consequently often causes sexual problems. In the case of women, it also gives rise to doubts concerning whether or not it is justifiable to undertake pregnancy and childbirth under these circumstances. Such difficulties and doubts are described and guidelines submitted for appropriate forms of help, support and therapy which could be offered.

Adult

[Traditional and alternative treatment of patients with multiple sclerosis].

The medicine consumption and the employment of alternative treatment were investigated in a material of 117 patients with disseminated sclerosis (DS) considered to be a representative sample of the patients with DS in the County of Funen. This investigation revealed that the preparations most commonly employed to modify the disease among patients with disseminated sclerosis were: spasmolytics, agents to counteract neurogenic bladder symptoms, benzodiazepine and analgesics. The consumption of medicine increased with increasing handicap. Employment of psychopharmaca was commonest in patients in social classes 4 and 5 and in women. In addition, is was found that there was no difference in social class, sex and age among the patients who employ alternative methods of treatment. The patients themselves have not experienced any effect from alternative treatment.

Adult

[Pregnancy and disseminated sclerosis. A retrospective study].

A retrospective investigation was undertaken on 64 female patients with disseminated sclerosis (DS) on the Island of Funen. The object was to investigate whether pregnancy and delivery influenced the course of the disease. The results were standardized for the age of commencement and the duration of the disease. In addition, the available literature on the subject is reviewed. It was found that the group of women in whom the disease commenced before or in connection with pregnancy or delivery had more severe physical handicaps than women without children or in whom the disease commenced after the last delivery. Women in whom the disease commenced in connection with the last delivery were most severely handicapped. In women in whom the disease commenced more than six months after the last delivery, the long term prognosis is not poorer than for women without children.

Female