Search PubMed⌕ Search

Biomedical subjects

E N Starcke

Publications and source records attributed to E N Starcke.

11 recordsLinked to original sources
PubMed1978

Remineralization of enamel by a saliva substitute designed for use by irradiated patients.

A saliva substitute, VA-OraLube, was evaluated for ability to reharden dental enamel and to relieve intraoral soft tissue symptoms in patients receiving radiotherapy for malignancies of the head and neck. Treatments of 15, 30 and 60 minutes rehardened enamel by 3.1%, 4.0%, and 5.5%, respectively. In the second experiment, treatment for 60 minutes with the complete solution rehardened enamel by 5.2%. Omitting calcium, phosphorus and/or fluoride from the formulation greatly decreased this rehardening potential. Treatment of enamel with fresh whole saliva induced rehardening at a 7.3% level in comparison to the 5.5% and 5.2% derived by using the saliva substitute. Since the xerostomic patient usually uses the product very frequently, there is a remineralization potential of significant consequence. A total of 125 xerostomic patients used the saliva substitute on an ad lib basis over a period of 4 months. Patient responses indicated a very high level of acceptance and the virtual elimination of troublesome problems previously associated with the dry mouth state.

Head and Neck Neoplasms↗
PubMed1978

Alterations in whole saliva flow rate induced by fractionated radiotherapy.

Sequential changes in flow rate of whole saliva are detailed in 13 patients. Samples were collected without exogneous stimulation during a course of fractionated radiotherapy involving major portions of the salivary glands. Flow rate decreased markedly during the initial 3 treatment days and gradually thereafter until a minimal flow rate was reached. Early in the treatment, variable degrees of recovery were seen on Mondays following a weekend (Friday-Sunday) without treatment. After a minimal flow rate was reached, no such recovery was observed. Radiation needed to produce minimal flow varied from 450 to 4,050 rad. Patients with higher initial flow rates required higher dosages to reach the minimum. No return of secretory function was noted after extended periods of time.

Aged↗
PubMed1977

How critical is the interval between extractions and irradiation in patients with head and neck malignancy?

A total of sixty-two patients with head and neck malignancy who had teeth extracted prior to irradiation therapy were studied. Only one in this group of sixty-two patients developed posttherapy necrosis, and this instance was in no way related to the pre-irradiation extractions. Our experience with patients who have undergone extractions prior to radiotherapy indicates that exodontia may not be, within itself, associated with increased serious postirradiation sequelae. The incidence of osteoradionecrosis in these patients is extremely low. Further, our data do not indicate a critical time period for healing of extraction sockets prior to initiation of radiotherapy. When the state of the underlying disease allows, a healing time of 10 to 14 days should be granted when teeth are extracted prior to irradiation. This recommended interval is only a guideline, since a shorter healing time does not entail a significantly greater risk and should therefore not be arbitrarily classified as inappropriate.

Adult↗
PubMed1977

A saliva substitute for use by xerostomic patients undergoing radiotherapy to the head and neck.

A saliva substitute has been developed for use in veteran patients, primarity those undergoing radiotherapy for malignancy of the head and neck. The viscosity of the solution is adjusted to simulate that of whole saliva, and the electrolyte levels are similarly set. Fluoride is included at the level of 5.0 p.p.m. in an effort to enhance the mineralizing capacity of this preparation which is high in calcium and phosphate.

Chlorides↗
PubMed1975

Chemical protection against postirradiation dental caries.

Experience with dental caries in twenty-four patients receiving irradiation for malignant lesions of the head and neck demonstrates the critical importance of cooperation by the patient, a program of strict oral hygiene, and daily self-treatment with 0.4 per cent stannous fluoride gel. The ravaging form of dental caries associated with the postirradiation period can be essentially eliminated in cooperating patients. In nine patients who were uncooperative, fifty-seven crowns were amputated and an additional seventy-five carious surfaces were found 3.75 years after irradiation. In six patients who cooperated and used the gel on a daily basis, no crowns were amputated and only one carious area was found over the same time period.

Dental Caries↗
PubMed1975

A historical review of complete denture impression materials.

The history of complete denture impression procefures has been influenced largely by the development of impression materials from which new ideas and techniques arose. Apparently, some procedures have been devised solely for the promotion of certain impression materials. For the most part, however, impression materials have been developed to accomplish specific goals and, at the time at least, were considered desirable for the purpose.

Acrylic Resins↗