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E Montserrat

Publications and source records attributed to E Montserrat.

366 records · Page 21Linked to original sources
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[Multilocular cystic nephroma. A diagnostic problem].

A multilocular cystic nephroma is described in a female patient diagnosed as having a mucinous cystadenocarcinoma of the left ovary, treated by surgery. It is presented as a mixed mass in the left kidney; image findings were specified with the new image diagnostic methods currently available, ultrasonography and computerized tomography. In the ultrasonographic study the mass is presented as an heterogenous image, with multiple anecogenic areas, separated by more ecogenic bands, situated mainly in the lower pole affecting all the cortical area and occasionally invading renal sinus. In the computerized tomography study a cystic mass is observed, with cysts of a different size that, after administering intravenous iodine, show a density increase in intercystical fibrous tracts. In cases with more complex image presentations, fine needle puncture is recommended, preferably in different areas in the mass in order to rule out the presence of malignant cells.

Aged↗
PubMedDate not supplied

Estimation of bone marrow cellularity by means of vertebral magnetic resonance.

BACKGROUND AND OBJECTIVE: A magnetic resonance (MR) signal shows an inverse correlation with bone marrow cellularity. In this study, we investigated the possibility of estimating the degree of bone marrow cellularity by means of this non-invasive technique. METHODS: In 25 patients with different hematological disorders and homogeneous bone marrow distribution, the percentage of bone marrow cellularity was compared to the MR signal of four middorsal vertebrae in T1 sequence. As internal control, the MR signal of the mid-dorsal spinal cord region was used. The results were expressed as the MR signal ratio (great mean MR signal of four vertebrae/MR signal of the spinal cord). RESULTS: The correlation coefficient (r) between both parameters was -0.93 (p < 0.0001). All observed values fell within the 90% limits of predicted values. The mean difference between observed and predicted bone marrow cellularity was 5.6 (SD 4.0)%. INTERPRETATION AND CONCLUSIONS: The measurement of the MR signal is not easy to standardize since it depends to a large degree on the control employed. The spinal cord proved to be a satisfactory internal control of the MR signal. Within defined conditions, MR can be useful for a rough estimate of bone marrow cellularity in several clinical situations, such as analysis of tumor burden for prognosis of some leukemias and the evaluation of response to therapy in both proliferative and hypoplastic disorders.

Adolescent↗
PubMedDate not supplied

Simultaneous occurrence of B-cell chronic lymphocytic leukemia and chronic myeloid leukemia with further evolution to lymphoid blast crisis.

The coexistence of chronic myeloid leukemia (CML) and B-cell chronic lymphocytic leukemia (CLL) in the same patient is rare. A 71-year-old woman developed a B-lineage lymphoid blast crisis at 18 months after diagnosis of Ph-positive CML. At this time, a lymphoid cell population with morphologic and immunophenotypic features of CLL was demonstrated. The retrospective review of the tests performed at diagnosis and thereafter disclosed the presence of lymphoid nodules in the initial bone marrow biopsy in the absence of lymphocytosis. Subsequently, there was an appearance of moderate lymphocytosis in the following months. Therefore, diagnosis of CML and coexistent CLL was established. Although a transient remission of blast crisis was achieved, blast cells reappeared two months later and the patient died shortly afterwards. Molecular studies of the immunoglobulin heavy chain gene (IH) rearrangement pattern point to the origin of the diseases in two different cell clones. In addition, previously published cases of simultaneous CLL and CML are reviewed.

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