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Biomedical subjects

E Mayer

Publications and source records attributed to E Mayer.

At least 217 records · Page 12Linked to original sources
PubMed1977

Use of 1alpha-hydroxycholecalciferol in the prevention of bovine parturient paresis.

A synthetic biologically active derivative of vitamin D (350 microgram of 1alpha-hydroxycholecalciferol [1alpha(OH)CC]) was injected into 2 nonlactating 7-year-old Israeli-Friesian cows. Plasma calcium values increased after 24 hours, peaked at 48 hours, and returned to base-line values 120 hours after injection. An injection of 350 microgram of 1alpha(OH)CC was given to 23 parturient-paresis-prone Israeli-Friesian cows from 7 days to 6 hours prepartum; 13 cows were injected once, 6 were injected twice, and 4 were injected 3 times, all at 48-hour intervals. Parturient-paresis-prone cows (n = 23) of the same breed were used as controls. Within 0 to 36 hours postpartum, plasma calcium concentrations were found to be higher in cows injected with 1alpha(OH)CC than in the control cows. The increase was highly significant (P less than 0.01) in cows injected at least twice. None of the cows injected with 1alpha(OH)CC, within 72 to 24 hours prior to calving developed parturient paresis; but 9 of 23 control cows developed parturient paresis. Prior to calving, none of the injected cows developed hypercalcemia and there was no local or systemic clinically detectable signs of toxiosis. When given at the right time prepartum, 1alpha(OH)CC is considered to be an improvement over previous methods of preventing bovine parturient paresis.

Animals↗
PubMed1975

Immunological studies of the anticryptococcal factor of normal human serum.

Preliminary studies have shown a very high inhibitory activity in the alpha2 and gamma zone of human serum towards the growth of Cryptococcus neoformans. These findings are now corroborated by single radial immunodiffusion tests, which showed the some loss of IgA and IgM globulins and of the other three globulin fractions (ceruloplasmin, alpha2 macroglobulin and alpha2 HS glycoprotein) which migrate in the alpha2 zone. The data was obtained by single radial immunodiffusion tests. The losses were not statistically significant however. No change in the immunoglobulin content of the sera kept for 6 days in contact with a heat-killed suspension of C. neoformans was noted. These findings suggest, that the inhibitory activity of the normal human serum on the in-vitro growth of C. neoformans is due to the above mentioned globulin fractions and not to a single specific factor.

Antibodies, Fungal↗
PubMed1975

[The effect of long term antibacterial treatment following prostatic surgery. A comparative study in 96 patients].

In a prospective, randomized study in 96 patients undergoing prostatic surgery (92 patients) and extensive transurethral bladder surgery (4 patients) all patients received postoperative antibiotics for five days. Following this the patients were divided into two groups. Group A received Bactrim for three months and Group B received a placebo for three months. Urine cultures were carried out six times during this three month period. In Group A, 13 patients (25%) were infected preoperatively and 9 patients (17%) postoperatively. In group B, 10 patients (22.8%) were infected preoperatively and 9 patients (20.5%) postoperatively. There was no significant difference between the results in the two groups. These and other results allow the following conclusions: 1. Routine postoperative long term treatment with antibacterial substances has no significant effect on the postoperative urinary tract infection. 2. Long term preoperative indwelling catheter treatment increases the incident of postoperative urinary tract infection. This can be prevented by operating patients early following the first urinary retention. It is confirmed that there is an increased risk of persistent urinary tract infection in patients with neurogenic bladder disturbances, preoperative ureteral dilatation, diabetes mellitus and various other complications.

Catheters, Indwelling↗