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E May

Publications and source records attributed to E May.

147 records · Page 9Linked to original sources

Treatment of the SpA-like disease in HLA B27 transgenic animals.

A major involvement of the immune system and of microbial flora in the HLA-B27 transgenic rat model of spondylarthropathy was demonstrated. The role of inflammatory pathways, such as cytokines and inducible nitric oxide synthase (iNOS) was investigated. Treatment with IL-10 failed to improve established disease, whereas such improvement was achieved with IL-11. In contrast, aggravation was observed after treatment with selective inhibitor of iNOS.

Animals↗